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Intratumoral Delivery of B-Lapachone via Polymer Implants for Prostate Cancer Therapy Ying Dong,1Shook-Fong Chin,1Elvin Blanco,1Erik A. Bey,1Wareef Kabbani,2 Xian-Jin Xie,1,3 William G. Bornmann,4 David A. Boothman,1andJinming Gao1 Abstract Purpose: h-Lapachone (ARQ 501, a formulation of h-lapachon…

Multifunctional Polymeric Micelles as Cancer-Targeted, MRI-Ultrasensitive Drug Delivery Systems Norased Nasongkla, † Erik Bey, † Jimin Ren, ‡ Hua Ai, † Chalermchai Khemtong, † Jagadeesh Setti Guthi, † Shook-Fong Chin, † A. Dean Sherry, ‡ David A. Boothman, † and Jinming Gao* ,† Simmons Comprehensi…

JOURNAL OF CELLULAR PHYSIOLOGY 209:604–610 (2006) Mornings With Art, Lessons Learned: Feedback Regulation, Restriction Threshold Biology, and Redundancy Govern Molecular Stress Responses ERIK A. BEY, SHELLY M. WUERZBERGER-DAVIS, JOHN J. PINK, CHIN-RANG YANG, SHINAKO ARAKI, KATHRYN E. REINICKE, MEL…

Available online at www.sciencedirect.com e 124 (2007) 11–19 www.elsevier.com/locate/jconrel Journal of Controlled Releas Modeling doxorubicin transport to improve intratumoral drug delivery to RF ablated tumors Brent D. Weinberg a,c, Ravi B. Patel a, Agata A. Exner b, Gerald M. Saidel a, Jinming G…

Modulating b-Lapachone Release from Polymer Millirods through Cyclodextrin Complexation FANGJING WANG,1 ELVIN BLANCO,2 HUA AI,3 DAVID A. BOOTHMAN,2 JINMING GAO2 1Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio 44106-7207 2Simmons Comprehensive Cancer Center, …

Antitumor efficacy and local distribution of doxorubicin via intratumoral delivery from polymer millirods Brent D. Weinberg,1 Hua Ai,2 Elvin Blanco,3 James M. Anderson,4 Jinming Gao3 1Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio 44106 2National Engineering R…

Poly(D, L-lactide-co-glycolide)/Poly(ethylenimine) Blend Matrix System for pH Sensitive Drug Delivery Damon Sutton, Remy Durand, Xintao Shuai,† Jinming Gao* Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio 44106 Received 29 April 2005; accepted 14 July 2005 DO…

119 (2007) 111–120 www.elsevier.com/locate/jconrel Journal of Controlled Release A mechanistic model of controlled drug release from polymer millirods: Effects of excipients and complex binding Fangjing Wang a, Gerald M. Saidel a,⁎, Jinming Gao b a Department of Biomedical Engineering, Case Western…

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Original Research In vivo angiogenesis imaging of solid tumors by avb3-targeted, dual-modality micellar nanoprobes Chase W Kessinger1, Chalermchai Khemtong1, Osamu Togao2, Masaya Takahashi2, Baran D Sumer3 and Jinming Gao1 1Department of Pharmacology, Harold C Simmons Comprehensive Cancer Center…