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Protein Kinase Cascades: From Fundamentals to Applications

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The Lab is Accepting Grad Students!

Several projects, including studies of salt sensing by WNK isoforms, and analysis of "two-way induced-fit" mechanisms in MAP kinase signaling and other signal transduction pathways have a clearly defined trajectory.

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"You can study anything, so it's best if the topic is interesting from multiple points of view."

- Dr. Elizabeth Goldsmith

"Structural and biophysical aspects of protein:protein and protein:drug interactions help in understanding mechanisms of signal transduction in MAP kinase and WNK pathways."

- Dr. Akella Radha

"We are developing targeted mass spectrometry techniques to study the kinetic and mechanism of phosphorylation in the MAPK and WNK1 kinase cascades."

- Dr. John Humphreys

"The task is … not so much to see what no one has yet seen; but to think what nobody has yet thought, about that which everybody sees."

- Erwin Schrödinger