Publications

2014

Augustyn, A., Borromeo, M., Wang, T., Fujimoto, J., Shao, C., Dospoy, P.D., Lee, V., Tan, C., Sullivan, J.P., Larsen, J.E., Girard, L., Behrens, C., Wistuba, II, Xie, Y., Cobb, M.H., Gazdar, A.F., Johnson, J.E., Minna, J.D., ASCL1 is a lineage oncogene providing therapeutic targets for high-grade neuroendocrine lung cancers. Proc Natl Acad Sci U S A, 2014

Barone, A., Sengupta, R., Warrington, N.M., Smith, E., Wen, P.Y., Brekken, R.A., Romagnoli, B., Douglas, G., Chevalier, E., Bauer, M.P., Dembowsky, K., Piwnica-Worms, D., Rubin, J.B., Combined VEGF and CXCR4 antagonism targets the GBM stem cell population and synergistically improves survival in an intracranial mouse model of glioblastoma. Oncotarget, 2014

Tran, T.A., Wichterman-Kouznetsova, J., Varghese, D., Huang, R., Huang, W., Becker, M., Austin, C.P., Inglese, J., Johnson, R.L., Martinez, E.D., Identification of Small Molecule Modulators of Gene Transcription with Anticancer Activity. ACS Chem Biol, 2014

Kim, J., Hsia, E.Y., Kim, J., Sever, N., Beachy, P.A., Zheng, X., Simultaneous measurement of smoothened entry into and exit from the primary cilium. PLoS One, 9: e104070, 2014

Ostapoff, K.T., Cenik, B.K., Wang, M., Ye, R., Xu, X., Nugent, D., Hagopian, M.M., Topalovski, M., Rivera, L.B., Carroll, K.D., Brekken, R.A., Neutralizing Murine TGFbetaR2 Promotes a Differentiated Tumor Cell Phenotype and Inhibits Pancreatic Cancer Metastasis. Cancer Res, 74: 4996-5007, 2014

Taguchi, A., Taylor, A.D., Rodriguez, J., Celiktas, M., Liu, H., Ma, X., Zhang, Q., Wong, C.H., Chin, A., Girard, L., Behrens, C., Lam, W.L., Lam, S., Minna, J.D., Wistuba, II, Gazdar, A.F., Hanash, S.M., A Search for Novel Cancer/Testis Antigens in Lung Cancer Identifies VCX/Y Genes, Expanding the Repertoire of Potential Immunotherapeutic Targets. Cancer Res, 74: 4694-705, 2014

Mathur, A., Ware, C., Davis, L., Gazdar, A., Pan, B.S., Lutterbach, B., FGFR2 Is Amplified in the NCI-H716 Colorectal Cancer Cell Line and Is Required for Growth and Survival. PLoS One, 9: e98515, 2014

Shao, C., Sullivan, J.P., Girard, L., Augustyn, A., Yenerall, P., Rodriguez-Canales, J., Liu, H., Behrens, C., Shay, J.W., Wistuba, II, Minna, J.D., Essential role of aldehyde dehydrogenase 1A3 for the maintenance of non-small cell lung cancer stem cells is associated with the STAT3 pathway. Clin Cancer Res, 20: 4154-66, 2014

Leroy, B., Girard, L., Hollestelle, A., Minna, J.D., Gazdar, A.F., Soussi, T., Analysis of TP53 mutation status in human cancer cell lines: a reassessment. Hum Mutat, 35: 756-65, 2014 

Hubers, A.J., van der Drift, M.A., Prinsen, C.F., Witte, B.I., Wang, Y., Shivapurkar, N., Stastny, V., Bolijn, A.S., Hol, B.E., Feng, Z., Dekhuijzen, P.N., Gazdar, A.F., Thunnissen, E., Methylation analysis in spontaneous sputum for lung cancer diagnosis. Lung Cancer, 84: 127-33, 2014

Dellinger, M.T., Garg, N., Olsen, B.R., Viewpoints on vessels and vanishing bones in Gorham-Stout disease. Bone, 63: 47-52, 2014

Yang, L., Kwon, J., Popov, Y., Gajdos, G.B., Ordog, T., Brekken, R.A., Mukhopadhyay, D., Schuppan, D., Bi, Y., Simonetto, D., Shah, V.H., Vascular endothelial growth factor promotes fibrosis resolution and repair in mice. Gastroenterology, 146: 1339-50 e1, 2014 

Kim, D.J., Kim, J., Spaunhurst, K., Montoya, J., Khodosh, R., Chandra, K., Fu, T., Gilliam, A., Molgo, M., Beachy, P.A., Tang, J.Y., Open-label, exploratory phase II trial of oral itraconazole for the treatment of basal cell carcinoma. J Clin Oncol, 32: 745-51, 2014

Delgado, O., Batten, K.G., Richardson, J.A., Xie, X.J., Gazdar, A.F., Kaisani, A.A., Girard, L., Behrens, C., Suraokar, M., Fasciani, G., Wright, W.E., Story, M.D., Wistuba, II, Minna, J.D., Shay, J.W., Radiation-enhanced lung cancer progression in a transgenic mouse model of lung cancer is predictive of outcomes in human lung and breast cancer. Clin Cancer Res, 20: 1610-22, 2014 

D'Amico, G., Korhonen, E.A., Anisimov, A., Zarkada, G., Holopainen, T., Hagerling, R., Kiefer, F., Eklund, L., Sormunen, R., Elamaa, H., Brekken, R.A., Adams, R.H., Koh, G.Y., Saharinen, P., Alitalo, K., Tie1 deletion inhibits tumor growth and improves angiopoietin antagonist therapy. J Clin Invest, 124: 824-34, 2014

Gazdar, A.F., EGFR Mutations in Lung Cancer: Different Frequencies for Different Folks. J Thorac Oncol, 9: 139-40, 2014

Brekken, R.A., Faulty ECM signaling facilitates autoimmune lymphomagenesis. Cancer Discov, 4: 25-6, 2014 

Song, S.Y., Das, A.K., Minna, J.D., Comparison between concurrent and sequential chemoradiation for non-small cell lung cancer. Oncol Lett, 7: 307-310, 2014

Aguilera, K.Y., Rivera, L.B., Hur, H., Carbon, J.G., Toombs, J.E., Goldstein, C.D., Dellinger, M.T., Castrillon, D.H., Brekken, R.A., Collagen signaling enhances tumor progression after anti-VEGF therapy in a murine model of pancreatic ductal adenocarcinoma. Cancer Res, 74: 1032-44, 2014 

Wilson, I.M., Vucic, E.A., Enfield, K.S., Thu, K.L., Zhang, Y.A., Chari, R., Lockwood, W.W., Radulovich, N., Starczynowski, D.T., Banath, J.P., Zhang, M., Pusic, A., Fuller, M., Lonergan, K.M., Rowbotham, D., Yee, J., English, J.C., Buys, T.P., Selamat, S.A., Laird-Offringa, I.A., Liu, P., Anderson, M., You, M., Tsao, M.S., Brown, C.J., Bennewith, K.L., MacAulay, C.E., Karsan, A., Gazdar, A.F., Lam, S., Lam, W.L., EYA4 is inactivated biallelically at a high frequency in sporadic lung cancer and is associated with familial lung cancer risk. Oncogene, 33: 4464-73, 2014

Ribeiro, N., Sousa, S.R., Brekken, R.A., Monteiro, F.J., Role of SPARC in bone remodeling and cancer-related bone metastasis. J Cell Biochem, 115: 17-26, 2014

Aguilera, K.Y., Brekken, R.A., Recruitment and retention: factors that affect pericyte migration. Cell Mol Life Sci, 71: 299-309, 2014

Gazdar, A., Zhou, C., Lung cancer in never smokers: A different disease, in The IASLC multidisciplinary approach to thoracic oncology, H. Pass, D. Ball, and G. Scagliotti, Editors. 2014, IASLC Press: Auroraa, CO. p. 35-44.

Gazdar, A., Robinson, L., Oliver, D., Xing, C., Travis, W., Soh, J., Toyooka, S., Watumull, L., Xie, Y., Kernstine, K., Schiller, J., Hereditary lung cancer syndrome targets never smokers with germline EGFR gene T790M mutations. J Thor Oncol, 9: 456-463, 2014

2013

Kim, H.S., Mendiratta, S., Kim, J., Pecot, C.V., Larsen, J.E., Zubovych, I., Seo, B.Y., Kim, J., Eskiocak, B., Chung, H., McMillan, E., Wu, S., De Brabander, J., Komurov, K., Toombs, J.E., Wei, S., Peyton, M., Williams, N., Gazdar, A.F., Posner, B.A., Brekken, R.A., Sood, A.K., Deberardinis, R.J., Roth, M.G., Minna, J.D., White, M.A., Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer. Cell, 155: 552-66, 2013

Zaganjor, E., Osborne, J.K., Weil, L.M., Diaz-Martinez, L.A., Gonzales, J.X., Singel, S.M., Larsen, J.E., Girard, L., Minna, J.D., Cobb, M.H., Ras regulates kinesin 13 family members to control cell migration pathways in transformed human bronchial epithelial cells. Oncogene, 2013

Wu, Q., Ishikawa, T., Sirianni, R., Tang, H., McDonald, J.G., Yuhanna, I.S., Thompson, B., Girard, L., Mineo, C., Brekken, R.A., Umetani, M., Euhus, D.M., Xie, Y., Shaul, P.W., 27-Hydroxycholesterol promotes cell-autonomous, ER-positive breast cancer growth. Cell Rep, 5: 637-45, 2013

