Human Research Protection Program Office (HRPPO)/Institutional Review Board (IRB)

About the HRPPO/IRB

The UT Southwestern Medical Center Human Research Protection Program is responsible for ensuring that all human-subject research conducted by faculty, staff, or students for UTSW is conducted ethically and in compliance with federal regulations and policies that promote ethical research in human subjects.

The HRPPO is a division under Research Administration and incorporates three primary functions to achieve its objectives: research review, education, and quality assurance.

Research Review

All human-subject research conducted by UT Southwestern faculty, staff, or students on behalf of UT Southwestern must be reviewed by the HRPPO. Within the HRPPO, there are two routes of review:

  • IRB Review – Research reviewed by one of four UT Southwestern IRBs or by an Expedited Reviewer
  • Reliance Review – Research reviewed by a non-UT Southwestern IRB will undergo an abbreviated review

In accordance with the Federalwide Assurance (FWA) on file with the U.S. Department of Health and Human Services, the UTSW IRB reviews and approves research involving human subjects that is conducted at: Children’s Healthâ„ , Parkland Health & Hospital System, Texas Scottish Rite Hospital for Children, UTSW, and The Retina Foundation of the Southwest.

The IRB must also review and approve all research supported by grants and contracts involving human subjects conducted at Texas Health Presbyterian Dallas and the Dallas Veterans Affairs Medical Center, in which a UTSW faculty member serves as principal investigator.

Education

The HRPPO offers both required and optional training opportunities in a multitude of formats. Required ethics education training is offered online by CITI, while numerous face-to-face educational classes are scheduled each month for research teams in collaboration with the Center for Translational Medicine (CTM). In addition, the HRPPO offers monthly educational forums intended to bring the research community together around numerous ethical and regulatory issues.

Quality Assurance

The HRPPO Quality Assurance (QA) Program supports research that is subject to the authority of the UTSW IRB in accordance with applicable IRB requirements; institutional policies and procedures; and federal, state, and local regulations.

The HRPPO QA Program works closely with the Education, Compliance, and Privacy Programs at UTSW and its Affiliates to identify educational opportunities, implement best practices, and institute systemic improvement.