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Through our expertise, our expert team is leading the charge to develop more effective alternate therapies for urinary tract infections.

Skip to main content Lipid Assembly Fatty liver disease is a growing epidemic that has no effective treatment strategies. To date, most genetic variants associated with fatty liver have a role in the assembly and biosynthesis of lipids. Our lab studies mouse models of genetic variants associated with…

Skip to main content About Us The Mitsche lab uses mass spectrometry and stable isotope labeling to understand the progression of metabolic syndrome, in particular fatty liver and cardiovascular disease. Our primary focus is understanding the link between alterations in fat composition disease. We ai…

The Vernino Lab focuses on the mechanisms of autoimmune disorders of the nervous system, especially those associated with neurological autoantibodies. We use a variety of techniques including histology, and immunology.  This research is complemented by clinical therapeutic trials studying novel treatments for autoimmune encephalitis and autonomic disorders.

Zhang (Chun-Li) Lab research focuses on cellular plasticity in the adult nervous system and modeling human neurodegenerative diseases. We use cell culture and genetically modified mice as model systems. Molecular, cellular, electrophysiological, and behavioral methods are employed.

The Wang Lab uses chemical biology tools to study the molecular mechanisms underlying interesting bacterial behaviors.

Skip to main content Flux Technology Measuring the rate of lipid biosynthesis has traditionally been done using radio-isotope labeling. While this technology is very sensitive, it is inherently dangerous due to the radioactivity and fairly non specific. Stable-isotope labeling provides an alternative…

Skip to main content Research Cristae Organization Positioning of mitochondrial cristae and functions of the MICOS complex Cristae membranes are the hallmark feature of mitochondria, giving them their distinctive appearance in electron microscopy images. Cristae are home to the respiratory complexes …

The Reddy Lab focuses on restoring effective antigen presentation to enhance anti-tumor immunity in breast cancers.

Dr. Wang's research interests primarily involve the development of statistical methodologies for the design and analysis of clinical trials, as well as the evaluation of correlated data and repeated measurements. Her specific focus has been on power analysis, experimental design, and sample size determination for longitudinal studies using Frequentist and Bayesian approaches. Dr. Wang has also developed the methodologies that are very flexible and can accommodate various pragmatic issues such as longitudinal and clustered outcomes, random variability in cluster size, unbalanced randomization, complicated correlation structures, missing data, and small sample sizes. Those methodologies have achieved great performances across a broad spectrum of design configurations and made innovative contributions to clinical studies.