Pikor, L.A., Lockwood, W.W., Thu, K.L., Vucic, E.A., Chari, R., Gazdar, A.F., Lam, S., Lam, W.L., YEATS4 is a novel oncogene amplified in non-small cell lung cancer that regulates the p53 pathway. Cancer Res, 73: 7301-12, 2013

Cooper, W.A., Lam, D.C., O'Toole, S.A., Minna, J.D., Molecular biology of lung cancer. J Thorac Dis, 5: S479-S490, 2013 

Davidson, M.R., Gazdar, A.F., Clarke, B.E., The pivotal role of pathology in the management of lung cancer. J Thorac Dis, 5: S463-S478, 2013

Meng, J., Majidi, M., Fang, B., Ji, L., Bekele, B.N., Minna, J.D., Roth, J.A., The Tumor Suppressor Gene TUSC2 (FUS1) Sensitizes NSCLC to the AKT Inhibitor MK2206 in LKB1-dependent Manner. PLoS One, 8: e77067, 2013

Bu, D., Lewis, C.M., Sarode, V., Chen, M., Ma, X., Lazorwitz, A.M., Rao, R., Leitch, M., Moldrem, A., Andrews, V., Gazdar, A.F., Euhus, D.M., Identification of Breast Cancer DNA Methylation Markers Optimized for Fine Needle Aspiration Samples. Cancer Epidemiol Biomarkers Prev, 2013 

Tam, K.W., Zhang, W., Soh, J., Stastny, V., Chen, M., Sun, H., Thu, K., Rios, J.J., Yang, C., Marconett, C.N., Selamat, S.A., Laird-Offringa, I.A., Taguchi, A., Hanash, S., Shames, D., Ma, X., Zhang, M.Q., Lam, W.L., Gazdar, A., CDKN2A/p16 Inactivation Mechanisms and Their Relationship to Smoke Exposure and Molecular Features in Non-Small-Cell Lung Cancer. J Thorac Oncol, 8: 1378-88, 2013 

Huffman, K., Martinez, E.D., Pre-Clinical Studies of Epigenetic Therapies Targeting Histone Modifiers in Lung Cancer. Front Oncol, 3: 235, 2013

Du, L., Zhao, Z., Ma, X., Hsiao, T.H., Chen, Y., Young, E., Suraokar, M., Wistuba, I., Minna, J.D., Pertsemlidis, A., miR-93-directed downregulation of DAB2 defines a novel oncogenic pathway in lung cancer. Oncogene, 2013

Wei, Y., Zou, Z., Becker, N., Anderson, M., Sumpter, R., Xiao, G., Kinch, L., Koduru, P., Christudass, C.S., Veltri, R.W., Grishin, N.V., Peyton, M., Minna, J., Bhagat, G., Levine, B., EGFR-mediated Beclin 1 phosphorylation in autophagy suppression, tumor progression, and tumor chemoresistance. Cell, 154: 1269-84, 2013

Dellinger, M.T., Meadows, S.M., Wynne, K., Cleaver, O., Brekken, R.A., Vascular endothelial growth factor receptor-2 promotes the development of the lymphatic vasculature. PLoS One, 8: e74686, 2013

Coe, B.P., Thu, K.L., Aviel-Ronen, S., Vucic, E.A., Gazdar, A.F., Lam, S., Tsao, M.S., Lam, W.L., Genomic Deregulation of the E2F/Rb Pathway Leads to Activation of the Oncogene EZH2 in Small Cell Lung Cancer. PLoS One, 8: e71670, 2013 

Gazdar, A.F., Minna, J.D., Precision medicine for cancer patients: lessons learned and the path forward. J Natl Cancer Inst, 105: 1262-3, 2013

Osborne, J.K., Larsen, J.E., Gonzales, J.X., Shames, D.S., Sato, M., Wistuba, II, Girard, L., Minna, J.D., Cobb, M.H., NeuroD1 regulation of migration accompanies the differential sensitivity of neuroendocrine carcinomas to TrkB inhibition. Oncogenesis, 2: e63, 2013

Myers, B.R., Sever, N., Chong, Y.C., Kim, J., Belani, J.D., Rychnovsky, S., Bazan, J.F., Beachy, P.A., Hedgehog pathway modulation by multiple lipid binding sites on the smoothened effector of signal response. Developmental Cell, 26: 346-57, 2013 

Villalta, S.A., Lang, J., Kubeck, S., Kabre, B., Szot, G.L., Calderon, B., Wasserfall, C., Atkinson, M.A., Brekken, R.A., Pullen, N., Arch, R.H., Bluestone, J.A., Inhibition of VEGFR-2 reverses type 1 diabetes in NOD mice by abrogating insulitis and restoring islet function. Diabetes, 62: 2870-8, 2013

Dai, B., Yoo, S.Y., Bartholomeusz, G., Graham, R.A., Majidi, M., Yan, S., Meng, J., Ji, L., Coombes, K., Minna, J.D., Fang, B., Roth, J.A., KEAP1-dependent synthetic lethality induced by AKT and TXNRD1 inhibitors in lung cancer. Cancer Res, 73: 5532-43, 2013 

Wang, L., Chang, J., Varghese, D., Dellinger, M., Kumar, S., Best, A.M., Ruiz, J., Bruick, R., Pena-Llopis, S., Xu, J., Babinski, D.J., Frantz, D.E., Brekken, R.A., Quinn, A.M., Simeonov, A., Easmon, J., Martinez, E.D., A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth. Nat Commun, 4: 2035, 2013

Ghayee, H.K., Bhagwandin, V.J., Stastny, V., Click, A., Ding, L.H., Mizrachi, D., Zou, Y.S., Chari, R., Lam, W.L., Bachoo, R.M., Smith, A.L., Story, M.D., Sidhu, S., Robinson, B.G., Nwariaku, F.E., Gazdar, A.F., Auchus, R.J., Shay, J.W., Progenitor Cell Line (hPheo1) Derived from a Human Pheochromocytoma Tumor. PLoS One, 8: e65624, 2013 

Ma, X., Wang, Y.W., Zhang, M.Q., Gazdar, A.F., DNA methylation data analysis and its application to cancer research. Epigenomics, 5: 301-16, 2013

Bennett, K.M., Afanador, M.D., Lal, C.V., Xu, H., Persad, E., Legan, S.K., Chenaux, G., Dellinger, M., Savani, R.C., Dravis, C., Henkemeyer, M., Schwarz, M.A., Ephrin-B2 reverse signaling increases alpha5beta1 integrin-mediated fibronectin deposition and reduces distal lung compliance. Am J Respir Cell Mol Biol, 49: 680-7, 2013

Kutluk Cenik, B., Ostapoff, K.T., Gerber, D.E., Brekken, R.A., BIBF 1120 (nintedanib), a triple angiokinase inhibitor, induces hypoxia but not EMT and blocks progression of preclinical models of lung and pancreatic cancer. Mol Cancer Ther, 12: 992-1001, 2013

Ding, L.H., Park, S., Peyton, M., Girard, L., Xie, Y., Minna, J.D., Story, M.D., Distinct transcriptome profiles identified in normal human bronchial epithelial cells after exposure to gamma-rays and different elemental particles of high Z and energy. BMC Genomics, 14: 372, 2013 

Hooda, J., Cadinu, D., Alam, M.M., Shah, A., Cao, T.M., Sullivan, L.A., Brekken, R., Zhang, L., Enhanced heme function and mitochondrial respiration promote the progression of lung cancer cells. PLoS One, 8: e63402, 2013

Ostapoff, K.T., Awasthi, N., Cenik, B.K., Hinz, S., Dredge, K., Schwarz, R.E., Brekken, R.A., PG545, an angiogenesis and heparanase inhibitor, reduces primary tumor growth and metastasis in experimental pancreatic cancer. Mol Cancer Ther, 12: 1190-201, 2013 

Osborne, J.K., Larsen, J.E., Shields, M.D., Gonzales, J.X., Shames, D.S., Sato, M., Kulkarni, A., Wistuba, II, Girard, L., Minna, J.D., Cobb, M.H., NeuroD1 regulates survival and migration of neuroendocrine lung carcinomas via signaling molecules TrkB and NCAM. Proc Natl Acad Sci U S A, 110: 6524-9, 2013

Shien, K., Toyooka, S., Yamamoto, H., Soh, J., Jida, M., Thu, K.L., Hashida, S., Maki, Y., Ichihara, E., Asano, H., Tsukuda, K., Takigawa, N., Kiura, K., Gazdar, A.F., Lam, W.L., Miyoshi, S., Acquired resistance to EGFR inhibitors is associated with a manifestation of stem cell-like properties in cancer cells. Cancer Res, 73: 3051-61, 2013 

Currier, M.A., Eshun, F.K., Sholl, A., Chernoguz, A., Crawford, K., Divanovic, S., Boon, L., Goins, W.F., Frischer, J.S., Collins, M.H., Leddon, J.L., Baird, W.H., Haseley, A., Streby, K.A., Wang, P.Y., Hendrickson, B.W., Brekken, R.A., Kaur, B., Hildeman, D., Cripe, T.P., VEGF blockade enables oncolytic cancer virotherapy in part by modulating intratumoral myeloid cells. Mol Ther, 21: 1014-23, 2013

