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ARTICLE Polycarbonate-based ultra-pH sensitive nanoparticles improve therapeutic window Xu Wang 1, Jonathan Wilhelm 1, Wei Li1, Suxin Li1, Zhaohui Wang1, Gang Huang1, Jian Wang1, Houliang Tang1, Sina Khorsandi 2, Zhichen Sun 1, Bret Evers 3 & Jinming Gao 1✉ Stimuli-sensitive nanomaterials with coo…

A STING-activating nanovaccine for cancer immunotherapy Min Luo1†, Hua Wang2†, Zhaohui Wang1†, Haocheng Cai2, Zhigang Lu3, Yang Li1, Mingjian Du2, Gang Huang1, Chensu Wang1, Xiang Chen2, Matthew R. Porembka4, Jayanthi Lea5, Arthur E. Frankel6, Yang-Xin Fu7, Zhijian J. Chen2,8* and Jinming Gao1* The …

http://www.tandfonline.com/idrt ISSN: 1061-186X (print), 1029-2330 (electronic) J Drug Target, 2015; 23(7–8): 672–680 ! 2015 Taylor & Francis. DOI: 10.3109/1061186X.2015.1073296 REVIEW ARTICLE Nanotechnology-enabled delivery of NQO1 bioactivatable drugs Xinpeng Ma*y, Zachary R. Moore*, Gang Huang…

Journal of Controlled Release 329 (2021) 353–360 Available online 7 December 2020 0168-3659/© 2020 Elsevier B.V. All rights reserved. Antigen folding improves loading efficiency and antitumor efficacy of PC7A nanoparticle vaccine Jonathan Wilhelm, Manuel Quiñones-Pérez, Jian Wang, Xu Wang, Vij…

NATURE BIOMEDICAL ENGINEERING 1, 0006 (2016) | DOI: 10.1038/s41551-016-0006 | www.nature.com/natbiomedeng 1 ARTICLES PUBLISHED: 19 DECEMBER 2016 | VOLUME: 1 | ARTICLE NUMBER: 0006 A transistor-like pH nanoprobe for tumour detection and image-guided surgery Tian Zhao1​†, Gang Huang1, Yang Li1, Shu…

β‑Lapachone and Paclitaxel Combination Micelles with Improved Drug Encapsulation and Therapeutic Synergy as Novel Nanotherapeutics for NQO1-Targeted Cancer Therapy Ling Zhang,† Zhen Chen,† Kuan Yang,† Chun Liu,† Jinming Gao,‡ and Feng Qian*,† †Department of Pharmacology and Pharmaceutical Sciences a…

Critical ReviewsTM in Eukaryotic Gene Expression, 24(1):15-28 (2014) 151045-4403/14/$35.00 © 2014 Begell House, Inc. www.begellhouse.com Review of Poly (ADP-ribose) Polymerase (PARP) Mechanisms of Action and Rationale for Targeting in Cancer and Other Diseases Julio C. Morales,1 Longshan Li,1 Far…

ARTICLE Received 23 May 2016 | Accepted 13 Sep 2016 | Published 27 Oct 2016 Molecular basis of cooperativity in pH-triggered supramolecular self-assembly Yang Li1, Tian Zhao1, Chensu Wang1,2, Zhiqiang Lin1, Gang Huang1, Baran D. Sumer3 & Jinming Gao1 Supramolecular self-assembly offers a powerful …

Micellization DOI: 10.1002/anie.201402525 Chaotropic-Anion-Induced Supramolecular Self-Assembly of Ionic Polymeric Micelles** Yang Li, Yiguang Wang, Gang Huang, Xinpeng Ma, Kejin Zhou, and Jinming Gao* Dedicated to Professor George M. Whitesides on the occasion of his 75th birthday Abstract: Tradi…

Ultra-pH-Sensitive Nanoprobe Library with Broad pH Tunability and Fluorescence Emissions Xinpeng Ma,†,‡ Yiguang Wang,†,‡ Tian Zhao,† Yang Li,† Lee-Chun Su,† Zhaohui Wang,† Gang Huang,† Baran D. Sumer,§ and Jinming Gao*,†,∥ †Department of Pharmacology and §Department of Otolaryngology, Simmons Compr…