Search

Skip to main content DAB2IP and Chromosome Stability Defects in kinetochore-microtubule (KT-MT) attachment and the spindle assembly checkpoint (SAC) during cell division are strongly associated with chromosomal instability. Chromosomal instability has been linked to carcinogenesis, metastasis, poor p…

Skip to main content Meet the PI Debabrata Saha, Ph.D. Debabrata Saha, Ph.D. began his research career at the University of Nebraska, Lincoln, as a graduate student and received his Ph.D. in chemistry studying eukaryotic protein synthesis initiation in the laboratory of late Professor Naba K. Gupta. …

Wei Xu Lab strives to achieve a mechanistic understanding of fundamental cognitive processes, explore their impairments in neuropsychiatric disorders, and discover innovative treatments for these conditions. 

Qin Lab focuses on the development of novel synthetic transformations and strategies that will allow access to bioactive, complex natural products and efficient synthesis of pharmaceuticals and their derivatives.

Dr. Gray is overseeing one of the nation’s few facilities that manufactures a special type of gene-delivering virus for patient use.

Skip to main content Designing a Novel Drug-Delivery System The Saha Lab is designing a novel drug-delivery system that will release potent radiosensitizer and/or chemotherapeutic agents to lung and prostate tumors to enhance the efficacy of combined modality therapy. This project is an ongoing colla…

Located in the Department of Ophthalmology, the Wert laboratory studies the post-mitotic neuronal cells of the retina, particularly the photoreceptor cells. Our goal is to discover and understand the mechanisms underlying retinal degenerative disease, and to provide novel therapeutics for these complex degenerative disorders using gene therapy and genome engineering technologies, human stem cell transplantations, and metabolic rescue.

Limbworks - Basic and Translational Research Peripheral Nerve LabOur lab performs a comprehensive suite of outcome measures to assess peripheral nerve regeneration and chronic neural interfacing in the research setting.

Skip to main content Research 1. Roles of membrane contact sites in intracellular lipid trafficking and homeostasis in response to cellular stress. Membrane contact sites (MCSs) are regions where signals and small molecules, such as lipids, are exchanged between organelles. The Prinz lab studies the …

The Bailey lab focuses on developing gene therapies for neurological disorders. We work on monogenetic pediatric disorders, including SLC13A5 epileptic encephalopathy, multiple sulfatase deficiency, Charcot Marie Tooth disease type 4J, giant axonal neuropathy and ECHS1 deficiency.