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Structural mechanism

The structures of ion channels and transporters, and their interaction with the scaffolding proteins, are investigated using cryo-EM microscopy methods

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Quantitative Electrophysiology

Quantification of the activation of ion channels/transporters under different physical and biochemical conditions

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Ion channel and membrane receptor clusters

Some ion channels and membrane receptors (green) are clustered by scaffolding proteins (red) in cells

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In-Solution TIRFM

Development of an instrument for simultaneous electrophysiology and fluorescence microscopy with a novel TIRFM technology

About Us

We study ion channel clusters. To study such clusters without the complications arising from the complex cellular environment, components from cells are purified and studied in isolation.