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Unannotated translation products are widespread in model E. coli Speaker: Scott Saunders, PhD UTSW Distinguished Fellow Lyda Hill Department of Bioinformatics Abstract: E. coli MG1655 has ~4,300 annotated protein coding genes, and many of these gene products have been studied intensely, leading to foundational advances in molecular and systems biology. Each gene is bounded by a start and stop codon, however, many other start and stop codons are found throughout the genome, forming hundreds of thousands of possible open reading frames (ORFs). Recent work has shown that some unannotated ORFs are translated into detectable polypeptides, but it remains unclear if there are significant numbers of functional protein coding genes left to be discovered in model E. coli. To address this question, we are using our oligo-based genetic method, ORBIT, to construct high throughput, highly targeted mutant libraries that can probe ORFs genome-wide for translation and fitness phenotypes. We first sought to precisel…

Anesthesiology & Pain Management presents Faculty Bootcamp Elite Series: "Leading towards your title: The Power of Influence and Impact" Speaker: Anu Wadhwa, M.D. Professor Department of Anesthesiology & Pain Management UT Southwestern Medical Center This activity has been approved for AMA PRA Category 1 CreditsTM Please contact Brian Frasure if you have questions or concerns, powered by Localist, the Community Event Platform

Integrating AlphaFold3 with Astrocyte for Advanced Biomolecular Research Speaker: Xin Yang, PhD Computational Scientist, BioHPC This informative event will focus on: • An overview of the Astrocyte platform • How to run AlphaFold3 on Astrocyte • Real-world examples to demonstrate its capabilities This session is ideal for researchers looking to integrate AlphaFold3 into their computational workflows and maximize the potential of BioHPC’s resources. For any questions or more information, please contact us at BioHPC-Help@UTSouthwestern.edu. BioHPC: Your HPC Partner at UT Southwestern BioHPC is your one-stop shop for high-performance computing at UT Southwestern. We're committed to providing the infrastructure, expertise, and collaborative environment you need to propel your biomedical research. Whether you're a PhD student, Postdoctoral researcher, or faculty member, we're here to help you harness the power of computation and achieve groundbreaking results. BioHPC provi…

Anesthesiology & Pain Management presents Grand Rounds: "The Intersection of Anesthesia and Neurodevelopment: Advancements in Research" Speaker: Dusica Bajic, M.D., PhD. Associate Professor Department of Anesthersiology, Critical Care and Pain Medicine Boston Children's Hospital, Boston, MA This activity has been approved for AMA PRA Category 1 CreditsTM Please contact Brian Frasure if you have questions or concerns, powered by Localist, the Community Event Platform

Building Your Financial Wellness Webinar Series Nearly a quarter of U.S. adults are in the "sandwich generation", caring for aging parents while supporting adult children. We’ll explore ways to navigate this challenging time without sacrificing your sanity or your retirement. You'll learn strategies to help you: • Prioritize your own financial needs and secure your retirement • Manage the costs of elder care and support adult children • Create a budget to navigate competing financial responsibilities • Evolve your plan over time as life changes Sponsored By: Benefits & Wellness Department, powered by Localist, the Community Event Platform

"Foto Test: Update" Speaker: Belinda Vicioso, M.D. Professor of Internal Medicine Division of Geriatric Medicine UT Southwestern Medical Center About Belinda Vicioso: Originally from New York City, Dr. Vicioso earned her bachelor’s degree from the Colegio Santo Domingo in the Dominican Republic. She received her medical degree with honors from Instituto Tecnologico de Santo Domingo, Dominican Republic, and completed internal medicine residency training at Hahnemann University Hospital in Philadelphia and St. Francis Medical Center in Trenton, New Jersey. She received advanced training through a fellowship in geriatric medicine at the University of Pennsylvania Medical School. She joined the UT Southwestern faculty in 1995. Prior to joining UT Southwestern, Dr. Vicioso served on the faculty at the University of Pennsylvania, the University of Medicine and Dentistry of New Jersey, the University of Maryland, and Seton Hall University. Dr. Vicioso’s academic interests include healt…

Building Your Financial Wellness Webinar Series Saving for a child's education is a crucial financial decision that can have a lasting impact on their future. In this webinar you’ll gain insights into how to make the best decisions for your situation. We’ll discuss: • Why saving for college matters • Common questions • Ways to save • How to avoid excessive debt when considering loans • Tips to get started Sponsored By: Benefits & Wellness Department, powered by Localist, the Community Event Platform

America Saves Week Series During this webinar you will learn: To navigate market fluctuations and keep a long-term perspective. Sponsored By: Benefits & Wellness Department, powered by Localist, the Community Event Platform

Please complete the registration form below. You are registering for the Biomedical Research Awareness Day (BRAD) event on Friday, April 18, 2025 from 12-1pm in South Campus D1.600, with a virtual option. Dr. Steven Gray, will deliver a keynote address. Lunch will be made available to those attending in-person. Please register here. Sponsored by the UT Southwestern CTSA Program, powered by Localist, the Community Event Platform

America Saves Week Series Hear from the experts about key drivers of the markets and economy that are impacting investors. We’ll share views on: • The state of the U.S. economy and key market drivers • Factors influencing market volatility • Investing in public markets Sponsored By: Benefits & Wellness Department, powered by Localist, the Community Event Platform