Our faculty performs cutting-edge clinical, translational, and basic science research in the pathogenesis and treatment of infectious diseases, including HIV, CNS viral infections, hepatitis C virus, respiratory tract infections, and gram-negative bacterial infections.
Basic Science Research Highlights
- Pharmacology of antituberculosis and other antimycobacterial agents
- Shortening antituberculosis and anti-MAC therapy Clinical Trial simulations using
- Monte Carlo methods Antimicrobial pharmacokinetic-pharmacodynamics and pharmacogenetics
- Application of pharmacogenetic based dosing to Global Health Problems
- Autophagy and infection
- Autophagy and cancer biology
- Autophagy and cell death regulation
Defining the prevalence of infection due to Trypanosoma cruzi (Chagas Disease) in the human population of the Toledo District of Belize.
Clinical Research Highlights
- Novel therapies for patients with drug-resistant HIV
- Studies of lipid risk factors, prevention and management of hyslipidemia, lipodystrophy and bone mineral loss among HIV-infected patients
- Studies of simplified combination therapy and novel immune-based therapy
- Laboratory-based research to understand the mechanisms of dyslipidemia among HIV and HIV/HCV co-infected patients
Viral Kinetics: Examining the change in HCV viral load after pegylated interferon and ribavirin initiation.
HIV/HCV Observational Study: Following HIV/HCV co-infected patients over time to examine outcomes such as mortality and development of end-stage liver disease.