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FEBS Letters 581 (2007) 2181–2193 Minireview Cell–cell fusion Elizabeth H. Chena, Eric Groteb, William Mohlerc, Agnès Vigneryd,*,1 a Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, 725 N. Wolfe Street, Baltimore, MD 21205, USA b Department of Biochemistr…

Requirement of the fusogenic micropeptide myomixer for muscle formation in zebrafish Jun Shia,b,1, Pengpeng Bia,b,c,1, Jimin Peid, Hui Lia,b,c, Nick V. Grishind,e, Rhonda Bassel-Dubya,b,c, Elizabeth H. Chena,b,2, and Eric N. Olsona,b,c,2 aDepartment of Molecular Biology, University of Texas Southwes…

Developmental Cell Article A Critical Function for the Actin Cytoskeleton in Targeted Exocytosis of Prefusion Vesicles during Myoblast Fusion Sangjoon Kim,1,2 Khurts Shilagardi,1,2 Shiliang Zhang,1,2 Sabrina N. Hong,1 Kristin L. Sens,1 Jinyan Bo,1 Guillermo A. Gonzalez,1 and Elizabeth H. Chen1,* 1 …

Cell, Vol. 114, 751–762, September 19, 2003, Copyright 2003 by Cell Press Control of Myoblast Fusion by a Guanine Nucleotide Exchange Factor, Loner, and Its Effector ARF6 regulators of myoblast fusion identified genetically in Drosophila are likely to provide insights into mammalian myogenesis, as…

Differential splicing and glycosylation of Apoer2 alters synaptic plasticity and fear learning Catherine R. Wasser1,2,*,>†, Irene Masiulis2,†, Murat S. Durakoglugil1,2, Courtney Lane- Donovan1,2, Xunde Xian1,2, Uwe Beffert2, Anandita Agarwala2, Robert E. Hammer3, and Joachim Herz1,2,4,5,* 1Center…

People & Ideas JCB • VOLUME 206 • NUMBER 5 • 2014576 M ost cells in the body are solo entities, self-contained within a cell membrane. But there are certain cases in which cells meld together. Skeletal muscle cells, for example, are multinucleate syncytia that form through the process o…

ARTICLE OPEN Lrp1 in osteoblasts controls osteoclast activity and protects against osteoporosis by limiting PDGF–RANKL signaling Alexander Bartelt1,2,8, Friederike Behler-Janbeck1,2, F. Timo Beil1,3, Till Koehne3,4, Brigitte Müller1,2, Tobias Schmidt1,2, Markus Heine2,5, Laura Ochs1,2, Tayfun Yilmaz…

Article Mechanical Tension Drives Cell Membrane Fusion Graphical Abstract Highlights d Invasive protrusions trigger a mechanosensory response in a cell-fusion partner d Mechanosensory function of MyoII directs its accumulation at the fusogenic synapse d MyoII increases cortical tension and promo…

1Scientific RePorTS | (2018) 8:4501 | DOI:10.1038/s41598-018-22819-3 www.nature.com/scientificreports Loss of the adaptor protein ShcA in endothelial cells protects against monocyte macrophage adhesion, LDL-oxydation, and atherosclerotic lesion formation Antoine Abou-Jaoude1, Lise Badiqué1, Moh…