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Zhu (Yuan) Lab Members

The Liu Lab studies the seasonal clock and its roles in human health. We use a new seasonal primate model, the mouse lemur, and an interdisciplinary approach of molecular biology, genetics, omics, machine learning, and computational modeling. We also apply the mouse lemur primate model to study pathophysiology that is poorly represented in mice, with a focus on neurodegeneration, immunology, and metabolism.

The Singal & Rich research group focuses on generating critical insights to improve the entire spectrum of liver cancer care. Our studies involve assessing and promoting novel practices, imaging, and blood-based biomarkers to improve risk stratification, screening, early detection and outcomes for patients with hepatocellular carcinoma and other primary liver cancers.  

Research lab at UT Southwestern for Mohan Krishnan, Ph.D.

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Skip to main content Adult Neural Stem Cells and High-grade Glioma and Glioblastoma (GBM) GBM is the most common primary brain tumor in adults with no pre-existing lower-grade lesions. The rapid clinical course of adult GBMs presents a major challenge to develop a preventive therapy. A recent study r…

Skip to main content NF1-associated Autism (NF1-Autism) – Non-cancer Manifestations with TGS Syndromes Approximately 40%-70% of children with NF1 exhibit one or more forms of specific learning disabilities and 20%-45% have the features of autistic spectrum disorder (ASD). Thus, NF1 represents a uniqu…

Skip to main content Meet the Team Makoto Ishii, M.D., Ph.D. Principal Investigator & Assistant Professor Dr. Makoto Ishii is a board-certified neurologist and a physician-scientist dedicated to both patient care and biomedical research focusing primarily on Alzheimer’s disease and related neurodegen…

Skip to main content Meet the PI Matthew Sun, M.D. Matthew Sun, MD, is an Assistant Professor in the Department of Neurosurgery. He specializes in the treatment of brain tumors with a special interest in skull base pathologies. He earned his medical degree at University of California San Francisco. H…

Skip to main content Neural-crest Stem Cells and Malignant Peripheral Nerve Sheath Tumor (MPNST) MPNST, a sarcoma arising from the neural-crest stem cell lineage in the peripheral nerve, is the leading cause of death for individuals with NF1. The presence of benign and premalignant lesions, namely, p…