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Skip to main content Research The Tatara Laboratory investigates the host/pathogen/material interface of device-related infection. Implantable devices, such as joint replacements and pacemakers, improve the lives of many patients. However, these devices are more susceptible to infection than native t…

The Molecular Imaging and Precision Medicine Lab has four Technology Research and Development (TR&D) projects that provide a platform on which new technology is developed and disseminated. The TR&Ds are complementary and integrated and extend from the development of reagents to detect and promote an immune reactive tumor microenvironment to the synthesis of nanodrones to treat cancer and combined small-molecule diagnostic and therapeutics (theranostic agents). We focus on generation of next-generation precision platforms, tools and techniques for tackling problems at the forefront of biomedical research with a focus on those that will lead to near-term translation.

Zhu (Yuan) Lab Members

Skip to main content Neural-crest Stem Cells and Malignant Peripheral Nerve Sheath Tumor (MPNST) MPNST, a sarcoma arising from the neural-crest stem cell lineage in the peripheral nerve, is the leading cause of death for individuals with NF1. The presence of benign and premalignant lesions, namely, p…

Skip to main content Developing Neural Stem Cells and Pediatric Brain Tumors Pediatric low-grade gliomas (pLGGs) are the most common brain tumors in children, but rarely occur in adulthood. Genetically, pLGGs are a single molecular disease universally driven by abnormal activation of the RAS-RAF-MEK-…

In our lab, we focus on the mechanisms of cerebrovascular reactivity, exploring how blood vessels in the brain respond to changes in carbon dioxide, blood pressure, and other stimuli. 

In the Suleiman Lab, we focus on studying the podocyte biology, specifically the actin dynamics and cytoskeleton. Our research includes examining the balance of Rac and RhoA, two members of the Rho small GTPases, in both healthy and diseased kidneys. 

Engineered hydrogel biomaterials to improve tissue regeneration and disease modelling

The Leavey Lab focuses on clinical and translational trials in pediatric sarcoma.

Skip to main content Meet the Team Makoto Ishii, M.D., Ph.D. Principal Investigator & Assistant Professor Dr. Makoto Ishii is a board-certified neurologist and a physician-scientist dedicated to both patient care and biomedical research focusing primarily on Alzheimer’s disease and related neurodegen…