Chatterjee, S., Heukamp, L.C., Siobal, M., Schottle, J., Wieczorek, C., Peifer, M., Frasca, D., Koker, M., Konig, K., Meder, L., Rauh, D., Buettner, R., Wolf, J., Brekken, R.A., Neumaier, B., Christofori, G., Thomas, R.K., Ullrich, R.T., Tumor VEGF:VEGFR2 autocrine feed-forward loop triggers angiogenesis in lung cancer. J Clin Invest, 123: 1732-40, 2013 

Sato, M., Larsen, J.E., Lee, W., Sun, H., Shames, D.S., Dalvi, M.P., Ramirez, R.D., Tang, H., Dimaio, J.M., Gao, B., Xie, Y., Wistuba, II, Gazdar, A.F., Shay, J.W., Minna, J.D., Human Lung Epithelial Cells Progressed to Malignancy through Specific Oncogenic Manipulations. Mol Cancer Res, 11: 638-50, 2013 

Kim, H.S., Minna, J.D., White, M.A., GWAS meets TCGA to illuminate mechanisms of cancer predisposition. Cell, 152: 387-9, 2013

Konstantinidou, G., Ramadori, G., Torti, F., Kangasniemi, K., Ramirez, R.E., Cai, Y., Behrens, C., Dellinger, M.T., Brekken, R.A., Wistuba, II, Heguy, A., Teruya-Feldstein, J., Scaglioni, P.P., RHOA-FAK is a required signaling axis for the maintenance of KRAS-driven lung adenocarcinomas. Cancer Discov, 3: 444-57, 2013 

Tang, H., Xiao, G., Behrens, C., Schiller, J., Allen, J., Chow, C.W., Suraokar, M., Corvalan, A., Mao, J., White, M.A., Wistuba, II, Minna, J.D., Xie, Y., A 12-gene set predicts survival benefits from adjuvant chemotherapy in non-small cell lung cancer patients. Clin Cancer Res, 19: 1577-86, 2013 

Said, N., Frierson, H.F., Sanchez-Carbayo, M., Brekken, R.A., Theodorescu, D., Loss of SPARC in bladder cancer enhances carcinogenesis and progression. J Clin Invest, 123: 751-66, 2013

Kim, J., Aftab, B.T., Tang, J.Y., Kim, D., Lee, A.H., Rezaee, M., Kim, J., Chen, B., King, E.M., Borodovsky, A., Riggins, G.J., Epstein, E.H., Jr., Beachy, P.A., Rudin, C.M., Itraconazole and arsenic trioxide inhibit Hedgehog pathway activation and tumor growth associated with acquired resistance to smoothened antagonists. Cancer Cell, 23: 23-34, 2013 

Li, X., Zhou, Q., Hanus, J., Anderson, C., Zhang, H., Dellinger, M., Brekken, R., Wang, S., Inhibition of multiple pathogenic pathways by histone deacetylase inhibitor SAHA in a corneal alkali-burn injury model. Mol Pharm, 10: 307-18, 2013 

Byers, L.A., Diao, L., Wang, J., Saintigny, P., Girard, L., Peyton, M., Shen, L., Fan, Y., Giri, U., Tumula, P.K., Nilsson, M.B., Gudikote, J., Tran, H., Cardnell, R.J., Bearss, D.J., Warner, S.L., Foulks, J.M., Kanner, S.B., Gandhi, V., Krett, N., Rosen, S.T., Kim, E.S., Herbst, R.S., Blumenschein, G.R., Lee, J.J., Lippman, S.M., Ang, K.K., Mills, G.B., Hong, W.K., Weinstein, J.N., Wistuba, II, Coombes, K.R., Minna, J.D., Heymach, J.V., An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance. Clin Cancer Res, 19: 279-90, 2013 

Travis, W.D., Brambilla, E., Noguchi, M., Nicholson, A.G., Geisinger, K., Yatabe, Y., Ishikawa, Y., Wistuba, I., Flieder, D.B., Franklin, W., Gazdar, A., Hasleton, P.S., Henderson, D.W., Kerr, K.M., Petersen, I., Roggli, V., Thunnissen, E., Tsao, M., Diagnosis of lung cancer in small biopsies and cytology: implications of the 2011 International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society classification. Arch Pathol Lab Med, 137: 668-84, 2013

Dasgupta, S., Jang, J.S., Shao, C., Mukhopadhyay, N.D., Sokhi, U.K., Das, S.K., Brait, M., Talbot, C., Yung, R.C., Begum, S., Westra, W.H., Hoque, M.O., Yang, P., Yi, J.E., Lam, S., Gazdar, A.F., Fisher, P.B., Jen, J., Sidransky, D., SH3GL2 is frequently deleted in non-small cell lung cancer and downregulates tumor growth by modulating EGFR signaling. J Mol Med (Berl), 91: 381-93, 2013 

Sunaga, N., Kaira, K., Imai, H., Shimizu, K., Nakano, T., Shames, D.S., Girard, L., Soh, J., Sato, M., Iwasaki, Y., Ishizuka, T., Gazdar, A.F., Minna, J.D., Mori, M., Oncogenic KRAS-induced epiregulin overexpression contributes to aggressive phenotype and is a promising therapeutic target in non-small-cell lung cancer. Oncogene, 32: 4034-42, 2013 

Travis, W.D., Brambilla, E., Noguchi, M., Nicholson, A.G., Geisinger, K., Yatabe, Y., Ishikawa, Y., Wistuba, I., Flieder, D.B., Franklin, W., Gazdar, A., Hasleton, P.S., Henderson, D.W., Kerr, K.M., Nakatani, Y., Petersen, I., Roggli, V., Thunnissen, E., Tsao, M., Diagnosis of lung adenocarcinoma in resected specimens: implications of the 2011 International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society classification. Arch Pathol Lab Med, 137: 685-705, 2013

Wilson, I.M., Vucic, E.A., Enfield, K.S., Thu, K.L., Zhang, Y.A., Chari, R., Lockwood, W.W., Radulovich, N., Starczynowski, D.T., Banath, J.P., Zhang, M., Pusic, A., Fuller, M., Lonergan, K.M., Rowbotham, D., Yee, J., English, J.C., Buys, T.P., Selamat, S.A., Laird-Offringa, I.A., Liu, P., Anderson, M., You, M., Tsao, M.S., Brown, C.J., Bennewith, K.L., Macaulay, C.E., Karsan, A., Gazdar, A.F., Lam, S., Lam, W.L., EYA4 is inactivated biallelically at a high frequency in sporadic lung cancer and is associated with familial lung cancer risk. Oncogene, 2013

Huffman, K., Martinez, E.D., Pre-clinical studies of epigenetic therapies targeting histone modifiers in lung cancer. Front Oncol, 3: 235, 2013

Ribeiro, N., Sousa, S.R., Brekken, R.A., Monteiro, F.J., Role of SPARC in bone remodeling and cancer-related bone metastasis. J Cell Biochem, 2013

Dellinger, M.T., Meadows, S.M., Wynne, K., Cleaver, O., Brekken, R.A., Vascular endothelial growth factor receptor-2 promotes the development of the lymphatic vasculature. PLoS One, 8: e74686, 2013

Coe, B.P., Thu, K.L., Aviel-Ronen, S., Vucic, E.A., Gazdar, A.F., Lam, S., Tsao, M.S., Lam, W.L., Genomic deregulation of the E2F/Rb pathway leads to activation of the oncogene EZH2 in small cell lung cancer. PLoS One, 8: e71670, 2013

Gazdar, A.F., Minna, J.D., Precision medicine for cancer patients: lessons learned and the path forward. J Natl Cancer Inst, 105: 1262-3, 2013

Osborne, J.K., Larsen, J.E., Gonzales, J.X., Shames, D.S., Sato, M., Wistuba, II, Girard, L., Minna, J.D., Cobb, M.H., NeuroD1 regulation of migration accompanies the differential sensitivity of neuroendocrine carcinomas to TrkB inhibition. Oncogenesis, 2: e63, 2013

Myers, B.R., Sever, N., Chong, Y.C., Kim, J., Belani, J.D., Rychnovsky, S., Bazan, J.F., Beachy, P.A., Hedgehog pathway modulation by multiple lipid binding sites on the smoothened effector of signal response. Dev Cell, 26: 346-57, 2013

Aguilera, K.Y., Brekken, R.A., Recruitment and retention: factors that affect pericyte migration. Cell Mol Life Sci, 2013

Villalta, S.A., Lang, J., Kubeck, S., Kabre, B., Szot, G.L., Calderon, B., Wasserfall, C., Atkinson, M.A., Brekken, R.A., Pullen, N., Arch, R.H., Bluestone, J.A., Inhibition of VEGFR-2 reverses type 1 diabetes in NOD mice by abrogating insulitis and restoring islet function. Diabetes, 62: 2870-8, 2013

Wang, L., Chang, J., Varghese, D., Dellinger, M., Kumar, S., Best, A.M., Ruiz, J., Bruick, R., Pena-Llopis, S., Xu, J., Babinski, D.J., Frantz, D.E., Brekken, R.A., Quinn, A.M., Simeonov, A., Easmon, J., Martinez, E.D., A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth. Nat Commun, 4: 2035, 2013

Ghayee, H.K., Bhagwandin, V.J., Stastny, V., Click, A., Ding, L.H., Mizrachi, D., Zou, Y.S., Chari, R., Lam, W.L., Bachoo, R.M., Smith, A.L., Story, M.D., Sidhu, S., Robinson, B.G., Nwariaku, F.E., Gazdar, A.F., Auchus, R.J., Shay, J.W., Progenitor cell line (hPheo1) derived from a human pheochromocytoma tumor. PLoS One, 8: e65624, 2013

