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Muto lab leverages both cutting-edge wet-lab and multi-omics approaches to understand gene regulatory mechanism driving kidney diseases. Current projects are focused on acute kidney injury and polycystic kidney disease.

Skip to main content News August 19 2026 AHA Scientific Sessions 2026 Abstract Accepted: Targeted mTOR Suppression with Optoacoustic Imaging for Myocardial Ischemia/Reperfusion Injury Our abstract "Targeted mTOR Suppression Using a Novel Optoacoustic Imaging Strategy Improves Myocardial Ischemia/Repe…

Skip to main content Join the Team Mentoring the next generation of clinicians, scientists, and students is an essential part of our research program. We are always interested in having dedicated scientists join our research laboratory, particularly students. Please send your CV for consideration | E…

Skip to main content Research Alzheimer's disease is the most common cause of dementia in the elderly and remains a devastating disease with currently no cure and limited therapeutic options. The exact pathogenesis of Alzheimer’s disease is being actively investigated, but a leading hypothesis is tha…

Dr. Kang's research is dedicated to elucidating the molecular and immunological roles of damage-associated molecular patterns (DAMPs) and pattern recognition receptors (PRRs) in inflammatory diseases. 

The Molecular Imaging and Precision Medicine Lab has four Technology Research and Development (TR&D) projects that provide a platform on which new technology is developed and disseminated. The TR&Ds are complementary and integrated and extend from the development of reagents to detect and promote an immune reactive tumor microenvironment to the synthesis of nanodrones to treat cancer and combined small-molecule diagnostic and therapeutics (theranostic agents). We focus on generation of next-generation precision platforms, tools and techniques for tackling problems at the forefront of biomedical research with a focus on those that will lead to near-term translation.

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Skip to main content Neural-crest Stem Cells and Malignant Peripheral Nerve Sheath Tumor (MPNST) MPNST, a sarcoma arising from the neural-crest stem cell lineage in the peripheral nerve, is the leading cause of death for individuals with NF1. The presence of benign and premalignant lesions, namely, p…

Skip to main content NF1-associated Autism (NF1-Autism) – Non-cancer Manifestations with TGS Syndromes Approximately 40%-70% of children with NF1 exhibit one or more forms of specific learning disabilities and 20%-45% have the features of autistic spectrum disorder (ASD). Thus, NF1 represents a uniqu…

Skip to main content Meet the Team Makoto Ishii, M.D., Ph.D. Principal Investigator & Assistant Professor Dr. Makoto Ishii is a board-certified neurologist and a physician-scientist dedicated to both patient care and biomedical research focusing primarily on Alzheimer’s disease and related neurodegen…