Secondary Faculty

Yuh Min Chook, Ph.D. • Lab Website •

Yuh Min Chook

The Chook Lab studies physical and cellular mechanisms of nuclear-cytoplasmic transport. We seek to understand molecular recognition in this system and to discover new classes of nuclear localization and export signals.

Diagram of cell membrane

Ryan Hibbs, Ph.D. • Lab Website •

Ryan Hibbs

Ryan’s lab studies the structural mechanisms underlying neurotransmitter receptor function. We are particularly interested in defining principles of allosteric activation and modulation, ion selectivity, and ligand recognition.

Diagram of cell receptor

W. Mike Henne, Ph.D. • Lab Website •

William Henne, Ph.D.

The Henne Lab studies how cellular membranes are sculpted during processes like vesicle budding, organelle biogenesis, and the formation of inter-organelle membrane contact sites. We employ both budding yeast and mammalian cellular systems to reveal molecular mechanisms of this membrane remodeling, and our main projects use combinations of cell biology, genetics, biochemistry, and structural biology to deeply understand cellular sculpting events.

Xin Liu, Ph.D. •

Xin Liu

The Liu Lab studies high-order chromatin organizations and their impacts on eukaryotic transcription in both normal and diseased states. We focus on understanding the molecular and biophysical bases of the interplay between transcriptional regulation and chromatin dynamics including chromatin loop and heterochromatin formation.

Diagram of chromatin formation

Yunsun Nam, Ph.D. • Lab Website •

Yunsun Nam

Our lab is interested in the biochemical and structural mechanisms in RNA-mediated gene regulation pathways important in development and cancer. We are currently focused on investigating how microRNAs are processed and regulated.

Diagram of microRNA function

Rama Ranganathan Ph.D. • Lab Website •

Rama Ragananatham

The Ranganathan Lab is interested in the design principles of biological systems, focusing on evolutionary principles of proteins and cellular signaling networks.

Protein ribbon diagrams

Kimberly Reynolds, Ph.D.  • Lab Website •

Rama Ragananatham
The Reynolds Lab uses statistical analysis, comparative genomics, and epistasis experiments to understand the architecture and evolution of cellular systems. We are particularly interested in the evolutionary constraints on central metabolism, and large cellular structures like the flagellum. 
Protein ribbon diagrams

Xuewu Zhang, Ph.D. • Lab Website •

Xuewu Zhang

We study how signals are transduced across the cell membrane by using crystallography in combination with other approaches, focusing on the axon guidance receptor plexin.

Diagram of cell membrane