Ma, X., Wang, Y.W., Zhang, M.Q., Gazdar, A.F., DNA methylation data analysis and its application to cancer research. Epigenomics, 5: 301-16, 2013

Kutluk Cenik, B., Ostapoff, K.T., Gerber, D.E., Brekken, R.A., BIBF 1120 (nintedanib), a triple angiokinase inhibitor, induces hypoxia but not EMT and blocks progression of preclinical models of lung and pancreatic cancer. Mol Cancer Ther, 12: 992-1001, 2013

Ding, L.H., Park, S., Peyton, M., Girard, L., Xie, Y., Minna, J.D., Story, M.D., Distinct transcriptome profiles identified in normal human bronchial epithelial cells after exposure to gamma-rays and different elemental particles of high Z and energy. BMC Genomics, 14: 372, 2013

Hooda, J., Cadinu, D., Alam, M.M., Shah, A., Cao, T.M., Sullivan, L.A., Brekken, R., Zhang, L., Enhanced heme function and mitochondrial respiration promote the progression of lung cancer cells. PLoS One, 8: e63402, 2013

Ostapoff, K.T., Awasthi, N., Cenik, B.K., Hinz, S., Dredge, K., Schwarz, R.E., Brekken, R.A., PG545, an angiogenesis and heparanase inhibitor, reduces primary tumor growth and metastasis in experimental pancreatic cancer. Mol Cancer Ther, 12: 1190-201, 2013

Osborne, J.K., Larsen, J.E., Shields, M.D., Gonzales, J.X., Shames, D.S., Sato, M., Kulkarni, A., Wistuba, II, Girard, L., Minna, J.D., Cobb, M.H., NeuroD1 regulates survival and migration of neuroendocrine lung carcinomas via signaling molecules TrkB and NCAM. Proc Natl Acad Sci U S A, 110: 6524-9, 2013

Shien, K., Toyooka, S., Yamamoto, H., Soh, J., Jida, M., Thu, K.L., Hashida, S., Maki, Y., Ichihara, E., Asano, H., Tsukuda, K., Takigawa, N., Kiura, K., Gazdar, A.F., Lam, W.L., Miyoshi, S., Acquired resistance to EGFR inhibitors is associated with a manifestation of stem cell-like properties in cancer cells. Cancer Res, 73: 3051-61, 2013

Currier, M.A., Eshun, F.K., Sholl, A., Chernoguz, A., Crawford, K., Divanovic, S., Boon, L., Goins, W.F., Frischer, J.S., Collins, M.H., Leddon, J.L., Baird, W.H., Haseley, A., Streby, K.A., Wang, P.Y., Hendrickson, B.W., Brekken, R.A., Kaur, B., Hildeman, D., Cripe, T.P., VEGF blockade enables oncolytic cancer virotherapy in part by modulating intratumoral myeloid cells. Mol Ther, 21: 1014-23, 2013

Chatterjee, S., Heukamp, L.C., Siobal, M., Schottle, J., Wieczorek, C., Peifer, M., Frasca, D., Koker, M., Konig, K., Meder, L., Rauh, D., Buettner, R., Wolf, J., Brekken, R.A., Neumaier, B., Christofori, G., Thomas, R.K., Ullrich, R.T., Tumor VEGF:VEGFR2 autocrine feed-forward loop triggers angiogenesis in lung cancer. J Clin Invest, 123: 1732-40, 2013

Sato, M., Larsen, J.E., Lee, W., Sun, H., Shames, D.S., Dalvi, M.P., Ramirez, R.D., Tang, H., Dimaio, J.M., Gao, B., Xie, Y., Wistuba, II, Gazdar, A.F., Shay, J.W., Minna, J.D., Human lung epithelial cells progressed to malignancy through specific oncogenic manipulations. Mol Cancer Res, 11: 638-50, 2013

Kim, H.S., Minna, J.D., White, M.A., GWAS meets TCGA to illuminate mechanisms of cancer predisposition. Cell, 152: 387-9, 2013

Konstantinidou, G., Ramadori, G., Torti, F., Kangasniemi, K., Ramirez, R.E., Cai, Y., Behrens, C., Dellinger, M.T., Brekken, R.A., Wistuba, II, Heguy, A., Teruya-Feldstein, J., Scaglioni, P.P., RHOA-FAK is a required signaling axis for the maintenance of KRAS-driven lung adenocarcinomas. Cancer Discov, 3: 444-57, 2013

Tang, H., Xiao, G., Behrens, C., Schiller, J., Allen, J., Chow, C.W., Suraokar, M., Corvalan, A., Mao, J., White, M.A., Wistuba, II, Minna, J.D., Xie, Y., A 12-gene set predicts survival benefits from adjuvant chemotherapy in non-small cell lung cancer patients. Clin Cancer Res, 19: 1577-86, 2013

Said, N., Frierson, H.F., Sanchez-Carbayo, M., Brekken, R.A., Theodorescu, D., Loss of SPARC in bladder cancer enhances carcinogenesis and progression. J Clin Invest, 123: 751-66, 2013

Kim, J., Aftab, B.T., Tang, J.Y., Kim, D., Lee, A.H., Rezaee, M., Kim, J., Chen, B., King, E.M., Borodovsky, A., Riggins, G.J., Epstein, E.H., Jr., Beachy, P.A., Rudin, C.M., Itraconazole and arsenic trioxide inhibit Hedgehog pathway activation and tumor growth associated with acquired resistance to smoothened antagonists. Cancer Cell, 23: 23-34, 2013

Takahashi, T., Shivapurkar, N., Reddy, J., Shigematsu, H., Miyajima, K., Suzuki, M., Toyooka, S., Zochbauer-Muller, S., Drach, J., Parikh, G., Zheng, Y., Feng, Z., Kroft, S.H., Timmons, C., McKenna, R.W., Gazdar, A.F., Retraction: DNA methylation profiles of lymphoid and hematopoietic malignancies. Clin Cancer Res, 19: 307, 2013

Li, X., Zhou, Q., Hanus, J., Anderson, C., Zhang, H., Dellinger, M., Brekken, R., Wang, S., Inhibition of multiple pathogenic pathways by histone deacetylase inhibitor SAHA in a corneal alkali-burn injury model. Mol Pharm, 10: 307-18, 2013

Yoshida, K., Sato, M., Hase, T., Elshazley, M., Yamashita, R., Usami, N., Taniguchi, T., Yokoi, K., Nakamura, S., Kondo, M., Girard, L., Minna, J.D., Hasegawa, Y., TIMELESS is overexpressed in lung cancer and its expression correlates with poor patient survival. Cancer Sci, 104: 171-7, 2013

Byers, L.A., Diao, L., Wang, J., Saintigny, P., Girard, L., Peyton, M., Shen, L., Fan, Y., Giri, U., Tumula, P.K., Nilsson, M.B., Gudikote, J., Tran, H., Cardnell, R.J., Bearss, D.J., Warner, S.L., Foulks, J.M., Kanner, S.B., Gandhi, V., Krett, N., Rosen, S.T., Kim, E.S., Herbst, R.S., Blumenschein, G.R., Lee, J.J., Lippman, S.M., Ang, K.K., Mills, G.B., Hong, W.K., Weinstein, J.N., Wistuba, II, Coombes, K.R., Minna, J.D., Heymach, J.V., An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance. Clin Cancer Res, 19: 279-90, 2013

Travis, W.D., Brambilla, E., Noguchi, M., Nicholson, A.G., Geisinger, K., Yatabe, Y., Ishikawa, Y., Wistuba, I., Flieder, D.B., Franklin, W., Gazdar, A., Hasleton, P.S., Henderson, D.W., Kerr, K.M., Petersen, I., Roggli, V., Thunnissen, E., Tsao, M., Diagnosis of lung cancer in small biopsies and cytology: Implications of the 2011 International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society classification. Arch Pathol Lab Med, 137: 668-84, 2013

Dasgupta, S., Jang, J.S., Shao, C., Mukhopadhyay, N.D., Sokhi, U.K., Das, S.K., Brait, M., Talbot, C., Yung, R.C., Begum, S., Westra, W.H., Hoque, M.O., Yang, P., Yi, J.E., Lam, S., Gazdar, A.F., Fisher, P.B., Jen, J., Sidransky, D., SH3GL2 is frequently deleted in non-small cell lung cancer and downregulates tumor growth by modulating EGFR signaling. J Mol Med (Berl), 91: 381-93, 2013

Sunaga, N., Kaira, K., Imai, H., Shimizu, K., Nakano, T., Shames, D.S., Girard, L., Soh, J., Sato, M., Iwasaki, Y., Ishizuka, T., Gazdar, A.F., Minna, J.D., Mori, M., Oncogenic KRAS-induced epiregulin overexpression contributes to aggressive phenotype and is a promising therapeutic target in non-small-cell lung cancer. Oncogene, 32: 4034-42, 2013

Sugalski, A., Davis, M., Prasannan, L., Saldivar, V., Hung, J.Y., Tomlinson, G.E., Clinical, histologic, and genetic features of mesothelioma in a 7-year-old child. Pediatr Blood Cancer, 60: 146-8, 2013

Travis, W.D., Brambilla, E., Noguchi, M., Nicholson, A.G., Geisinger, K., Yatabe, Y., Ishikawa, Y., Wistuba, I., Flieder, D.B., Franklin, W., Gazdar, A., Hasleton, P.S., Henderson, D.W., Kerr, K.M., Nakatani, Y., Petersen, I., Roggli, V., Thunnissen, E., Tsao, M., Diagnosis of lung adenocarcinoma in resected specimens: implications of the 2011 International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society classification. Arch Pathol Lab Med, 137: 685-705, 2013

