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ARTICLE Small-molecule TFEB pathway agonists that ameliorate metabolic syndrome in mice and extend C. elegans lifespan Chensu Wang1,2, Hanspeter Niederstrasser3, Peter M. Douglas4, Rueyling Lin4, Juan Jaramillo4, Yang Li1, Nathaniel W. Olswald3, Anwu Zhou3, Elizabeth A. McMillan2, Saurabh Mendiratt…

NATURE BIOMEDICAL ENGINEERING 1, 0006 (2016) | DOI: 10.1038/s41551-016-0006 | www.nature.com/natbiomedeng 1 ARTICLES PUBLISHED: 19 DECEMBER 2016 | VOLUME: 1 | ARTICLE NUMBER: 0006 A transistor-like pH nanoprobe for tumour detection and image-guided surgery Tian Zhao1​†, Gang Huang1, Yang Li1, Shu…

Advanced Drug Delivery Reviews xxx (2016) xxx–xxx ADR-13057; No of Pages 10 Contents lists available at ScienceDirect Advanced Drug Delivery Reviews j ourna l homepage: www.e lsev ie r .com/ locate /addr Investigation of endosome and lysosome biology by ultra pH-sensitive nanoprobes☆ Chensu Wang …

Ultra-pH-Sensitive Nanoprobe Library with Broad pH Tunability and Fluorescence Emissions Xinpeng Ma,†,‡ Yiguang Wang,†,‡ Tian Zhao,† Yang Li,† Lee-Chun Su,† Zhaohui Wang,† Gang Huang,† Baran D. Sumer,§ and Jinming Gao*,†,∥ †Department of Pharmacology and §Department of Otolaryngology, Simmons Compr…

Micellization DOI: 10.1002/anie.201402525 Chaotropic-Anion-Induced Supramolecular Self-Assembly of Ionic Polymeric Micelles** Yang Li, Yiguang Wang, Gang Huang, Xinpeng Ma, Kejin Zhou, and Jinming Gao* Dedicated to Professor George M. Whitesides on the occasion of his 75th birthday Abstract: Tradi…

Contents lists available at ScienceDirect Journal of Controlled Release journal homepage: www.elsevier.com/locate/jconrel Synthetic nanovaccines for immunotherapy Min Luoa, Layla Z. Samandia, Zhaohui Wanga, Zhijian J. Chenb,c, Jinming Gaoa,⁎ a Department of Pharmacology, Simmons Comprehensive Ca…

Targeting the Oncogene KRAS Mutant Pancreatic Cancer by Synergistic Blocking of Lysosomal Acidification and Rapid Drug Release Chao Kong,† Yang Li,‡ Zhengsheng Liu,† Junxiao Ye,† Zhaohui Wang,‡ Ling Zhang,† Weijian Kong,† Huiqin Liu,† Chun Liu,† Huanhuan Pang,§ Zeping Hu,§ Jinming Gao,*,‡ and Feng Q…