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Purbita Saha, Ph.D. Candidate Genetics, Development, and Disease Graduate Program “A Variant in Balance: Fine-tuning of Histone H3.3 Occupancy by PHF11 Drives Chromatin Accessibility in Embryonic Stem Cells” Mentor: Laura Banaszynski, Ph.D., powered by Localist, the Community Event Platform

Sydni Shorter, Ph.D. Candidate Clinical Psychology Graduate Program “Exploring Diagnostic Accuracy of Autism Spectrum Disorder in Black and Latine Children” Mentors: Veronica Bordes Edgar, Ph.D., ABPP and Beatriz MacDonald Wer, Ph.D., powered by Localist, the Community Event Platform

Anesthesiology & Pain Management presents Faculty Bootcamp Elite Series: "Pathways to Success: A Junior Faculty Learning Series: Building Momentum-How to excel in your 4th year review?" Speaker: Anu Wadhwa, M.D. Professor, Department of Anesthesiology & Pain Management UT Southwestern Medical Center This activity has been approved for AMA PRA Category 1 CreditsTM Please contact Brian Frasure if you have questions or concerns, powered by Localist, the Community Event Platform

Ryan O'Hara, Ph.D. Candidate Genetics, Development, and Disease Graduate Program “Accessibility vs Restraint: Chromatin Control of Enhancers and Retrotransposons Shapes Cell State and Survival” Mentor: Laura Banaszynski, Ph.D., powered by Localist, the Community Event Platform

"Regulating when and where a microtubule assembles: put a gamma-tubulin ring on it" Speaker: Tarun Kapoor, Ph.D. Professor at Rockefeller University Abstract: Microtubules, polymers of alpha/beta-tubulin, provide tracks for intracellular transport. These cytoskeletal filaments are required for cell division, regulation of cell polarity and morphogenesis. Microtubules are also targets for therapeutic agents used to treat diseases such as cancer. The formation of cellular microtubule networks is regulated by the γ-tubulin ring complex (γ-TuRC), a large (∼2.3 MD) multiprotein assembly. This complex not only regulates where and when a microtubule is formed, but may also control filament architecture, polarity and anchoring. I will discuss our cryo-EM reconstructions of the γ-TuRC and describe how it is assembled by >31 proteins, including γ-tubulin and an actin-containing "lumenal bridge". These structural models have guided the biochemical reconstitution of the γ-TuRC with 10 proteins and allowed st…

"RNA Structure-Dependent miR Clustering Governs PKD1 Dosage and ADPKD Severity" Speaker: Mauricio Ostrosky-Frid, M.D., Ph.D. PSTP Fellow Division of Nephrology UT Southwestern Medical Center About Mauricio Ostrosky-Frid: Originally from Mexico, Dr. Ostrosky-Frid earned his medical degree and his doctorate from National Autonomous University of Mexico in Mexico City. He completed internal medicine residency training at UT Southwestern before beginning fellowship training in nephrology through the Physician Scientist Training Program (PSTP). He is currently training with Vishal Patel, M.D., and Ronak Lakhia, M.D., with a special interest in genetic kidney diseases, especially Autosomal Dominant Polycystic Kidney Disease (ADPDK), and the mechanisms for mRNA regulation., powered by Localist, the Community Event Platform

Vikram Khurana, M.D., Ph.D. Tracy T. Batchelor Endowed Chair in Neurology at Mass General Brigham Chief of the Movement Disorders Division at Brigham and Women's Hospital Associate Professor of Neurology at Harvard Medical School Title: "Alpha-Synuclein in mRNA Metabolism and Gene Regulation", powered by Localist, the Community Event Platform

Matthew Hutnyan, Ph.D. Candidate Clinical Psychology Graduate Program “Affective Cognition and Interpersonal Functioning Among Adults With and Without Depression” Mentor: Shawn M. McClintock, Ph.D., MSCS, powered by Localist, the Community Event Platform

The third annual UT Southwestern Pancreatic Cancer Symposium CME event offers clinicians an opportunity to stay abreast of the latest treatment approaches for pancreatic cancer. This one-day live event will include topics such as: Molecular profiling and targeted therapeuticsMinimally invasive and robotic surgical techniquesRedefining the role of radiation therapy for pancreatic cancerEmerging systemic therapy strategiesClinical trial opportunities for advanced disease and pancreatic neuroendocrine tumorsAll heath care professionals are welcome. This activity is approved for AMA PRA Category 1 Credit(s)™️, powered by Localist, the Community Event Platform

Get ready for an exciting and vibrant afternoon of fun, food, and festivities as we come together to celebrate Pride Month with the UT Southwestern community. Come out to enjoy music with a live DJ, fun giveaways, games, and complimentary lunch. All members of the UTSW community and their guests are welcome to attend so join us for opportunities to connect, engage, and show your pride at the campus celebration. Food and swag will be available on a first come, first served basis. The gates at the T. Boone Pickens Visitors Garage will also be open at the time of this event. Space is limited, so register early to secure your spot. The celebration is hosted by the Office for Institutional Opportunity and the Office for Student Empowerment and Engagement. Registration is closed., powered by Localist, the Community Event Platform