We are identifying and characterizing the downstream antiviral effector mechanisms of type I interferon.
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High-throughput cell-based screens
We use high-throughput, FACS-based techniques to evaluate the antiviral potential of hundreds of interferon-stimulated genes on a diverse panel of viruses.
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Dengue reporter viruses
We have developed dengue viruses that express fluorescent and luminescent reporters for studying pathogen-host interactions in vitro and in vivo.