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Jan’s Lab is interested in understanding the dynamics of protein-RNA complexes during ribosome biogenesis. We are particularly focused on the roles of ATPases in coordinating ribosomal RNA processing and remodeling events, as well as the importance of these enzymes in signaling between the ribosome biogenesis pathway and the cell cycle machinery.

Skip to main content Publications Featured Publications Evaluating Therapeutic Efficacy of the Vascular Disrupting Agent OXi8007 Against Kidney Cancer in Mice. Wanniarachchi HI, Schuetze R, Deng Y, Hamal KB, Pavlich CI, Tankoano PEO, Tamminga C, Hammers H, Kapur P, Bueno LMA, Rayas R, Wang T, Liu L, …

My lab has a long-time interest in understanding the mechanisms of transcription and gene regulation in mammalian cells using initially cell-free systems reconstituted with purified gene-specific transcription factors, general cofactors, and components of the general transcription machinery to recapitulate transcriptional events in vitro. 

Our lab focuses on the molecular and cellular mechanisms underlying cell fate specification during blood vessel development and organogenesis.

Kitamura Lab's research aims to provide a biophysically-based mechanistic understanding of the neural process for learning and memory in the mouse brain.

Skip to main content Grants Dates Principal Investigator(s) Grant No./ Donor Title Goal 09/2025 – 08/2028 Li Liu, PhD 25-30-73-LIU, AACR Imaging-Guided Assessment of Synergistic Treatments for Breast Cancer Develop combination therapies with Cyclopamine Tartrate (CycT) that can normalize the tumor mi…

Skip to main content Research Dr. Liu’s research focuses on the development of reporter genes and the evaluation of reporter gene applications in preclinical cellular and molecular imaging, particularly in small animal models of breast, prostate, lung, and brain cancers, including subcutaneous, ortho…

Skip to main content Meet Our Collaborators Ralph P. Mason, Ph.D. Professor of Radiology Email Faculty Profile Research Interests Tumor Pathophysiology (Hypoxia; Blood Flow; pO2; pH, BOLD MRI); Multimodality Imaging: optical (BLI, FLI, CLI), PET, MRI; Reporter Molecules (pH, pO2, enzyme activity); 19…

Skip to main content Contact Us Questions or comments about the Predictive Imaging Research Laboratory may be addressed to: Li Liu, Ph.D. Associate Professor and Principal Investigator Email Department of Radiology Hoblitzelle Building (G) 2nd floor 5323 Harry Hines Blvd. Dallas, TX 75390-9058 Phone:…

Current opportunities in the Samir Parikh Research lab.