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– In a groundbreaking phase one clinical trial led by UT Southwestern Medical Center, a short interfering RNA (siRNA) drug directed to tumor cells, ARO-HIF2, effectively disrupted HIF2α, a key driver of clear cell renal cell carcinoma (ccRCC).

Vincent Tagliabracci, Ph.D., Associate Professor of Molecular Biology at UT Southwestern Medical Center, will receive the 2024 Edith and Peter O’Donnell Award in Biological Sciences from the Texas Academy of Medicine, Engineering, Science and Technology (TAMEST) for broadening the understanding of pseudokinases, a family of enzymes that play key roles in many physiological and pathological processes.

UT Southwestern Medical Center joined leaders in Dallas and across the nation in mourning the loss and honoring the legacy of U.S. Rep. Eddie Bernice Johnson, an inspirational leader who helped advance the medical center’s science, research, clinical care, and educational initiatives during her extraordinary career representing the area.

ChatGPT, the artificial intelligence (AI) chatbot designed to assist with language-based tasks, can effectively extract data for research purposes from physicians’ clinical notes, UT Southwestern Medical Center researchers report in a new study.

Surgical nerve decompression, used to treat conditions such as carpal tunnel syndrome and sciatica, could play a role in relieving the pain of diabetic neuropathy patients, researchers at UT Southwestern Medical Center found.

UT Southwestern Medical Center has joined more than a dozen leading medical centers and Microsoft to form the Trustworthy & Responsible AI Network (TRAIN), a national group designed to set standards and safely explore applications of artificial intelligence (AI) in health care.

Children's HealthSM and UT Southwestern Medical Center on Wednesday announced a historic gift of $100 million from the Jean and Mack Pogue family in support of the $5 billion transformative new Dallas pediatric campus, unveiled earlier this year. The gift from the Pogue Foundation is one of only four $100 million philanthropic gifts ever publicly announced in North Texas, and it is the largest donation yet to the new pediatric campus project, which will replace the existing Children’s Medical Center Dallas.

Nine scientists and physicians in the Harold C. Simmons Comprehensive Cancer Center at UT Southwestern Medical Center have been awarded nearly $13 million in grants from the Cancer Prevention and Research Institute of Texas (CPRIT) to support research and prevention efforts on a wide range of cancer issues.

Thyrotoxic periodic paralysis (TPP), a rare neurological condition causing limbs to go limp, may be an underrecognized cause of paralysis in young Hispanic men, a review of data by UT Southwestern endocrinologists shows.

With new cases of malaria being reported in Texas and Florida, researchers at UT Southwestern Medical Center continue to explore compounds for more effective drug-resistant therapies and biological targets to interfere with the parasites that spread the potentially fatal disease.