Search

We research the involvement of post-translational modifications (such as ubiquitination, glycosylation) in glycogen biology and its role in glycogen metabolism related neurological and neuromuscular diseases. We also aim to develop appropriate therapies against these diseases using cutting-edge technologies such as gene therapy.

We anticipate this work to enhance functional recovery and improve the quality of life for trauma patients, while advancing our understanding of HO pathogenesis and normal tissue response to radiation.

Skip to main content Lab Fun Laser tag (victorious vs the Nam lab!) Out in nature on a hike First group picture! Spring 2023 We moved down the hall! Don't look directly at the sun! Summer 2024 Taking at break from science to check out the birds (retreat 2024) Lab in summer 2023 Halloween 2024 Join Ou…

The Wang Lab investigates the roles of genetic factors and transcriptional regulation in skeletal diseases and bone cancer.

Engineered hydrogel biomaterials to improve tissue regeneration and disease modelling.

Skip to main content Publications Structural basis for substrate selectivity by site-one protease revealed by studies with a small molecule inhibitor . Bullington AV , Micallo I, Bajaj B , Kumar P , Schlamowitz N , Silva A , Hendrix S, Zelcer N*, and Kober DL * . PNAS (2025). *Co-corresponding author…

The Wang (Jui-Kai) Lab is dedicated to advancing the intersection of ophthalmology, image processing, and artificial intelligence. 

Skip to main content Lab Members Hua-Kang Wu, Ph.D. Research Scientist Hua-Kang earned his Ph.D. in Immuno-hematology from the University of Tokyo, Japan. He completed his postdoctoral training in Molecular Cancer Genetics at the University of Toronto, Canada, and gained further scientific experience…

Recent work from our laboratory and others has demonstrated that radiation effectively modifies the microenvironmental metabolism, subsequently influencing DNA damage repair responses. 

Meet the Sharma Lab team