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#!/usr/bin/perl   open(FILE,  "accepted_hits_sorted.sam")  or  die("Unable  to  open  file");   open(OUTPUT,  ">final-­‐alignment.sam")  or  die("Unable  to  open  file");     use  strict;   my  $i;   my  $line;   my  $line1;   my  @group;   my  …

#!/usr/bin/perl     open(FILE1,  "Input.fastq")  or  die("Unable  to  open  file");   open(OUTPUT,  ">Output.fastq")  or  die("Unable  to  open  file");   use  strict;     my  $line;   my  @line;   my  $line1;   my  $seq0;   my  $junk;   my …

\ PEGSITACIANINE FOR THE SURGICAL DETECTION OF HEAD AND NECK CANCER PURPOSE INCLUSION DESIGN To investigate whether Pegsitacianine a fluorescent nanoparticle can image head and neck cancer and unknown primary head and neck cancer during surgery or biopsy. 1. Adul…

Theranostics 2020, Vol. 10, Issue 7 http://www.thno.org 3340 Theranostics 2020; 10(7): 3340-3350. doi: 10.7150/thno.41239 Research Paper Detection of Lymph Node Metastases by Ultra-pH-Sensitive Polymeric Nanoparticles Zachary T. Bennett1, Qiang Feng1, Justin A. Bishop2, Gang Huang1, …

NATURE BIOMEDICAL ENGINEERING 1, 0006 (2016) | DOI: 10.1038/s41551-016-0006 | www.nature.com/natbiomedeng 1 ARTICLES PUBLISHED: 19 DECEMBER 2016 | VOLUME: 1 | ARTICLE NUMBER: 0006 A transistor-like pH nanoprobe for tumour detection and image-guided surgery Tian Zhao1​†, Gang Huang1, Yang Li1, Shu…

Cooperativity Principles in Self-Assembled Nanomedicine Yang Li,† Yiguang Wang,†,‡ Gang Huang,† and Jinming Gao*,† †Department of Pharmacology, Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390, United States ‡Beijing Key Laboratory …

ARTICLE Polycarbonate-based ultra-pH sensitive nanoparticles improve therapeutic window Xu Wang 1, Jonathan Wilhelm 1, Wei Li1, Suxin Li1, Zhaohui Wang1, Gang Huang1, Jian Wang1, Houliang Tang1, Sina Khorsandi 2, Zhichen Sun 1, Bret Evers 3 & Jinming Gao 1✉ Stimuli-sensitive nanomaterials with coo…

ARTICLES PUBLISHED ONLINE: 8 DECEMBER 2013 | DOI: 10.1038/NMAT3819 A nanoparticle-based strategy for the imaging of a broad range of tumours by nonlinear amplification of microenvironment signals Yiguang Wang1, Kejin Zhou1, Gang Huang1, Christopher Hensley2, Xiaonan Huang1, Xinpeng Ma1, Tian Zhao1, …

Nano-Immune-Engineering Approaches to Advance Cancer Immunotherapy: Lessons from Ultra-pH-Sensitive Nanoparticles Published as part of the Accounts of Chemical Research special issue “Chemistry in Cancer Immunotheranostics”. Suxin Li, Zachary T. Bennett, Baran D. Sumer, and Jinming Gao* Cite This: …

Articles https://doi.org/10.1038/s41551-020-00675-9 1Department of Pharmacology, Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, USA. 2Department of Pathology, Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern…