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Skip to main content Key Projects Pharmacologic Suppression of B7-H4 Glycosylation Restores Antitumor Immunity in Immune-Cold Breast Cancers Despite widespread utilization of immunotherapy, treating immune-cold tumors has proved to be a challenge. Here, we report that expression of the immune checkpo…

Skip to main content Publications Chen X, Song X , Li J, Zhang R, Yu C, Zhou Z, Liu J, Liao S, Klionsky DJ, Kroemer G, Liu J, Tang D, Kang R. Identification of HPCAL1 as a specific autophagy receptor involved in ferroptosis. Autophagy. 2023 Jan;19(1): 54-74. doi:10.1080/15548627.2022.2059170. Epub 20…

Skip to main content Our Collaborators Ken Westover, M.D., Ph.D. Westover Lab Read more about the Westover Lab Daolin Tang, M.D., Ph.D. Tang Lab Read more about the Tang Lab Rui Kang, M.D., Ph.D. See Dr. Kang's profile Herbert J. Zeh, III, M.D. See Dr. Zeh's profile Yong Lee, Ph.D. See Dr. Lee's prof…

Skip to main content Research Dynamics of cytosolic and mitochondrial translation Coordinated gene expression from the nuclear and mitochondrial genomes is pivotal for cellular homeostasis. Consequently, dysregulated protein synthesis in either compartment is linked to human diseases. Our major goal …

Skip to main content Lab Alumni Nigel Cole Summer Student Nigel grew up and reside in Dallas, Texas, and is currently pursuing a Bachelor of Science in Agricultural Business with a minor in Data Analytics Systems at Southern University and A&M College. For the past two summers, he has worked in the O…

Skip to main content Join Us We are hiring at all levels! Join us to build a diverse, interdisciplinary research team! Graduate students Please email Jinfan to set up a time to chat about potential research projects. Technicians/Postdocs/Scientists Please email Jinfan with an updated CV and a brief c…

Skip to main content Join Our Lab Reach Out! The Galia lab is currently recruiting motivated Postdocs and Ph.D. students . If you are interested in joining our team, please send a cover letter, CV, and contact information for 3 references to Dr. Galia! Email : liraz.galia@utsouthwestern.edu Office Ph…

All publications (# equal contribution):24. Choreography of human mitochondrial leaderless mRNA translation initiation. Shen S, Xu Y, Kober DL, Wang J. bioRxiv [Preprint]. 2025 Jul 10:2025.07.10.662049. doi: 10.1101/2025.07.10.662049.23. Real-time detection of human telomerase DNA synthesis by multiplexed single-molecule FRET. Hentschel J, Badstübner M, Choi J, Bagshaw CR, Lapointe CP, Wang J, Jansson LI, Puglisi JD, Stone MD. Biophys. J. 2023, 122, 3447-3457.22. Dynamics of release factor recycling during translation termination in bacteria. Prabhakar A, Pavlov MY, Zhang J, Indrisiunaite G, Wang J, Lawson MR, Ehrenberg M, Puglisi JD. Nucleic Acids Res. 2023, 51, 5774-5790.21. Rapid 40S scanning and its regulation by mRNA structure during eukaryotic translation initiation. Wang J, Shin BS, Alvarado C, Kim JR, Bohlen J, Dever TE, Puglisi JD. Cell 2022, 185, 4474-4487.e17.20. eIF5B and eIF1A reorient initiator tRNA to allow ribosomal subunit joining. Lapointe CP, Grosely R, Sokabe M, Alvarado C, Wang J…

Skip to main content Research My lab's research is focused on the following areas: Promoting Nerve Regeneration In general, injured axons in the central nervous system fail to regenerate. There are yet no therapies for promoting axon regeneration once the damage is done. In recent years much progress…

Skip to main content Publications Featured Publications Solmonson A, Faubert B, Gu W, Rao A, Cowdin MA, Menendez-Montes I, Kelekar S, Rogers TJ, Pan C, Guevara G, Tarangelo A, Zacharias LG, Martin-Sandoval MS, Do D, Pachnis P, Dumesnil D, Mathews TP, Tasdogan A, Pham A, Cai L, Zhao Z, Ni M, Cleaver O…