Search
Meet the PI | Chung Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/chung-lab/people/meet-pi
Meet our Principal Investigator, Stephen Chung, M.D.
Research | Michaely Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/michaely-lab/research
Learn about the Michaely Lab's research.
News | Pan Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/pan-lab/news
Skip to main content News In the News Online Lectures
Contact Us | Michaely Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/michaely-lab/contact-us
Contact the Michaely Lab.
People | Cowell Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/cowell-lab/people
Get to know our Principal Investigator and team of researchers at Cowell Lab.
Autophagosome: Lysosome fusion | Yin Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/yin-lab/yin-helen-lab/research/autophagosome-lysosome-fusion
GABARAP recruits PI4KIIα to autophagosomes. Depletion of either GABARAP or PI4KIIα by siRNA, or overexpression of the dominant negative kinase-dead PI4KIIα, blocks autophagic flux by inhibiting autophagosome fusion with lysosomes to generate grossly enlarged autophagosomes.
Gelsolin regulates the actin cytoskeleton and membrane signaling | Yin Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/yin-helen-lab/research/gelsolin-regulates-actin-cytoskeleton-and-membrane-signaling
We now want to know how gelsolin and gelsolin-like proteins behave in living cells. We are developing a fluorescence energy transfer reporter to monitor gelsolin activation in live cells.
Research | Yin Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/yin-helen-lab/research
We focus on the lipid kinases that synthesize PIP2 (phosphatidylinositol phosphate 5 kinases, PIP5Ks) and PI4P (phosphatidylinositol 4 kinases, PI4Ks), as well as the regulatory proteins that respond to PIP2 and PI4P.
PIP2 regulates the actin cytoskeleton and vesicle transport | Yin Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/yin-lab/yin-helen-lab/research/pip2-regulates-actin-cytoskeleton-and-vesicle-transport
We are studying how these molecules work together to generate comets, and defining how actin contributes to vesicle traffic.
Endothelial Mechanisms Contributing to Type 2 Diabetes Development | Shaul / Mineo Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/shaul-mineo-lab/research/endothelial-mechanisms-contributing-type-2-diabetes-development
Endothelial Mechanisms Contributing to Type 2 Diabetes Development