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Our current research is focused on biochemical and structural studies of how membrane molecules signal to the actin cytoskeleton through a large, five-protein complex named the WAVE Regulatory Complex (WRC). 

Skip to main content Research Cristae Organization Positioning of mitochondrial cristae and functions of the MICOS complex Cristae membranes are the hallmark feature of mitochondria, giving them their distinctive appearance in electron microscopy images. Cristae are home to the respiratory complexes …

Skip to main content Lab Members Meet the Principal Investigator William T. Dauer, M.D. Director, Peter O'Donnell Jr. Brain Institute Lois C.A. and Darwin E. Smith Distinguished Chair in Neurological Mobility Research Department of Neurology Department of Neuroscience UT Southwestern Medical Center E…

Skip to main content Contact Us Matthew Mitsche, Ph.D. Assistant Professor Center for Human Nutrition Molecular Genetics Phone: 214-648-6614 Email Mailing Address UT Southwestern Medical Center 5323 Harry Hines Blvd. K5.140 Dallas, Texas 75390-9014

Skip to main content Publications Kim S, Phan S, Tran HT, Shaw TR, Shahmoradian SH, Ellisman MH, Veatch SL, Barmada SJ, Pappas SS, Dauer WT. TorsinA is essential for neuronal nuclear pore complex localization and maturation. Nat Cell Biol. 2024 Sep;26(9):1482-1495. doi: 10.1038/s41556-024-01480-1. Ep…

We have two major areas of research: respiratory viruses and newly emerging pathogens. 

The Jiang Lab studies ion channels.

Ming-Chang Hu Lab strives to offer novel insight into the cellular and molecular mechanisms of AKI progression to CKD and cardiovascular diseases (vascular calcification and uremic cardiomyopathy) development in CKD, and set up a solid basis for preclinical and clinical study in the future.

Chen Lab is broadly interested in mechanisms of signal transduction, namely how a cell communicates with its surroundings and within itself.

Current Research projects in the Cardiometabolic Research Unit