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www.elsevier.com/locate/jconrel Journal of Controlled Release 98 (2004) 415–426 Micellar carriers based on block copolymers of poly(q-caprolactone) and poly(ethylene glycol) for doxorubicin delivery Xintao Shuaia,1, Hua Aia,1, Norased Nasongklab, Saejeong Kima, Jinming Gaoa,* aDepartment of Biom…

In vivo drug distribution dynamics in thermoablated and normal rabbit livers from biodegradable polymers Jinming Gao,1 Feng Qian,1 Agata Szymanski-Exner,1 Nicholas Stowe,2 John Haaga3 1Cancer-Targeted Drug Delivery Laboratory, Department of Biomedical Engineering, Case Western Reserve University, C…

Fabrication and characterization of controlled release poly(D,L-lactide-co-glycolide) millirods Feng Qian, Agata Szymanski, Jinming Gao Cancer-Targeted Drug Delivery Laboratory, Department of Biomedical Engineering, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio 44106 Receive…

628 graft morphology and function have not been adequately addressed. A systematic understanding of the effects of in vitro parameters will be important if these culture tech- niques are to be translated to human cells for the develop- ment of autologous human vascular grafts that have acceptable lo…

10 to 70% methanol in 50 mM KH2PO4 over 25 min, 10 ml/min, monitor at 380 nm). Next, the HPLC- purified mixture was desalted on the same column (methanol was removed on a rotary evaporator, and the sample loaded in H2O and eluted with 90% methanol) and lyophilized, yielding the purified Nvoc-aa-S-CoA…

Journal of Controlled Release 83 (2002) 427–435 www.elsevier.com/ locate/ jconrel C ombined modeling and experimental approach for the development of dual-release polymer millirods *Feng Qian, Gerald M. Saidel, Damon M. Sutton, Agata Exner, Jinming Gao Cancer-Targeted Drug Delivery Laboratory, Depa…

COMMUNICATIONS Surface Modification of Polyanhydride Microspheres JINMING GAO†,‡, LAURA NIKLASON†,‡, XIAO-MEI ZHAO§, AND ROBERT LANGER*,† Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, Department of Anesthesia, Massachusetts General Hospi…

Surface hydrolysis of poly(glycolic acid) meshes increases the seeding density of vascular smooth muscle cells Jinming Gao,1,2 Laura Niklason,1,2 Robert Langer1 1Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139 2Department of Anesthesia, Mass…

Probing the Energetics of Dissociation of Carbonic Anhydrase-Ligand Complexes in the Gas Phase Jinming Gao,* Qinyuan (Quincey) Wu,# Jeffrey Carbeck,* Q. Paula Lei,# Richard D. Smith,# and George M. Whitesides* *Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusett…

Correlation between the Charge of Proteins in Solution and in the Gas Phase Investigated by Protein Charge Ladders, Capillary Electrophoresis, and Electrospray Ionization Mass Spectrometry Jeffrey D. Carbeck,† Joanne C. Severs,‡ Jinming Gao,† Qinyuan Wu,‡ Richard D. Smith,* ,‡ and George M. Whitesid…