Immunology Faculty

Kiyoshi Ariizumi
Associate Professor
Research Interests: Molecular mechanisms for the pathogenesis of skin diseases.

Michael Bennett, MD
Professor
Research Interests: Immunogenetics and immunobiology of marrow-cell grafts; differentiation and function of NK cells; graft-versus-host reactions; natural immunity to infection; tumor immunology

Zhijian (James) Chen, PhD
Professor
Research Interests: Ubiquitin-proteasome pathway; NF-kappaß signaling; innate immunity; T cell receptor signaling

Peter Chen, PhD
Assistant Professor
Research Interests: Epigenetic gene regulation in an immune privileged environment; ocular
immunology; tumor immunosurveillance

Laurie S. Davis, PhD
Associate Professor
Research Interests: T-cell activation; autoimmunity; cytokine regulation

Todd Eagar, PhD
Assistant Professor
Research Interests: Regulation of T cell activation and differentiation, therapeutic control of autoimmune disease

Pila Estess, PhD
Assistant Professor
Research Interests: Molecular immunology; structure/function relationships in lymphocyte cell-surface antigens, including CD44 and lymphocyte homing receptors; role of these molecules in autoimmune diseases and inflammation; molecular pathology

J. David Farrar, PhD
Associate Professor
Research Interests: Molecular immunology; signal transduction; regulation of T-cell differentiation and cytokine gene expression

James Forman, PhD, DMD
Professor
Research Interests: T-cell recognition of major histocompatibility complex molecules; nonclassical class I molecules; NK cells

Michelle Joubert Gill, MD, PhD
Assistant Professor
Research Interests: Pathogenesis and immunobiology of infectious disease; human dendritic cells in respiratory syncytial viral infections; the host mucosal immune response to respiratory viral infections in children; dendritic cells in the pathogenesis of asthma

William T. Garrard, PhD
Professor
Research Interests: Regulation of V(D)J recombination of antibody genes; chromosome structure; control of gene expression; chromosome replication, condensation and segregation at mitosis; nuclear organization

Rebecca S. Gruchalla, MD, PhD
Professor
Research Interests: Immunopathology of antibiotic drug allergy, specifically sulfonamide drug allergy

Eric J. Hansen, PhD
Professor
Research Interests: Microbial pathogenesis and the immune response; use of recombinant DNA methods in vaccine development

Lora Hooper, PhD
Associate Professor
Research Interests: Host-microbial interactions; mucosal immunology

Nitin J. Karandikar, MD, PhD
Professor
Research Interests: The role of CD4 and CD8 T cells in the pathogenesis and regulation of multiple sclerosis; mechanisms of therapeutic immunomodulation of MS; B7/CD28:CTLA-4-mediated costimulation in autoimmune demyelination; molecular characterization of T cells mediating GVH versus GVL effects in patients with leukemia; effector CTL responses in viral infections

David R. Karp, MD, PhD
Professor
Research Interests: Function of class II molecules of the major histocompatibility complex, including antigen presentation and its role in autoimmune disease; role of complement receptors in B-cell activation and presentation of soluble antigens

Christopher Y. H. Lu, MD
Professor
Research Interests: Transplant tolerance; regulation of macrophage function; ontogeny of macrophage function and its implications for self/nonself discrimination and autoimmunity; mechanisms of renal allograft rejection

Bonnie Miller, PhD
Assistant Professor
Research Interests: Mechanisms of opioid immunomodulatory effects

Chandra Mohan, MD, PhD
Professor
Research Interests: The immunopathology and immunogenetics of lupus; immunological tolerance; autoimmunity

Nancy Monson, PhD
Associate Professor
Research Interests: The role of B cells in the pathogenesis of multiple sclerosis

Jerry Y. Niederkorn, PhD
Professor
Research Interests: Immune privilege of the anterior chamber of the eye; immune surveillance of intraocular tumors; immune modulation of cancer metastases; immunobiology of corneal transplants; immunology of parasitic diseases

Chandrashekhar Pasare, PhD
Assistant Professor
Research Interests: Toll-like receptors and control of adaptive immunity: dendritic cell biology

Anne B. Satterthwaite, PhD
Associate Professor
Research Interests: Genetic analysis of signal-transduction pathways regulating B lymphocyte development and function

John Schatzle
Research Interests: Natural killer cell receptor structure and function; molecular mechanisms of bone-marrow transplant rejection and tumor lysis by NK cells

Richard H. Scheuermann, PhD
Professor
Research Interests: Regulation of immunoglobulin gene expression; regulation of lymphocyte growth, development and apoptosis; lymphocyte receptor signal transduction; technology development; novel approaches to cancer therapy

Mark H. Siegelman, MD, PhD
Associate Professor
Research Interests: The molecular biology of cell-surface molecules governing adhesion to and transmigration through vascular endothelium

Olaf Stuve, MD, PhD
Associate Professor
Research Interests: Prion protein (PrP) as a disease modifier in autoimmune diseases of the central nervous system

Nancy E. Street, PhD
Associate Dean, Graduate School of Biomedical Sciences
Research Interests: Activation and differentiation of murine T-helper cells; the role of T-helper cells in tumor dormancy and infectious disease

Iwona Stroynowski, PhD
Professor
Research Interests: Structure and function of immunologically relevant molecules; antigen presentation in the immune system

Joel D. Taurog, MD
Professor
Research Interests: Biology of HLA and disease

Dwain L. Thiele
Professor
Research Interests: Mechanisms of cytotoxic lymphocyte function and activation; transplantation immunology

James A. Thomas, MD
Associate Professor
Research Interests: Signal transduction in innate immunity

Jonathan W. Uhr, MD
Professor
Research Interests: Cancer immunology and genetics

Nicolai S. C. van Oers, PhD
Associate Professor
Research Interests: Regulation of antigen-receptor signal-transduction systems

Ellen S. Vitetta, MD, PhD
Professor
Research Interests: The development, genetic engineering, and testing of immunotoxins, antibodies, and vaccines in animals and humans; the immunology of tumor dormancy; Gulf War Syndrome; multidrug resistance in tumors

Edward K. (Ward) Wakeland, PhD
Professor
Research Interests: The molecular biology of genes regulating immune responses and autoimmunity

E. Sally Ward, PhD
Professor
Research Interests: Genetic manipulation and structure/function studies of antibodies and T-cell receptors; T-cell mediated autoimmunity

Jonathan C. Weissler, MD
Professor
Research Interests: Regulation of cytotoxic lymphocytes in human lung; accessory cell function in human lung

Christoph Wuelfing, PhD
Associate Professor
Research Interests: T-cell activation using video microscopy; costimulation and cell biology of T-cell activation

Felix Yarovinsky, MD
Assistant Professor
Research Interests: Toll-like receptor signaling, dendritic cells, and host-pathogen interactions

Dorothy C. Yuan, PhD
Professor
Research Interests: Molecular regulation of immunoglobulin synthesis; interactions between B and T lymphocytes and NK cell

Chengcheng (Alec) Zhang, PhD
Assistant Professor
Research Interests: Mechanisms by which the cell fates of adult stem cells are regulated, and the interaction of adult stem cells and their in vivo microenvironment; ex vivo expansion of HSCs for cell therapy and gene therapy; the interplay between stem cells and cancer