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A team led by UT Southwestern Medical Center researchers has identified a key mechanism responsible for endosomal recycling in cells, a process critical to human health. Their findings, published in Nature Communications, answer a fundamental question in cell biology and could lead to therapies for conditions including neurological disorders and cancer.

A team led by UT Southwestern scientists has discovered a mechanism that promotes metastasis in pancreatic, breast, and potentially other cancers along with a new druggable therapeutic target based on this mechanism to block metastases.

A far shorter, simpler, and less toxic treatment protocol for patients with triple-negative breast cancer produced outcomes similar to the current standard of care, a clinical trial co-led by a UT Southwestern Medical Center researcher shows.

UT Southwestern Medical Center is part of a major undertaking that will bring together more than 40 scientists, doctors, and industry experts handpicked from around the country to make vision-restoring whole eye transplants a reality.

As a young man in his mid-20s, Jorge Gómez was one of thousands of Cuban citizens who fled communism and the island country on a raft in 1994. He would spend 11 months living in a tent city at Guantanamo Bay before being granted asylum in the U.S., where he overcame numerous obstacles to build a better life as an engineer and father of four boys in Carrollton, Texas.

Mutations in a gene called OTP cause obesity by controlling the output of another gene already targeted by an anti-obesity drug, a study led by UT Southwestern Medical Center researchers shows.

UT Southwestern Medical Center researchers have identified how the quintessential immune protein known as stimulator of interferon genes (STING) migrates from one cellular organelle to another, a necessary step in its activation.

UT Southwestern Medical Center and InterAct Therapeutics have announced an exclusive licensing agreement to develop and commercialize a groundbreaking computational platform and gene therapy pipeline targeting cancer metastasis.

A study led by a researcher at UT Southwestern Medical Center shows a national initiative significantly improved stroke outcomes for millions of patients over its first 20 years, enhancing quality of care and consistency at more than 2,800 U.S. hospitals including UTSW.

Jiang He, M.D., Ph.D., Professor and Chair Designate of Epidemiology in the Peter O’Donnell Jr. School of Public Health at UT Southwestern Medical Center, is a 2024 recipient of the American Heart Association’s (AHA) highest commendation, the Distinguished Scientist award.