2012

Hu, Y., Martinez, E.D., MacMillan, J.B., Anthraquinones from a marine-derived Streptomyces spinoverrucosus. J Nat Prod, 75: 1759-64, 2012

Liu, J., Lee, W., Jiang, Z., Chen, Z., Jhunjhunwala, S., Haverty, P.M., Gnad, F., Guan, Y., Gilbert, H.N., Stinson, J., Klijn, C., Guillory, J., Bhatt, D., Vartanian, S., Walter, K., Chan, J., Holcomb, T., Dijkgraaf, P., Johnson, S., Koeman, J., Minna, J.D., Gazdar, A.F., Stern, H.M., Hoeflich, K.P., Wu, T.D., Settleman, J., de Sauvage, F.J., Gentleman, R.C., Neve, R.M., Stokoe, D., Modrusan, Z., Seshagiri, S., Shames, D.S., Zhang, Z., Genome and transcriptome sequencing of lung cancers reveal diverse mutational and splicing events. Genome Res, 22: 2315-27, 2012

Byers, L.A., Wang, J., Nilsson, M.B., Fujimoto, J., Saintigny, P., Yordy, J., Giri, U., Peyton, M., Fan, Y.H., Diao, L., Masrorpour, F., Shen, L., Liu, W., Duchemann, B., Tumula, P., Bhardwaj, V., Welsh, J., Weber, S., Glisson, B.S., Kalhor, N., Wistuba, II, Girard, L., Lippman, S.M., Mills, G.B., Coombes, K.R., Weinstein, J.N., Minna, J.D., Heymach, J.V., Proteomic profiling identifies dysregulated pathways in small cell lung cancer and novel therapeutic targets including PARP1. Cancer Discov, 2: 798-811, 2012

Rudin, C.M., Durinck, S., Stawiski, E.W., Poirier, J.T., Modrusan, Z., Shames, D.S., Bergbower, E.A., Guan, Y., Shin, J., Guillory, J., Rivers, C.S., Foo, C.K., Bhatt, D., Stinson, J., Gnad, F., Haverty, P.M., Gentleman, R., Chaudhuri, S., Janakiraman, V., Jaiswal, B.S., Parikh, C., Yuan, W., Zhang, Z., Koeppen, H., Wu, T.D., Stern, H.M., Yauch, R.L., Huffman, K.E., Paskulin, D.D., Illei, P.B., Varella-Garcia, M., Gazdar, A.F., de Sauvage, F.J., Bourgon, R., Minna, J.D., Brock, M.V., Seshagiri, S., Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer. Nat Genet, 2012

Gerber, D.E., Gupta, P., Dellinger, M.T., Toombs, J.E., Peyton, M., Duignan, I., Malaby, J., Bailey, T., Burns, C., Brekken, R.A., Loizos, N., Stromal platelet-derived growth factor receptor alpha (PDGFRalpha) provides a therapeutic target independent of tumor cell PDGFRalpha expression in lung cancer xenografts. Mol Cancer Ther, 2012

Sharma, V., Shivalingaiah, S., Peng, Y., Euhus, D., Gryczynski, Z., Liu, H., Auto-fluorescence lifetime and light reflectance spectroscopy for breast cancer diagnosis: potential tools for intraoperative margin detection. Biomed Opt Express, 3: 1825-40, 2012

Kirane, A., Toombs, J.E., Ostapoff, K., Carbon, J.G., Zaknoen, S., Braunfeld, J., Schwarz, R.E., Burrows, F.J., Brekken, R.A., Apricoxib, a Novel Inhibitor of COX-2, Markedly Improves Standard Therapy Response in Molecularly Defined Models of Pancreatic Cancer. Clin Cancer Res, 18: 5031-42, 2012

Thunnissen, E., Beasley, M.B., Borczuk, A.C., Brambilla, E., Chirieac, L.R., Dacic, S., Flieder, D., Gazdar, A., Geisinger, K., Hasleton, P., Ishikawa, Y., Kerr, K.M., Lantejoul, S., Matsuno, Y., Minami, Y., Moreira, A.L., Motoi, N., Nicholson, A.G., Noguchi, M., Nonaka, D., Pelosi, G., Petersen, I., Rekhtman, N., Roggli, V., Travis, W.D., Tsao, M.S., Wistuba, I., Xu, H., Yatabe, Y., Zakowski, M., Witte, B., Kuik, D.J., Reproducibility of histopathological subtypes and invasion in pulmonary adenocarcinoma. An international interobserver study. Mod Pathol, 2012

Tomlinson, G.E., Kappler, R., Genetics and epigenetics of hepatoblastoma. Pediatr Blood Cancer, 59: 785-92, 2012

Hezel, A.F., Deshpande, V., Zimmerman, S.M., Contino, G., Alagesan, B., O'Dell, M.R., Rivera, L.B., Harper, J., Lonning, S., Brekken, R.A., Bardeesy, N., TGF-beta and alphavbeta6 Integrin Act in a Common Pathway to Suppress Pancreatic Cancer Progression. Cancer Res, 72: 4840-5, 2012

Du, L., Subauste, M.C., DeSevo, C., Zhao, Z., Baker, M., Borkowski, R., Schageman, J.J., Greer, R., Yang, C.R., Suraokar, M., Wistuba, II, Gazdar, A.F., Minna, J.D., Pertsemlidis, A., miR-337-3p and its targets STAT3 and RAP1A modulate taxane sensitivity in non-small cell lung cancers. PLoS One, 7: e39167, 2012

Awasthi, N., Zhang, C., Ruan, W., Schwarz, M.A., Schwarz, R.E., Evaluation of poly-mechanistic antiangiogenic combinations to enhance cytotoxic therapy response in pancreatic cancer. PLoS One, 7: e38477, 2012

Yao, Y., Fan, Y., Wu, J., Wan, H., Wang, J., Lam, S., Lam, W.L., Girard, L., Gazdar, A.F., Wu, Z., Zhou, Q., Potential application of non-small cell lung cancer-associated autoantibodies to early cancer diagnosis. Biochem Biophys Res Commun, 423: 613-9, 2012

Hu, J., Lu, J.Y., Wong, A.M., Hynan, L.S., Birnbaum, S.G., Yilmaz, D.S., Streit, B.M., Lenartowicz, E.M., Thompson, T.C., Cooper, J.D., Hofmann, S.L., Intravenous high-dose enzyme replacement therapy with recombinant palmitoyl-protein thioesterase reduces visceral lysosomal storage and modestly prolongs survival in a preclinical mouse model of infantile neuronal ceroid lipofuscinosis. Mol Genet Metab, 107: 213-21, 2012

Jeong, Y., Xie, Y., Lee, W., Bookout, A.L., Girard, L., Raso, G., Behrens, C., Wistuba, II, Gazdar, A.F., Minna, J.D., Mangelsdorf, D.J., Research resource: Diagnostic and therapeutic potential of nuclear receptor expression in lung cancer. Mol Endocrinol, 26: 1443-54, 2012

Chlebowski, R.T., McTiernan, A., Wactawski-Wende, J., Manson, J.E., Aragaki, A.K., Rohan, T., Ipp, E., Kaklamani, V.G., Vitolins, M., Wallace, R., Gunter, M., Phillips, L.S., Strickler, H., Margolis, K., Euhus, D.M., Diabetes, metformin, and breast cancer in postmenopausal women. J Clin Oncol, 30: 2844-52, 2012

Kirane, A., Toombs, J.E., Larsen, J.E., Ostapoff, K.T., Meshaw, K.R., Zaknoen, S., Brekken, R.A., Burrows, F.J., Epithelial-mesenchymal transition increases tumor sensitivity to COX-2 inhibition by apricoxib. Carcinogenesis, 33: 1639-46, 2012

Lockwood, W.W., Wilson, I.M., Coe, B.P., Chari, R., Pikor, L.A., Thu, K.L., Solis, L.M., Nunez, M.I., Behrens, C., Yee, J., English, J., Murray, N., Tsao, M.S., Minna, J.D., Gazdar, A.F., Wistuba, II, MacAulay, C.E., Lam, S., Lam, W.L., Divergent genomic and epigenomic landscapes of lung cancer subtypes underscore the selection of different oncogenic pathways during tumor development. PLoS One, 7: e37775, 2012

Selamat, S.A., Chung, B.S., Girard, L., Zhang, W., Zhang, Y., Campan, M., Siegmund, K.D., Koss, M.N., Hagen, J.A., Lam, W.L., Lam, S., Gazdar, A.F., Laird-Offringa, I.A., Genome-scale analysis of DNA methylation in lung adenocarcinoma and integration with mRNA expression. Genome Res, 22: 1197-1211, 2012

Lynn, K.D., Brekken, R.A., Anti-VEGF therapy revived by c-Met inhibition, but is c-Met the answer? Cancer Discov, 2: 211-3, 2012

Elshazley, M., Sato, M., Hase, T., Yamashita, R., Yoshida, K., Toyokuni, S., Ishiguro, F., Osada, H., Sekido, Y., Yokoi, K., Usami, N., Shames, D.S., Kondo, M., Gazdar, A.F., Minna, J.D., Hasegawa, Y., The circadian clock gene BMAL1 is a novel therapeutic target for malignant pleural mesothelioma. Int J Cancer, 2012

