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The National Cancer Institute has renewed the Harold C. Simmons Comprehensive Cancer Center’s comprehensive designation, reaffirming its place among the country’s elite cancer institutes.

People who had a potentially allergic reaction to their first messenger RNA COVID-19 vaccination can safely receive their second shot, according to a study of patients conducted at several medical centers, including UT Southwestern.

UT Southwestern researchers report the first structural confirmation that endogenous – or self-made – molecules can set off innate immunity in mammals via a pair of immune cell proteins called the TLR4-MD-2 receptor complex.

Using a virus to purposely mutate genes that produce cancer-driving proteins could shed light on the resistance that inevitably develops to cancer drugs that target them, a new study led by UT Southwestern scientists suggests.

A healthy diet, regular exercise, and sufficient sleep can help prevent the onset of diabetes, a condition affecting more than 37 million Americans, according to Bethany Agusala, M.D., Assistant Professor of Internal Medicine at UT Southwestern.

UT Southwestern researchers have discovered a molecular pathway that allows cells to sense when their lipid supplies become depleted, prompting a flurry of activity that prevents starvation. The findings, reported in Nature, might someday lead to new ways to combat metabolic disorders and a variety of other health conditions.

A generous $25 million commitment from the Once Upon a Time Foundation will create the Raynor Cerebellum Project at UT Southwestern Medical Center (RCP-UTSW) to investigate diseases associated with cerebellum dysfunction, with the goal of discovering how to preserve and restore lost brain function.

Hip and knee replacements, sports injuries, trauma. That’s typically what comes to mind when one thinks of orthopedic surgery, not diabetes.

Scar-like cells that make up a sizable portion of malignant pancreatic tumors and shield these cancers from immune attack are derived from mesothelial cells that line tissues and organs, a new study led by UT Southwestern researchers suggests.

UT Southwestern researchers Zhijian “James” Chen, Ph.D., and Sihan Wu, Ph.D., are part of a team that has been awarded a Cancer Grand Challenges grant, a unique award that aims to solve some of cancer’s toughest problems by bringing together global teams with diverse areas of expertise.