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Findings may move science closer to growing organs in other species: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/dec-growing-organs-other-species.html

Failure of human pluripotent stem cells (PSCs) to survive when grown with the PSCs of distantly related species occurs because of an innate immune reaction in the nonhuman cells, a study led by UT Southwestern Medical Center researchers suggests.

Rare genetic disorder linked to liver dysfunction, hypoglycemia, lipodystrophy : Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/dec-rare-genetic-disorder-hypoglycemia.html

A rare genetic disorder discovered by UT Southwestern Medical Center researchers and their colleagues can cause brain damage from dangerously low blood sugar levels and liver damage in infants, along with variable body fat loss, fatty tumors, and metabolic complications in youth and adults.

Maternal Health Accelerator raises nearly $25 million to improve maternal morbidity rates in North Texas: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/nov-mha-maternal-morbidity-rates.html

The Anne Burnett Marion School of Medicine at Texas Christian University and UT Southwestern Medical Center have joined forces to address some of the highest maternal morbidity rates in the country by forming the North Texas Maternal Health Accelerator (MHA).

Presurgical vaccine may prevent orthopedic device infections: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/dec-presurgical-vaccine-orthopedic-device-infections.html

A UT Southwestern Medical Center researcher and his colleagues developed a novel presurgical vaccine strategy that may prevent dangerous infections in patients receiving hip, knee, and other joint replacements.

Study reveals molecular ‘switch’ that turns on inflammation in obesity: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2026/jan-molecular-switch-inflammation-obesity.html

A team led by UT Southwestern Medical Center researchers has uncovered a molecular pathway that links obesity to widespread inflammation, providing long-sought insight into why obesity increases the risk of Type 2 diabetes, cardiovascular disease, fatty liver disease, and certain cancers.

Modified tau thwarts aggregation in neurodegenerative disease: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/dec-tau-thwarts-aggregation-neurodegenerative-disease.html

A designer version of the tau protein, developed by a team led by UT Southwestern Medical Center researchers, maintains its biological function while resisting aggregation, a pathological trait linked to neurodegenerative diseases called tauopathies.

UTSW researchers boost the power of CAR T cells to fight cancer : Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2026/jan-car-t-cell-to-fight-cancer.html

UT Southwestern Medical Center researchers have discovered that increasing the levels of a protein called BACH2 makes engineered cancer-fighting immune cells behave more like stem cells, improving their therapeutic effectiveness.

UT Southwestern helps advance state, national efforts to strengthen nutrition education in medical schools: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2026/march-strengthen-nutrition-education-in-medical-schools.html

– UT Southwestern, one of the first medical schools in the country to integrate culinary medicine and nutrition education into its curriculum, is partnering with the U.S. Department of Health and Human Services (HHS) and more than 50 other top medical schools to launch a program promoting more widespread, meaningful nutrition training for future doctors.

Social media may heighten depression severity in youth : Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/march-social-media-youth-depression.html

An emotional overattachment to social media may be associated with increased severity of mental health symptoms among young people being treated for depression, anxiety, and suicidal thoughts, according to researchers at UT Southwestern Medical Center.

UT Southwestern pharmacologists earn Hill Prize from TAMEST: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2025/jan-hill-prize-from-tamest.html

David Mangelsdorf, Ph.D., Chair and Professor of Pharmacology and Professor of Biochemistry at UT Southwestern Medical Center, has been awarded the Hill Prize in Biological Sciences from the Texas Academy of Medicine, Engineering, Science and Technology (TAMEST) in recognition of his long-standing research on orphan nuclear receptors – proteins in the cell nucleus that flip genes on and off and are triggered by unknown molecules.