Asterholm, I.W., McDonald, J., Blanchard, P.G., Sinha, M., Xiao, Q., Mistry, J., Rutkowski, J.M., Deshaies, Y., Brekken, R.A., Scherer, P.E., Lack of "immunological fitness" during fasting in metabolically challenged animals. J Lipid Res, 53: 1254-67, 2012

Sun, K., Asterholm, I.W., Kusminski, C.M., Bueno, A.C., Wang, Z.V., Pollard, J.W., Brekken, R.A., Scherer, P.E., Dichotomous effects of VEGF-A on adipose tissue dysfunction. Proc Natl Acad Sci U S A, 2012

Schwarz, M.A., Thornton, J., Xu, H., Awasthi, N., Schwarz, R.E., Cell proliferation and migration are modulated by Cdk-1-phosphorylated endothelial-monocyte activating polypeptide II. PLoS One, 7: e33101, 2012

Thu, K.L., Vucic, E.A., Chari, R., Zhang, W., Lockwood, W.W., English, J.C., Fu, R., Wang, P., Feng, Z., Macaulay, C.E., Gazdar, A.F., Lam, S., Lam, W.L., Lung adenocarcinoma of never smokers and smokers harbor differential regions of genetic alteration and exhibit different levels of genomic instability. PloS one, 7: e33003, 2012

Euhus, D., Managing the breast in patients who test positive for hereditary breast cancer. Ann Surg Oncol, 19: 1738-44, 2012

Masciari, S., Dillon, D.A., Rath, M., Robson, M., Weitzel, J.N., Balmana, J., Gruber, S.B., Ford, J.M., Euhus, D., Lebensohn, A., Telli, M., Pochebit, S.M., Lypas, G., Garber, J.E., Breast cancer phenotype in women with TP53 germline mutations: a Li-Fraumeni syndrome consortium effort. Breast Cancer Res Treat, 133: 1125-30, 2012

Xie, Y., Minna, J.D., A lung cancer molecular prognostic test ready for prime time. Lancet, 379: 785-7, 2012

Arnold, S.A., Rivera, L.B., Carbon, J.G., Toombs, J.E., Chang, C.L., Bradshaw, A.D., Brekken, R.A., Losartan slows pancreatic tumor progression and extends survival of SPARC-null mice by abrogating aberrant TGF beta activation. PLoS One, 7: e31384, 2012

Li, G., Guillaud, M., le Riche, J., McWilliams, A., Gazdar, A., Lam, S., Macaulay, C., Automated sputum cytometry for detection of intraepithelial neoplasias in the lung. Analytical cellular pathology, 2012

Benson, D.D., Beck, A.W., Burdine, M.S., Brekken, R., Silliman, C.C., Barnett, C.C., Jr., Accumulation of pro-cancer cytokines in the plasma fraction of stored packed red cells. J Gastrointest Surg, 16: 460-8, 2012

Tomlinson, G.E., Cytogenetics of hepatoblastoma. Front Biosci (Elite Ed), 4: 1287-92, 2012

Allen, J.D., Wang, S., Chen, M., Girard, L., Minna, J.D., Xie, Y., Xiao, G., Probe mapping across multiple microarray platforms. Brief Bioinform, 13: 547-54, 2012

Chang, J., Varghese, D.S., Gillam, M.C., Peyton, M., Modi, B., Schiltz, R.L., Girard, L., Martinez, E.D., Differential response of cancer cells to HDAC inhibitors trichostatin A and depsipeptide. Br J Cancer, 106: 116-25, 2012

Horio, M., Sato, M., Takeyama, Y., Elshazley, M., Yamashita, R., Hase, T., Yoshida, K., Usami, N., Yokoi, K., Sekido, Y., Kondo, M., Toyokuni, S., Gazdar, A.F., Minna, J.D., Hasegawa, Y., Transient but Not Stable ZEB1 Knockdown Dramatically Inhibits Growth of Malignant Pleural Mesothelioma Cells. Ann Surg Oncol, 19 Suppl 3: 634-45, 2012

Li, Y., Martin, B.R., Cravatt, B.F., Hofmann, S.L., DHHC5 protein palmitoylates flotillin-2 and is rapidly degraded on induction of neuronal differentiation in cultured cells. J Biol Chem, 287: 523-30, 2012

Kirov, A., Al-Hashimi, H., Solomon, P., Mazur, C., Thorpe, P.E., Sims, P.J., Tarantini, F., Kumar, T.K., Prudovsky, I., Phosphatidylserine externalization and membrane blebbing are involved in the nonclassical export of FGF1. J Cell Biochem, 113: 956-66, 2012

Awasthi, N., Yen, P.L., Schwarz, M.A., Schwarz, R.E., The efficacy of a novel, dual PI3K/mTOR inhibitor NVP-BEZ235 to enhance chemotherapy and antiangiogenic response in pancreatic cancer. J Cell Biochem, 113: 784-91, 2012

Dasgupta, S., Soudry, E., Mukhopadhyay, N., Shao, C., Yee, J., Lam, S., Lam, W., Zhang, W., Gazdar, A.F., Fisher, P.B., Sidransky, D., Mitochondrial DNA mutations in respiratory complex-I in never-smoker lung cancer patients contribute to lung cancer progression and associated with EGFR gene mutation. Journal of cellular physiology, 227: 2451-60, 2012

Sunaga, N., Imai, H., Shimizu, K., Shames, D.S., Kakegawa, S., Girard, L., Sato, M., Kaira, K., Ishizuka, T., Gazdar, A.F., Minna, J.D., Mori, M., Oncogenic KRAS-induced interleukin-8 overexpression promotes cell growth and migration and contributes to aggressive phenotypes of non-small cell lung cancer. International journal of cancer. Journal international du cancer, 130: 1733-44, 2012

Carbone, M., Ly, B.H., Dodson, R.F., Pagano, I., Morris, P.T., Dogan, U.A., Gazdar, A.F., Pass, H.I., Yang, H., Malignant mesothelioma: facts, myths, and hypotheses. J Cell Physiol, 227: 44-58, 2012

2011

Zhao, D, Stafford, JH, Zhou, H, Thorpe, PE: Near-infrared Optical Imaging of Exposed Phosphatidylserine in a Mouse Glioma Model. Transl Oncol 4:355-64, 2011

Dellinger, MT, Brekken, RA: Phosphorylation of Akt and ERK1/2 is required for VEGF-A/VEGFR2-induced proliferation and migration of lymphatic endothelium. PLoS One 6:e28947, 2011

Gazdar, AF, Schiller, JH: Predictive and Prognostic Factors for Non-Small Cell Lung Cancer--Potholes in the Road to the Promised Land. J Natl Cancer Inst, 2011

Larsen, JE, Cascone, T, Gerber, DE, Heymach, JV, Minna, JD: Targeted therapies for lung cancer: clinical experience and novel agents. Cancer J 17:512-27, 2011

Gazdar, AF, Zhang, YA: Research highlights. Epigenomics 3:405-7, 2011

Gazdar, AF, Brambilla, E: Preneoplasia of lung cancer. Cancer Biomark 9:385-96, 2011

Horio, M, Sato, M, Takeyama, Y, Elshazley, M, Yamashita, R, Hase, T, Yoshida, K, Usami, N, Yokoi, K, Sekido, Y, Kondo, M, Toyokuni, S, Gazdar, AF, Minna, JD, Hasegawa, Y: Transient but Not Stable ZEB1 Knockdown Dramatically Inhibits Growth of Malignant Pleural Mesothelioma Cells. Ann Surg Oncol, 2011

Toyooka, S, Gazdar, AF: Methylation profiling of lung cancer: a decade of progress. Mol Cancer Ther 10:2020, 2011

Larsen, JE, Minna, JD: Molecular biology of lung cancer: clinical implications. Clin Chest Med 32:703-40, 2011

Lam, DC, Minna, JD: How do we safely get people to stop smoking? Cancer Prev Res (Phila) 4:1724-7, 2011

Greer, RM, Peyton, M, Larsen, JE, Girard, L, Xie, Y, Gazdar, AF, Harran, P, Wang, L, Brekken, RA, Wang, X, Minna, JD: SMAC mimetic (JP1201) sensitizes non-small cell lung cancers to multiple chemotherapy agents in an IAP-dependent but TNF-alpha-independent manner. Cancer Res 71:7640-8, 2011

Gerber, DE, Stopeck, AT, Wong, L, Rosen, LS, Thorpe, PE, Shan, JS, Ibrahim, NK: Phase I safety and pharmacokinetic study of bavituximab, a chimeric phosphatidylserine-targeting monoclonal antibody, in patients with advanced solid tumors. Clin Cancer Res 17:6888-96, 2011

Starczynowski, DT, Lockwood, WW, Delehouzee, S, Chari, R, Wegrzyn, J, Fuller, M, Tsao, MS, Lam, S, Gazdar, AF, Lam, WL, Karsan, A: TRAF6 is an amplified oncogene bridging the RAS and NF-kappaB pathways in human lung cancer. J Clin Invest, 2011

Taguchi, A, Politi, K, Pitteri, SJ, Lockwood, WW, Faca, VM, Kelly-Spratt, K, Wong, CH, Zhang, Q, Chin, A, Park, KS, Goodman, G, Gazdar, AF, Sage, J, Dinulescu, DM, Kucherlapati, R, Depinho, RA, Kemp, CJ, Varmus, HE, Hanash, SM: Lung cancer signatures in plasma based on proteome profiling of mouse tumor models. Cancer Cell 20:289-99, 2011

