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Research | Reinecker Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/reinecker-lab/research
Skip to main content Research A Microtubule-Based Microbial Pattern Recognition System Our work has revealed polymorphisms that show that microbial defense systems could be linked to human autoimmune diseases. Find out more Development of Mucosal Immunity We study human genetic diversity associated w…
Mucosal Immunity | Reinecker Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/reinecker-lab/research/mucosal-immunity
Skip to main content Development of Mucosal Immunity We study human genetic diversity associated with inflammatory bowel diseases to understand the principal mechanisms of mucosal immunity that control the intestinal barrier function and the microbiome. Immune responses control host defenses intestin…
Microbial Pattern Recognition | Reinecker Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/reinecker-lab/research/microbial-pattern-recognition
Skip to main content Microtubule-Based Microbial Pattern Recognition System Cells contain a reservoir of inactive GEF-H1 bound to microtubules that is activated by dephosphorylation to form signaling platforms for the activation of innate and cell-autonomous immunity. Muramyl-dipeptide (MDP) is the m…
A Paper by Daxing Gao Is Published in Science | Chen Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/chen-zhijian-james-lab/paper-daxing-gao-published-science
Read Daxing's paper
Two Papers by Lijun Sun and Jiaxi Wu Are Published In Science | Chen Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/chen-zhijian-james-lab/two-papers-lijun-sun-and-jiaxi-wu-are-published-science
Read both papers
Siqi Liu Defended Her Dissertation | Chen Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/chen-zhijian-james-lab/siqi-liu-defended-her-dissertation
See photos of the event
Join Us | Whitehurst Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/whitehurst-lab/join-us
Skip to main content Join Us Become a Team Member The Whitehurst lab is seeking energetic, dedicated graduate students and postdoctoral fellows to join our work. Current Projects Cancer-Testis Antigens (aka Cancer Germline Genes) Cancer-testis antigens are normally only expressed in testis, but we ha…
Anti-Tumor Immunity | Reinecker Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/reinecker-lab/research/anti-tumor-immunity
Skip to main content GEF-H1-Dependent Regulation of Anti-Tumor Immunity We discovered that intracellular activation of the GEF-H1 signaling pathway induces immune responses and dendritic cell maturation similar to microbial pattern recognition receptors. GEF-H1 directed immunity emerges as a critical…
A nanoparticle-based strategy for the imaging of a broad range of tumours by nonlinear amplification of microenvironment signals
https://labs.utsouthwestern.edu/sites/default/files/2022-11/102_Wang_Nat_MaterRed.pdf
ARTICLES PUBLISHED ONLINE: 8 DECEMBER 2013 | DOI: 10.1038/NMAT3819 A nanoparticle-based strategy for the imaging of a broad range of tumours by nonlinear amplification of microenvironment signals Yiguang Wang1, Kejin Zhou1, Gang Huang1, Christopher Hensley2, Xiaonan Huang1, Xinpeng Ma1, Tian Zhao1, …
acs_nn_nn-2011-03503h 1..10
https://labs.utsouthwestern.edu/sites/default/files/2022-11/91_Yu_ACSNano.pdf
YU ET AL . VOL. 5 ’ NO. 11 ’ 9246–9255 ’ 2011 www.acsnano.org 9246 October 19, 2011 C 2011 American Chemical Society Overcoming Endosomal Barrier by Amphotericin B-Loaded Dual pH-Responsive PDMA-b-PDPA Micelleplexes for siRNA Delivery Haijun Yu,† Yonglong Zou,†,‡ Yiguang Wang,† Xiaonan Huang,† G…