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A Paper by Siqi Liu And Jueqi Chen Is Published on eLife | Chen Lab | UT Southwestern, Dallas, Texas

https://labs.utsouthwestern.edu/chen-zhijian-james-lab/paper-siqi-liu-and-jueqi-chen-published-elife

A Paper by Hui Xu is published in eLife

February 2014 | Chen Lab | UT Southwestern, Dallas, Texas

https://labs.utsouthwestern.edu/chen-zhijian-james-lab/february-2014

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A Paper by Siqi is published in Science | Chen Lab | UT Southwestern, Dallas, Texas

https://labs.utsouthwestern.edu/chen-zhijian-james-lab/paper-siqi-published-science

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Siqi Liu Defended Her Dissertation | Chen Lab | UT Southwestern, Dallas, Texas

https://labs.utsouthwestern.edu/chen-zhijian-james-lab/siqi-liu-defended-her-dissertation

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A Paper by Daxing Gao Is Published in Science | Chen Lab | UT Southwestern, Dallas, Texas

https://labs.utsouthwestern.edu/chen-zhijian-james-lab/paper-daxing-gao-published-science

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Two Papers by Lijun Sun and Jiaxi Wu Are Published In Science | Chen Lab | UT Southwestern, Dallas, Texas

https://labs.utsouthwestern.edu/chen-zhijian-james-lab/two-papers-lijun-sun-and-jiaxi-wu-are-published-science

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Publications | Reinecker Lab | UT Southwestern, Dallas, Texas

https://labs.utsouthwestern.edu/reinecker-lab/publications

Skip to main content Publications Featured Publications Bacterial Peptidoglycan Fragments Differentially Regulate Innate Immune Signaling. Bersch KL, DeMeester KE, Zagani R, Chen S, Wodzanowski KA, Liu S, Mashayekh S, Reinecker HC , Grimes CL, ACS Cent Sci 2021 Apr 7 4 688-696 GEF-H1 Signaling upon M…

Microbial Pattern Recognition | Reinecker Lab | UT Southwestern, Dallas, Texas

https://labs.utsouthwestern.edu/reinecker-lab/research/microbial-pattern-recognition

Skip to main content Microtubule-Based Microbial Pattern Recognition System Cells contain a reservoir of inactive GEF-H1 bound to microtubules that is activated by dephosphorylation to form signaling platforms for the activation of innate and cell-autonomous immunity. Muramyl-dipeptide (MDP) is the m…

Anti-Tumor Immunity | Reinecker Lab | UT Southwestern, Dallas, Texas

https://labs.utsouthwestern.edu/reinecker-lab/research/anti-tumor-immunity

Skip to main content GEF-H1-Dependent Regulation of Anti-Tumor Immunity We discovered that intracellular activation of the GEF-H1 signaling pathway induces immune responses and dendritic cell maturation similar to microbial pattern recognition receptors. GEF-H1 directed immunity emerges as a critical…

Research | Reinecker Lab | UT Southwestern, Dallas, Texas

https://labs.utsouthwestern.edu/reinecker-lab/research

Skip to main content Research A Microtubule-Based Microbial Pattern Recognition System Our work has revealed polymorphisms that show that microbial defense systems could be linked to human autoimmune diseases. Find out more Development of Mucosal Immunity We study human genetic diversity associated w…