Shay, JW, Cucinotta, FA, Sulzman, FM, Coleman, CN, Minna, JD: From mice and men to earth and space: joint NASA-NCI workshop on lung cancer risk resulting from space and terrestrial radiation. Cancer Res 71:6926-9, 2011

Nomura, M, Fukuda, T, Fujii, K, Kawamura, T, Tojo, H, Kihara, M, Bando, Y, Gazdar, AF, Tsuboi, M, Oshiro, H, Nagao, T, Ohira, T, Ikeda, N, Gotoh, N, Kato, H, Marko-Varga, G, Nishimura, T: Preferential expression of potential markers for cancer stem cells in large cell neuroendocrine carcinoma of the lung. An FFPE proteomic study. J Clin Bioinforma 1:23, 2011

Girotti, MR, Fernandez, M, Lopez, JA, Camafeita, E, Fernandez, EA, Albar, JP, Benedetti, LG, Valacco, MP, Brekken, RA, Podhajcer, OL, Llera, AS: SPARC promotes cathepsin B-mediated melanoma invasiveness through a collagen I/alpha2beta1 integrin axis. J Invest Dermatol 131:2438-47, 2011

Awasthi, N, Schwarz, MA, Schwarz, RE: Antitumour activity of sunitinib in combination with gemcitabine in experimental pancreatic cancer. HPB (Oxford) 13:597-604, 2011

DeRose, P, Thorpe, PE, Gerber, DE: Development of bavituximab, a vascular targeting agent with immune-modulating properties, for lung cancer treatment. Immunotherapy 3:933-44, 2011

Dasgupta, S, Soudry, E, Mukhopadhyay, N, Shao, C, Yee, J, Lam, S, Lam, W, Zhang, W, Gazdar, AF, Fisher, PB, Sidransky, D: Mitochondrial DNA mutations in respiratory complex-I in never-smoker lung cancer patients contribute to lung cancer progression and associated with EGFR gene mutation. J Cell Physiol, 2011

Rivera, LB, Bradshaw, AD, Brekken, RA: The regulatory function of SPARC in vascular biology. Cell Mol Life Sci 68:3165-73, 2011

Thu, KL, Pikor, LA, Chari, R, Wilson, IM, Macaulay, CE, English, JC, Tsao, MS, Gazdar, AF, Lam, S, Lam, WL, Lockwood, WW: Genetic Disruption of KEAP1/CUL3 E3 Ubiquitin Ligase Complex Components is a Key Mechanism of NF-KappaB Pathway Activation in Lung Cancer. J Thorac Oncol 6:1521-1529, 2011

Euhus, D, Bu, D, Xie, XJ, Sarode, V, Ashfaq, R, Hunt, K, Xia, W, O'Shaughnessy, J, Grant, M, Arun, B, Dooley, W, Miller, A, Flockhart, D, Lewis, C: Tamoxifen downregulates ets oncogene family members ETV4 and ETV5 in benign breast tissue: implications for durable risk reduction. Cancer Prev Res (Phila) 4:1852-62, 2011

Zhang, YA, Maitra, A, Hsieh, JT, Rudin, CM, Peacock, C, Karikari, C, Brekken, RA, Stastny, V, Gao, B, Girard, L, Wistuba, I, Frenkel, E, Minna, JD, Gazdar, AF: Frequent detection of infectious xenotropic murine leukemia virus (XMLV) in human cultures established from mouse xenografts. Cancer Biol Ther 12, 2011

Zhang, YA, Maitra, A, Hsieh, JT, Rudin, CM, Peacock, CD, Karikari, C, Brekken, RA, Stastny, V, Gao, B, Girard, L, Wistuba, I, Frenkel, E, Minna, JD, Gazdar, AF: Frequent detection of infectious xenotropic murine leukemia virus (XMLV) in human cultures established from mouse xenografts. Cancer Biol Ther 12:617-28, 2011

Xie, Y, Xiao, G, Coombes, KR, Behrens, C, Solis, LM, Raso, G, Girard, L, Erickson, HS, Roth, J, Heymach, JV, Moran, C, Danenberg, K, Minna, JD, Wistuba, II: Robust gene expression signature from formalin-fixed paraffin-embedded samples predicts prognosis of non-small-cell lung cancer patients. Clin Cancer Res 17:5705-14, 2011

Rivera, LB, Brekken, RA: SPARC promotes pericyte recruitment via inhibition of endoglin-dependent TGF-beta1 activity. J Cell Biol 193:1305-19, 2011

Harris, BS, Zhang, Y, Card, L, Rivera, LB, Brekken, RA, Bradshaw, AD: SPARC regulates collagen interaction with cardiac fibroblast cell surfaces. Am J Physiol Heart Circ Physiol 301:H841-7, 2011

Huang, X, Ye, D, Thorpe, PE: Enhancing the potency of a whole-cell breast cancer vaccine in mice with an antibody-IL-2 immunocytokine that targets exposed phosphatidylserine. Vaccine 29:4785-93, 2011

Hill, VK, Ricketts, C, Bieche, I, Vacher, S, Gentle, D, Lewis, C, Maher, ER, Latif, F: Genome-wide DNA methylation profiling of CpG islands in breast cancer identifies novel genes associated with tumorigenicity. Cancer Res 71:2988-99, 2011

Galindo, CL, McIver, LJ, Tae, H, McCormick, JF, Skinner, MA, Hoeschele, I, Lewis, CM, Minna, JD, Boothman, DA, Garner, HR: Sporadic breast cancer patients' germline DNA exhibit an AT-rich microsatellite signature. Genes Chromosomes Cancer 50:275-83, 2011

Hogg, RT, Thorpe, P, Gerard, RD: Retargeting adenoviral vectors to improve gene transfer into tumors. Cancer Gene Ther 18:275-87, 2011

Ramesh, S, Morrell, CN, Tarango, C, Thomas, GD, Yuhanna, IS, Girardi, G, Herz, J, Urbanus, RT, de Groot, PG, Thorpe, PE, Salmon, JE, Shaul, PW, Mineo, C: Antiphospholipid antibodies promote leukocyte-endothelial cell adhesion and thrombosis in mice by antagonizing eNOS via beta2GPI and apoER2. J Clin Invest 121:120-31, 2011

Awasthi, N, Schwarz, MA, Schwarz, RE: Enhancing cytotoxic agent activity in experimental pancreatic cancer through EMAP II combination therapy. Cancer Chemother Pharmacol 68:571-82, 2011

Vasalatiy, O, Zhao, P, Woods, M, Marconescu, A, Castillo-Muzquiz, A, Thorpe, P, Kiefer, GE, Sherry, AD: Strategies for labeling proteins with PARACEST agents. Bioorg Med Chem 19:1106-14, 2011

Liang, Y, Besch-Williford, C, Benakanakere, I, Thorpe, PE, Hyder, SM: Targeting mutant p53 protein and the tumor vasculature: an effective combination therapy for advanced breast tumors. Breast Cancer Res Treat 125:407-20, 2011

Sunaga N, Imai H, Shimizu K, Shames DS, Kakegawa S, Girard L, Sato M, Kaira K, Ishizuka T, Gazdar AF, Minna JD, Mori M: Oncogenic KRAS-induced interleukin-8 overexpression promotes cell growth and migration and contributes to aggressive phenotypes of non-small cell lung cancer. International Journal of Cancer, 2011

Hase T, Sato M, Yoshida K, Girard L, Takeyama Y, Horio M, Elshazley M, Oguri T, Sekido Y, Shames DS, Gazdar AF, Minna JD, Kondo M, Hasegawa Y: A Pivotal Role for Epithelial Cell Adhesion Molecule (EpCAM) in the Survival of Lung Cancer Cells. Cancer Science, 2011

Gazdar AF: Tyrosine Kinase Inhibitors and Epidermal Growth Factor Receptor (EGFR) Mutations in Non-Small Cell Lung Cancer: To Test or Not to Test? Medicine (Baltimore) 90:168-70, 2011

Sierko E, Wojtukiewicz MZ, Zimnoch L, Thorpe PE, Brekken RA, Kisiel W: Co-localization of Prothrombin Fragment F1+2 and VEGF-R2-Bound VEGF in Human Colon Cancer. Anticancer Research 31:843-7, 2011

Stafford JH, Thorpe PE: Increased exposure of phosphatidylethanolamine on the surface of tumor vascular endothelium. Neoplasia 13:299-308, 2011

Carbone M, Ly BH, Dodson RF, Pagano I, Morris PT, Dogan UA, Gazdar AF, Pass HI, Yang H:Malignant mesothelioma: Facts, myths and hypotheses. Journal of Cellular Physiology, 2011

Euhus DM: New insights into the prevention and treatment of familial breast cancer. Journal of Surgical Oncology 103:294-8, 2011

Ou YH, Torres M, Ram R, Formstecher E, Roland C, Cheng T, Brekken R, Wurz R, Tasker A, Polverino T, Tan SL, White MA: TBK1 directly engages Akt/PKB survival signaling to support oncogenic transformation. Molecular Cell 41:458-70, 2011

Sunaga N, Shames DS, Girard L, Peyton M, Larsen JE, Imai H, Soh J, Sato M, Yanagitani N, Kaira K, Xie Y, Gazdar AF, Mori M, Minna JD: Knockdown of oncogenic KRAS in non-small cell lung cancers suppresses tumor growth and sensitizes tumor cells to targeted therapy. Molecular Cancer Theraputics 10:336-46, 2011

