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Skip to main content Photo Gallery May 2024 - Katerina running our first peptide synthesis in the lab November 2024 - Bowling it out at Bowl & Barrel - Team (shamefully) losing twice! November 2024 - Laxmikant cleaning peps December 2024 - Vasilis running FIDA with some swagger! January 2025 - Celebr…

Skip to main content Publications for Xuewu Zhang, Ph.D. Regulation of STING activation by phosphoinositide and cholesterol. Li J, Tan JX, Chen ZJ, Zhang X, Bai XC, 2026 Feb Nature PtdIns(3,5)P2 is an endogenous ligand of STING in innate immune signalling. Tan JX, Lv B, Li J, Li T, Du F, Chen X, Zhan…

Skip to main content Research Advancing science through improvised solutions and emerging innovations to improve the delivery of medical care. Radiologically Isolated Syndrome (RIS) Dr. Okuda originally described the radiologically isolated syndrome in 2009, highlighting a group of individuals with i…

Skip to main content Lab Projects Research in the D'Orso Lab focuses on understanding molecular mechanisms of transcriptional regulation and defining how these normal programs become deregulated during viral infections and disease states. Another aspect is on the host-pathogen interaction between vir…

Skip to main content Gallery PlexinD1/GIPC/myosin VI: oligomerization for transportation A comprehensive structural analyses show how PlexinD1 binds the adaptor protein GIPC1, releasing the autoinhibition in GIPC1 and promoting its interaction with the motor protein myosin VI. Surprisingly, GIPC and …

Skip to main content Publications A Pre-symptomatic phase of tumefactive multiple sclerosis mirrors radiologically isolated syndrome Aboseif A, Neyal N, Keegan BM, Eckel-Passow JE, Siva A, Lebrun-Frenay C, Okuda DT, Tobin WO, Zeydan B, Kantarci OH 2026 Aug Multiple Sclerosis and Related Disorders 112…

Skip to main content Meet the Team Ying Xian, M.D., Ph.D. Principal Investigator & Associate Professor Dr. Xian earned his medical degree at Beijing Medical University (Peking University Health Science Center), completed a residency in Internal Medicine, and a fellowship in Cardiology at Peking Unive…

Skip to main content Research Reperfusion therapy in ischemic stroke Intravenous thrombolytic therapy and endovascular thrombectomy are the mainstay of treatment for patients with acute ischemic stroke. Although not evidence-based, treatment is often withheld due to safety concerns in patients with a…

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