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A molecule has demonstrated its ability to kill tumor cells and incite an immune response in preclinical models of small cell lung cancer (SCLC), according to UT Southwestern Medical Center researchers.

Automated external defibrillators (AEDs) are underutilized during cardiac arrest episodes despite laws in some states requiring their availability in high-risk areas such as athletic facilities, researchers at UT Southwestern Medical Center found. The devices can save lives by shocking the heart back into normal rhythm.

UT Southwestern Medical Center is collaborating with Pfizer Inc. to develop RNA enhanced delivery technologies for genetic medicine therapies through the Dallas-based medical center’s Program in Genetic Drug Engineering.

A nanoparticle-based therapy developed by UT Southwestern Medical Center scientists stimulated an immune pathway that eradicated tumors in mouse models of various cancer types.

UT Southwestern Medical Center researchers have identified an experimental molecular compound that significantly improved survival among cellular models and mouse models of amyotrophic lateral sclerosis (ALS), the fatal neurodegenerative disease.

A UT Southwestern Medical Center study of hundreds of underserved women showed that depression and anxiety, in addition to physical factors such as a higher body mass index and previous births, are associated with lingering postpartum urinary incontinence. The findings, published in Urogynecology, shine a spotlight on these conditions that can carry stigmas but are largely treatable, researchers say.

Patients with fibromyalgia and irritable bowel syndrome (IBS) who take multiple medications are more likely to develop severe drug intolerance than healthy patients, UT Southwestern Medical Center researchers reported.

Exercising at a high level doesn’t affect the progression of calcium buildup in the arteries, even among older athletes such as marathoners who tend to have higher coronary artery calcium (CAC) scores, according to new research from UT Southwestern Medical Center.

Researchers at UT Southwestern Medical Center developed nanoparticles that successfully edited the disease-causing gene in the lungs of a mouse model of cystic fibrosis (CF), swapping a mutated form for a healthy one that persisted in stem cells. Their findings, reported in Science, could offer hope for people with CF and other debilitating genetic lung diseases.

Nutritious meal kits and no-prep meals improved food security and perceived dietary quality among clients of a Dallas food pantry, according to a pilot study led by UT Southwestern Medical Center.