Schwarz RE: Challenges with demographic disparities in gastric cancer care and survival: spectral rather than black and white. Cancer Epidemiology Biomarkers and Prevention 20:221-2, 2011

Tang X, Kadara H, Behrens C, Liu D, Xiao Y, Rice DC, Gazdar AF, Fujimoto J, Moran C, Varella-Garcia M, Lee JJ, Hong WK, Wistuba, II: Abnormalities of the TITF-1 lineage-specific oncogene in NSCLC: Implications in lung cancer pathogenesis and prognosis. Clinical Cancer Research, 2011

Travis WD, Brambilla E, Noguchi M, Nicholson AG, Geisinger KR, Yatabe Y, Beer DG, Powell CA, Riely GJ, Van Schil PE, Garg K, Austin JH, Asamura H, Rusch VW, Hirsch FR, Scagliotti G, Mitsudomi T, Huber RM, Ishikawa Y, Jett J, Sanchez-Cespedes M, Sculier JP, Takahashi T, Tsuboi M, Vansteenkiste J, Wistuba I, Yang PC, Aberle D, Brambilla C, Flieder D, Franklin W, Gazdar A, Gould M, Hasleton P, Henderson D, Johnson B, Johnson D, Kerr K, Kuriyama K, Lee JS, Miller VA, Petersen I, Roggli V, Rosell R, Saijo N, Thunnissen E, Tsao M, Yankelewitz D:International association for the study of lung cancer/american thoracic society/European Respiratory Society international multidisciplinary classification of lung adenocarcinoma. Journal of Thoracic Oncology 6:244-85, 2011

Best AM, Chang J, Dull AB, Beutler JA, Martinez ED: Identification of four potential epigenetic modulators from the NCI structural diversity library using a cell-based assay. Journal of Biomedicine and Biotechnology:868095, 2011

Awasthi N, Kirane A, Schwarz MA, Toombs JE, Brekken RA, Schwarz RE: Smac mimetic-derived augmentation of chemotherapeutic response in experimental pancreatic cancer. Biomed Central 11:15, 2011

Li LS, Bey EA, Dong Y, Meng J, Patra B, Yan J, Xie XJ, Brekken RA, Barnett CC, Bornmann WG, Gao J, Boothman DA: Modulating endogenous NQO1 levels identifies key regulatory mechanisms of action of beta-lapachone for pancreatic cancer therapy. Clinical Cancer Research 17:275-85, 2011

Chandra M, Zhou H, Li Q, Muallem S, Hofmann SL, Soyombo AA: A role for the Ca2+ channel TRPML1 in gastric acid secretion, based on analysis of knockout mice. Gastroenterology 140:857-67, 2011

Rule W, Timmerman R, Tong L, Abdulrahman R, Meyer J, Boike T, Schwarz RE, Weatherall P, Chinsoo Cho L: Phase I dose-escalation study of stereotactic body radiotherapy in patients with hepatic metastases. Annals of Surgical Oncology 18:1081-7, 2011

Mansour JC, Schwarz RE: Resection of type I gastric carcinoid: when and why? Journal of Surgical Research 166:68-9, 2011

Yamaguchi S, Jha A, Li Q, Soyombo AA, Dickinson GD, Churamani D, Brailoiu E, Patel S, Muallem S: TRPML1 and the two-pore channels are functionally independent organellar ion channels. Journal of Biological Chemistry, 2011

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2010

Tokuyama Y, Takahashi T, Okumura N, Nonaka K, Kawaguchi Y, Yamaguchi K, Osada S, Gazdar A, Yoshida K: Aberrant methylation of heparan sulfate glucosamine 3-O-sulfotransferase 2 genes as a biomarker in colorectal cancer. Anticancer Research 30:4811-8, 2010

Jeong Y, Xie Y, Xiao G, Behrens C, Girard L, Wistuba, II, Minna JD, Mangelsdorf DJ: Nuclear receptor expression defines a set of prognostic biomarkers for lung cancer. PLoS Medicine 7:e1000378, 2010

Gerber DE, Minna JD: ALK inhibition for non-small cell lung cancer: from discovery to therapy in record time. Cancer Cell 18:548-51, 2010

Sullivan JP, Spinola M, Dodge M, Raso MG, Behrens C, Gao B, Schuster K, Shao C, Larsen JE, Sullivan LA, Honorio S, Xie Y, Scaglioni PP, DiMaio JM, Gazdar AF, Shay JW, Wistuba, II, Minna JD: Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling. Cancer Research 70:9937-48, 2010

Chandra M, Zhou H, Li Q, Muallem S, Hofmann SL, Soyombo AA: A Role for the Ca(2+) Channel TRPML1 in Gastric Acid Secretion, Based on Analysis of Knockout Mice. Gastroenterology, 2010

Awasthi N, Schwarz MA, Schwarz RE: Enhancing cytotoxic agent activity in experimental pancreatic cancer through EMAP II combination therapy. Cancer Chemotherapy and Pharmacology, 2010

Ramos AL, Darabi R, Akbarloo N, Borges L, Catanese J, Dineen SP, Brekken RA, Perlingeiro RC: Clonal analysis reveals a common progenitor for endothelial, myeloid, and lymphoid precursors in umbilical cord blood. Circulation Research 107:1460-9, 2010

Gazdar AF: Should we continue to use the term non-small-cell lung cancer? Annals of Oncology 21 Suppl 7:vii225-vii229, 2010

Xie Y, Minna JD: Non-small-cell lung cancer mRNA expression signature predicting response to adjuvant chemotherapy. Journal of Clinical Oncology 28:4404-7, 2010

De Leon-Rodriguez LM, Lubag A, Udugamasooriya DG, Proneth B, Brekken RA, Sun X, Kodadek T, Dean Sherry A: MRI detection of VEGFR2 in vivo using a low molecular weight peptoid-(Gd)8-dendron for targeting. Journal of the American Chemical Society 132:12829-31, 2010

Sullivan LA, Carbon JG, Roland CL, Toombs JE, Nyquist-Andersen M, Kavlie A, Schlunegger K, Richardson JA, Brekken RA: r84, a novel therapeutic antibody against mouse and human VEGF with potent anti-tumor activity and limited toxicity induction. PLoS One 5:e12031, 2010

Das AK, Bell MH, Nirodi CS, Story MD, Minna JD: Radiogenomics predicting tumor responses to radiotherapy in lung cancer. Seminars in Radiation Oncology 20:149-55, 2010

Saha D, Watkins L, Yin Y, Thorpe P, Story MD, Song K, Raghavan P, Timmerman R, Chen B, Minna JD, Solberg TD: An orthotopic lung tumor model for image-guided microirradiation in rats. Radiation Research 174:62-71, 2010

Gazdar AF, Girard L, Lockwood WW, Lam WL, Minna JD: Lung cancer cell lines as tools for biomedical discovery and research. Journal of the National Cancer Institute 102:1310-21, 2010

Lynn KD, Udugamasooriya DG, Roland CL, Castrillon DH, Kodadek TJ, Brekken RA: GU81, a VEGFR2 antagonist peptoid, enhances the anti-tumor activity of doxorubicin in the murine MMTV-PyMT transgenic model of breast cancer. Biomed Central 10:397, 2010

Lockwood WW, Chari R, Coe BP, Thu KL, Garnis C, Malloff CA, Campbell J, Williams AC, Hwang D, Zhu CQ, Buys TP, Yee J, English JC, Macaulay C, Tsao MS, Gazdar AF, Minna JD, Lam S, Lam WL: Integrative genomic analyses identify BRF2 as a novel lineage-specific oncogene in lung squamous cell carcinoma. PLoS Medicine 7:e1000315, 2010

Cai D, Shames DS, Raso MG, Xie Y, Kim YH, Pollack JR, Girard L, Sullivan JP, Gao B, Peyton M, Nanjundan M, Byers L, Heymach J, Mills G, Gazdar AF, Wistuba I, Kodadek T, Minna JD:Steroid receptor coactivator-3 expression in lung cancer and its role in the regulation of cancer cell survival and proliferation. Cancer Research 70:6477-85, 2010

Korpanty G, Sullivan LA, Smyth E, Carney DN, Brekken RA: Molecular and clinical aspects of targeting the VEGF pathway in tumors. Journal of Oncology 2010:652320, 2010

Du L, Schageman JJ, Irnov, Girard L, Hammond SM, Minna JD, Gazdar AF, Pertsemlidis A:MicroRNA expression distinguishes SCLC from NSCLC lung tumor cells and suggests a possible pathological relationship between SCLCs and NSCLCs. Journal of Experimental and Clinical Cancer Research 29:75, 2010

Sullivan JP, Minna JD: Tumor oncogenotypes and lung cancer stem cell identity. Cell Stem Cell 7:2-4, 2010

Villasenor A, Wang ZV, Rivera LB, Ocal O, Asterholm IW, Scherer PE, Brekken RA, Cleaver O, Wilkie TM: Rgs16 and Rgs8 in embryonic endocrine pancreas and mouse models of diabetes. Disease Models and Mechanisms 3:567-80, 2010

Schwarz RE, Abou-Alfa GK, Geschwind JF, Krishnan S, Salem R, Venook AP: Nonoperative therapies for combined modality treatment of hepatocellular cancer: expert consensus statement. HPB (Oxford) 12:313-20, 2010

Dixon E, Abdalla E, Schwarz RE, Vauthey JN: AHPBA/SSO/SSAT sponsored Consensus Conference on Multidisciplinary Treatment&