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Research | LoBue Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/lobue-lab/research
Get involved in the Brain Aging, Injury, and Modulation Lab's research by participating in a study.
Pfeiffer (Brad) Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/pfeiffer-brad-lab
The Pfeiffer Lab is interested in how the brain forms neural representations of experience, how those representations are consolidated into long-term memory, and how those representations can be later recalled to inform behavior.
Bachoo Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/bachoo-lab
The Neuro-Oncology Translational Research Laboratory studies primary brain tumors from pure basic science through the continuum to clinical trials.
Osborne Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/osborne-lab
The Osborne Lab focuses on how regulation of miRNA and mRNA controls the branching of developing cells, and how disregulation of these pathways contributes to aggressive tumor behavior.
Publications | LoBue Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/lobue-lab/publications
Publications of Brain Aging, Injury, and Modulation Lab
Arteaga Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/arteaga-lab
The Arteaga laboratory has a longstanding interest in understanding the molecular pathways that drive breast cancer progression and influence response to therapies.
Research Family | Yang Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/yang-lab/research-family
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Asch Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/asch-lab
The central goal of Dr. Asch's research is to uncover the mechanistic underpinnings of how stress and trauma affect brain function, with a particular emphasis on how these experiences shape mental health outcomes with the aim to contribute to the development of novel interventions designed to mitigate the harmful effects of stress and trauma, foster resilience, and ultimately improve overall health and well-being.
Hobbs-Cohen Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/hobbs-cohen-lab
Our research program focuses on understanding how dysregulation of lipid uptake and trafficking contributes to human diseases.
Wang (Fei) Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/wang-fei-lab
The broad research interest of Fei Wang lab is in dissecting molecular mechanisms of essential cellular events in eukaryotic cell development. Currently, my laboratory investigates how cells preserve the fidelity of gametogenesis under environmental and physiological stress. Gametogenesis, the process by which diploid precursors undergo meiosis and differentiation to produce haploid gametes, is remarkably sensitive to temperature and other stressors. Even mild perturbations tolerated by mitotically dividing cells can disrupt meiosis, leading to infertility or defective gametes. This heightened sensitivity reflects the competing demands faced by germ cells: they must complete complex developmental transitions while responding flexibly to environmental challenges. The mechanisms that safeguard meiotic integrity under such conditions have long remained poorly understood. In somatic cells, two conserved pathways—stress granules (SGs) and autophagy—serve as major quality-control systems under stress. SGs se…