Yuh Min Chook, Ph.D. • Lab Website • firstname.lastname@example.org
The Chook Lab studies physical and cellular mechanisms of nuclear-cytoplasmic transport. We seek to understand molecular recognition in this system and to discover new classes of nuclear localization and export signals.
W. Mike Henne, Ph.D. • Lab Website • email@example.com
The Henne Lab studies how cellular membranes are sculpted during processes like vesicle budding, organelle biogenesis, and the formation of inter-organelle membrane contact sites. We employ both budding yeast and mammalian cellular systems to reveal molecular mechanisms of this membrane remodeling, and our main projects use combinations of cell biology, genetics, biochemistry, and structural biology to deeply understand cellular sculpting events.
Ryan Hibbs, Ph.D. • Lab Website • firstname.lastname@example.org
Ryan’s lab studies the structural mechanisms underlying neurotransmitter receptor function. We are particularly interested in defining principles of allosteric activation and modulation, ion selectivity, and ligand recognition.
Youxing Jiang, Ph.D. • Lab Website • email@example.com
The overall research goal of the Jiang Lab is to understand the structure and function of tetrameric cation channels, utilizing a combination of membrane protein crystallography and channel electrophysiology.
Milo Lin, Ph.D. • Lab Website • firstname.lastname@example.org
Milo's lab uses statistical mechanical and computational approaches to find performance limits of complex biological systems. These include the multi-scale mechanisms of protein folding, dynamics and aggregation (especially in neuro-toxicity and cell plasticity).
Xin Liu, Ph.D. • Xin.Liu@utsouthwestern.edu
The Liu Lab studies high-order chromatin organizations and their impacts on eukaryotic transcription in both normal and diseased states. We focus on understanding the molecular and biophysical bases of the interplay between transcriptional regulation and chromatin dynamics including chromatin loop and heterochromatin formation.
Xuelian Luo, Ph.D. • Lab Website • email@example.com
The Luo laboratory studies the molecular mechanisms of intracellular signal transduction pathways using a combination of structural and biochemical approaches. Our research program currently focuses on two major areas: the spindle checkpoint and the Hippo tumor suppressor pathway.
Yunsun Nam, Ph.D. • Lab Website • firstname.lastname@example.org
Our lab is interested in the biochemical and structural mechanisms in RNA-mediated gene regulation pathways important in development and cancer. We are currently focused on investigating how microRNAs are processed and regulated.
Daniela Nicastro, Ph.D. • email@example.com
The Nicastro lab develops and uses modern electron microscopy and image processing techniques in combination with molecular genetics and biochemistry to study the structure and function of macromolecular machines and organelles. We are particularly interested in the molecular mechanisms of ciliary motility and DNA repair.
Rama Ranganathan Ph.D. • Lab Website • firstname.lastname@example.org
The Ranganathan Lab is interested in the design principles of biological systems, focusing on evolutionary principles of proteins and cellular signaling networks.
Kimberly Reynolds, Ph.D. • Lab Website • email@example.com
Xuewu Zhang, Ph.D. • Lab Website • firstname.lastname@example.org
We study how signals are transduced across the cell membrane by using crystallography in combination with other approaches, focusing on the axon guidance receptor plexin.