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Skip to main content Research Goal: Create novel immunotherapy that suppresses inflammatory immune reactions and enhances cancer immunity. Objectives : Understand cellular and molecular mechanisms that regulate immune responses. Find novel biomarkers and new therapeutic targets for treating skin infl…

Skip to main content News February 2024 Research Assistant II Opportunity We are currently seeking a qualified and motivated individual to join our esteemed research team at UTSW Medical Center. As a Research Assistant II, you will play a pivotal role in supporting our scientific endeavors, contribut…

In the Izumi Lab, with the ultimate goal of identifying druggable molecules/pathways in pediatric genetic disorders, we investigate the molecular mechanisms of pediatric genetic disorders due to chromosomal abnormalities and chromatin protein mutations. We employ novel genetic approaches by using patient-derived samples, induced pluripotent stem cell models and mutant mouse models.

Skip to main content Publications Phase II Trial of Sipuleucel-T and Stereotactic Ablative Body Radiation for Patients with Metastatic Castrate-Resistant Prostate Cancer Hannan R, Dohopolski MJ, Pop LM, Mannala S, Watumull L, Mathews D, Gao A, Garant A, Arriaga YE, Bowman I, Chung J-S, Wang J, Ariizu…

Skip to main content Cerebral Autoregulation, Brain Perfusion, and Neurocognitive outcomes after Traumatic Brain Injury (CAPCOG-TBI) The focus of this study is to determine whether neurodegeneration and cognitive outcomes change after a year following a moderate to severe traumatic brain injury (TBI)…

Publications for Dr. Lin

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Skip to main content Contact Us Irene Dougherty Research Associate/Lab Manager Contacts Email Address: irene.dougherty@utsouthwestern.edu Lab Number: 214-648-3084 Mailing Address 5323 Harry Hines Blvd., Dallas, TX 75390 Physical Address 6000 Harry Hines Blvd., Dallas, TX 75235

Dr. LoBue's BRAIN lab, short for Brain Aging, Injury, and Modulation Lab, has two lines of research in the area of aging and neurodegenerative diseases. The lab investigates the later-in-life effects of traumatic brain injury, which involves understanding the potential risk associated with developing dementia and the underlying biological pathways. The lab also studies the effects of noninvasive brain stimulation in Alzheimer’s disease and related disorders with the goal of informing the development of new treatments.

Skip to main content Publications Featured Publications: Mechanisms and pathology of protein misfolding and aggregation. Louros N, et . Nature Rev. Mol. Cell Biol. 24(12): 912-933. (2023) Medin promotes vascular amyloid-β aggregation in Alzheimer’s disease. Wagner J, et al. Nature 612, 123-131 . (202…