Molecular Biophysics Faculty and Research
Program faculty have diverse backgrounds and interests, ranging from mathematics and theoretical physics to neurobiology and genetics.
Research in the Molecular Biophysics Graduate Program is highly interdisciplinary, comprising faculty drawn from the departments of Biophysics, Pharmacology, Physiology, Cell Biology, Neuroscience, Radiology, Obstetrics and Gynecology, and others. A list of faculty with their research interests is given below.
Mike Henne, Ph.D., Assistant Professor
Research Interests: Molecular Mechanisms of Membrane Sculpting; formation and dynamics of inter-organelle membrane contact sites (MCSs) in human health and disease
Khuloud Jaqaman, Ph.D., Assistant Professor
Research Interests: Quantitative single-molecule imaging of receptor organization and signaling; linking molecular and cellular behavior across multiple scales; computational image analysis and data multiplexing
Xin Liu, Ph.D., Assistant Professor
Research Interests: Roles of chromatin and nuclear organization in transcriptional regulation; structural and biochemical studies of chromatin dynamics during transcriptional activation and repression.
Craig R. Malloy, M.D., Professor
Research Interests: The analysis of metabolism in intact tissues by NMR spectroscopy; development of new methods to understand metabolic processes in functioning cells
Ralph P. Mason, Ph.D., Professor
Research Interests: Development of novel techniques for prognostic radiology with emphasis on tumor oxygenation, pH, and efficacy of gene therapy; nuclear magnetic resonance, bioluminescence, PET and SPECT
Michael Reese, Ph.D., Assistant Professor
Research Interests: Biochemistry; Biophysics; Cell signaling, kinases, pseudokinases; Host-pathogen interaction; co-evolution; Immunology; Structural biology
Luke Rice, Ph.D., Assistant Professor
Research Interests: Integrating structure, kinetics, and computation to understand the molecular determinants and regulatory mechanisms of microtubule dynamics
Elliott Ross, Ph.D., Professor
Research Interests: Mechanisms of G-protein signaling; amplification, selectivity, response timing; structure/function of GTPase-activating proteins and associated receptors
Guanghua (Andy) Xiao, Ph.D., Associate Professor
Research Interests: Statistical methods for genomics/proteomics and in spatial/image analysis
Yang Xie, Ph.D., Associate Professor
Research Interests: Processing and analysis of high throughput data; false discovery rate estimation; integrated analysis methodology; Bayesian analysis methodology; design and analysis of clinical trials
Xuewu Zhang, Ph.D., Associate Professor
Research Interests: Biochemical and Structural studies of regulation mechanisms for signaling proteins, especially receptor-mediated signaling pathways in neuron development and axonal guidance
These faculty members do not accept graduate students. They participate in teaching, co-mentoring, exam and dissertation committees, and all other program responsibilities.
Joseph Albanesi, Ph.D., Professor
Research Interests: Mechanisms of membrane fusion; role of lipids in membrane trafficking; membrane vesiculation of dynamin
Dominika Borek, Ph.D., Assistant Professor
Research Interests: Eukaryotic chromatin organization, mutational rates and spectra, biological signals and noise
Chad Brautigam, Ph.D., Associate Professor
Research Interests: Basic processes in living organisms at atomic level, using X-ray crystallography, analytical ultracentrifugation, isothermal titration calorimetry, and other biophysical techniques
Zhe Chen, Ph.D., Assistant Professor
Research Interests: Structural and functional studies of proteins in signal transduction
Jan Erzberger, Ph.D.
Research Interests: Structural and biochemical characterization of dynamic protein-RNA complexes during ribosome biogenesis
Milo Lin, Ph.D.
Research Interests: Theoretical and computational approaches to predict protein folding and aggregation; evolutionary dynamics
William Russ, Ph.D., Assistant Professor
Research Interests: Evolutionary principles of enzyme design
Diana R. Tomchick, Ph.D., Professor
Research Interests: Basic processes in living organisms at atomic level using X-ray crystallography, NMR spectroscopy, and other biophysical techniques