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People | Cowell Lab | UT Southwestern, Dallas, Texas

https://labs.utsouthwestern.edu/cowell-lab/people

Get to know our Principal Investigator and team of researchers at Cowell Lab.

Endothelial Mechanisms Contributing to Type 2 Diabetes Development | Shaul / Mineo Lab | UT Southwestern, Dallas, Texas

https://labs.utsouthwestern.edu/shaul-mineo-lab/research/endothelial-mechanisms-contributing-type-2-diabetes-development

Endothelial Mechanisms Contributing to Type 2 Diabetes Development

Gelsolin regulates the actin cytoskeleton and membrane signaling | Yin Lab | UT Southwestern, Dallas, Texas

https://labs.utsouthwestern.edu/yin-helen-lab/research/gelsolin-regulates-actin-cytoskeleton-and-membrane-signaling

We now want to know how gelsolin and gelsolin-like proteins behave in living cells. We are developing a fluorescence energy transfer reporter to monitor gelsolin activation in live cells.

Phosphoinositide regulation of Golgi functions | Yin Lab | UT Southwestern, Dallas, Texas

https://labs.utsouthwestern.edu/yin-helen-lab/research/phosphoinositide-regulation-golgi-functions

We have found that PI4P is essential for recruitment of adaptor coat proteins to the Golgi and propose that PI4P helps establish the Golgi's unique organelle identify.

People | Yin Lab | UT Southwestern, Dallas, Texas

https://labs.utsouthwestern.edu/yin-lab/people

Get to know our Principal Investigator and team of researchers at Helen Yin Lab.

Research | Yin Lab | UT Southwestern, Dallas, Texas

https://labs.utsouthwestern.edu/yin-helen-lab/research

We focus on the lipid kinases that synthesize PIP2 (phosphatidylinositol phosphate 5 kinases, PIP5Ks) and PI4P (phosphatidylinositol 4 kinases, PI4Ks), as well as the regulatory proteins that respond to PIP2 and PI4P. 

Endothelial Underpinnings of Atherosclerosis | Shaul / Mineo Lab | UT Southwestern, Dallas, Texas

https://labs.utsouthwestern.edu/shaul-mineo-lab/research/endothelial-underpinnings-atherosclerosis

Endothelial Underpinnings of Atherosclerosis

Publications | Napierala Lab | UT Southwestern, Dallas, Texas

https://labs.utsouthwestern.edu/napierala-lab/publications

Napierala Lab Publications

Autophagosome: Lysosome fusion | Yin Lab | UT Southwestern, Dallas, Texas

https://labs.utsouthwestern.edu/yin-lab/yin-helen-lab/research/autophagosome-lysosome-fusion

GABARAP recruits PI4KIIα to autophagosomes. Depletion of either GABARAP or PI4KIIα by siRNA, or overexpression of the dominant negative kinase-dead PI4KIIα, blocks autophagic flux by inhibiting autophagosome fusion with lysosomes to generate grossly enlarged autophagosomes.

Cell Line Repository | Napierala Lab | UT Southwestern, Dallas, Texas

https://labs.utsouthwestern.edu/napierala-lab/cell-line-repository

See the Napierala Lab's research

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