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In our lab, we focus on the mechanisms of cerebrovascular reactivity, exploring how blood vessels in the brain respond to changes in carbon dioxide, blood pressure, and other stimuli. 

The Tatara Laboratory applies engineering technologies to study and treat infectious diseases. We are particularly engaged in device-related infection, orthopedic immunology, and pathogen virulence on biomaterial surfaces. 

Our lab specializes in clinical and research informatics, with a diverse portfolio of projects that leverage electronic health record (EHR) data and multimodal research data to enhance clinical care and advance research in the neurosciences.

The Leavey Lab focuses on clinical and translational trials in pediatric sarcoma.

Skip to main content Publications Structural basis for substrate selectivity by site-one protease revealed by studies with a small molecule inhibitor . Bullington AV , Micallo I, Bajaj B , Kumar P , Schlamowitz N , Silva A , Hendrix S, Zelcer N*, and Kober DL * . PNAS (2025). *Co-corresponding author…

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Interventional psychiatry is treatment that combines brain stimulation with medication for difficult-to-treat mental health disorders. At UT Southwestern Medical Center, our psychiatrists have advanced training and expertise in caring for people with treatment-resistant mental health disorders.We specialize in the latest advances in brain stimulation to bring relief to people who haven’t had success with traditional treatments.

Skip to main content Research What is Ubiquitin? Ubiquitin is a small eukaryotic protein that is attached to aberrant proteins and promotes their degradation as a form of protein quality control. Ubiquitin is first bound by a ubiquitin activating enzyme (E1) in an ATP-dependent manner and transferred…

Skip to main content Team Jeon Lee, Ph.D. (Director) Since December 2020, Jeon Lee has been appointed as an Assistant Professor in the Lyda Hill Department of Bioinformatics. He received his Ph.D. in Biomedical Engineering from Yonsei University in South Korea (1999–2006), where he trained as a medic…

The Louros Lab uses a hybrid approach combining molecular biophysics, structural biology, and bioinformatics to investigate protein stability, misfolding, and aggregation, with a particular interest in neurodegenerative diseases.