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Contact Us | Zhong Lab | UT Southwestern, Dallas, Texas

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Join Us | Zhong Lab | UT Southwestern, Dallas, Texas

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Research | Zhong Lab | UT Southwestern, Dallas, Texas

https://labs.utsouthwestern.edu/zhong-lab/research

Learn about Zhong Lab's research.

Publications | Zhong Lab | UT Southwestern, Dallas, Texas

https://labs.utsouthwestern.edu/zhong-lab/publications

Zhong Lab publications.

People | Yin Lab | UT Southwestern, Dallas, Texas

https://labs.utsouthwestern.edu/yin-lab/people

Get to know our Principal Investigator and team of researchers at Helen Yin Lab.

Gelsolin regulates the actin cytoskeleton and membrane signaling | Yin Lab | UT Southwestern, Dallas, Texas

https://labs.utsouthwestern.edu/yin-helen-lab/research/gelsolin-regulates-actin-cytoskeleton-and-membrane-signaling

We now want to know how gelsolin and gelsolin-like proteins behave in living cells. We are developing a fluorescence energy transfer reporter to monitor gelsolin activation in live cells.

Autophagosome: Lysosome fusion | Yin Lab | UT Southwestern, Dallas, Texas

https://labs.utsouthwestern.edu/yin-lab/yin-helen-lab/research/autophagosome-lysosome-fusion

GABARAP recruits PI4KIIα to autophagosomes. Depletion of either GABARAP or PI4KIIα by siRNA, or overexpression of the dominant negative kinase-dead PI4KIIα, blocks autophagic flux by inhibiting autophagosome fusion with lysosomes to generate grossly enlarged autophagosomes.

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