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B � p o A r c B O S 6 P Int. J. Radiation Oncology Biol. Phys., Vol. 61, No. 1, pp. 212–219, 2005 Copyright © 2005 Elsevier Inc. Printed in the USA. All rights reserved 0360-3016/05/$–see front matter doi:10.1016/j.ijrobp.2004.09.018 IOLOGY CONTRIBUTION SUSCEPTIBILITY OF CANCER CELLS TO �-LAPA…

www.elsevier.com/locate/jconrel Journal of Controlled Release 98 (2004) 415–426 Micellar carriers based on block copolymers of poly(q-caprolactone) and poly(ethylene glycol) for doxorubicin delivery Xintao Shuaia,1, Hua Aia,1, Norased Nasongklab, Saejeong Kima, Jinming Gaoa,* aDepartment of Biom…

Journal of Controlled Release 91 (2003) 157–166 www.elsevier.com/ locate/ jconrel Q uantification of in vivo doxorubicin transport from PLGA millirods in thermoablated rat livers a ,1 b a a a ,*Feng Qian , Nicholas Stowe , Erin H. Liu , Gerald M. Saidel , Jinming Gao aDepartment of Biomedical Engin…

Enhancement of Solubility and Bioavailability of �-Lapachone Using Cyclodextrin Inclusion Complexes Norased Nasongkla,1,2 Andy F. Wiedmann,2 Andrew Bruening,3 Meghan Beman,3 Dale Ray,4 William G. Bornmann,5 David A. Boothman,3 and Jinming Gao2,6 Received June 11, 2003; Accepted June 19, 2003 Pur…

In vivo drug distribution dynamics in thermoablated and normal rabbit livers from biodegradable polymers Jinming Gao,1 Feng Qian,1 Agata Szymanski-Exner,1 Nicholas Stowe,2 John Haaga3 1Cancer-Targeted Drug Delivery Laboratory, Department of Biomedical Engineering, Case Western Reserve University, C…

155 O R I G I N A L R E S E A R C H International Journal of Nanomedicine 2006:1(2) 155–162 © 2006 Dove Medical Press Limited. All rights reserved Abstract: Small interfering RNA molecules (siRNA) hold great promise to specifically target cytoprotective factors to enhance cancer therapy. Like a…

10 to 70% methanol in 50 mM KH2PO4 over 25 min, 10 ml/min, monitor at 380 nm). Next, the HPLC- purified mixture was desalted on the same column (methanol was removed on a rotary evaporator, and the sample loaded in H2O and eluted with 90% methanol) and lyophilized, yielding the purified Nvoc-aa-S-CoA…

Fabrication and characterization of controlled release poly(D,L-lactide-co-glycolide) millirods Feng Qian, Agata Szymanski, Jinming Gao Cancer-Targeted Drug Delivery Laboratory, Department of Biomedical Engineering, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio 44106 Receive…

COMMUNICATIONS Surface Modification of Polyanhydride Microspheres JINMING GAO†,‡, LAURA NIKLASON†,‡, XIAO-MEI ZHAO§, AND ROBERT LANGER*,† Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, Department of Anesthesia, Massachusetts General Hospi…

Surface hydrolysis of poly(glycolic acid) meshes increases the seeding density of vascular smooth muscle cells Jinming Gao,1,2 Laura Niklason,1,2 Robert Langer1 1Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139 2Department of Anesthesia, Mass…