MSTP Alumni 2000-2013

Class of 2000 Class of 2001 Class of 2002
Class of 2003 Class of 2004 Class of 2005
Class of 2006 Class of 2007 Class of 2008
Class of 2009 Class of 2010 Class of 2011
Class of 2012 Class of 2013 Class of 2014

Class of 2014

Stan Atkin
Dissertation Topic: Liver Receptor Homolog-1 Regulates Kisspeptin Expression in the Arcuate Nucleus to Promote Reproductive Axis Function
Mentors: David Mangelsdorf, Ph.D. and Steven Kliewer, Ph.D.
Current Position: Resident, Internal Medicine
Current Affiliation: UT Southwestern Medical Center

Jenny Barker
Dissertation Topic: Site-Specific Genome Engineering in Mouse Primary Fibroblasts
Mentor: Matthew Porteus, Ph.D., Stanford Medical School
Current Position: Resident, Plastic Surgery (Integrated)
Current Affiliation: Ohio State University School of Medicine

M. Edward Haws
Research Interest: Effects of Regional Deletion of Rab3A-interacting Molecule and PTEN on Brain Function
Mentor: Craig Powell, M.D., Ph.D.
Current Position: Resident, Pediatric Neurology
Current Affiliation: Cincinnati Children's Hospital - University of Cincinnati College of Medicine

Imran Mohiuddin
Dissertation Topic: Preferential Regulatory T-cell Generation From Memory CD4 T-Cells is Deficient During Acute Exacerbation of Multiple Sclerosis
Mentor: Nitin Karandikar, M.D., Ph.D., University of Iowa
Current Position: Resident, Radiation Oncology
Current Affiliation: University of Iowa Hospitals & Clinics

Daniel Quiat
Dissertation Topic: Transcriptional Regulation of Muscle Contractility and Metabolism by a MicroRNA-Mediated Feed Forward Loop
Mentor: Eric Olson, Ph.D.
Current Position: Resident, Pediatrics
Current Affiliation: Harvard University – Children’s Hospital, Boston

Oktay Rifki
Dissertation Topic: RalGDS-Dependent Cardiomyocyte Autophagy is Necessary for Load-Induced Ventricular Hypertrophy
Mentor: Joseph Hill, M.D., Ph.D.
Current Position: Resident, Internal Medicine
Current Affiliation: New York Presbyterian Hospital/Weill Cornell Medical Center

Swalpa Udit
Dissertation Topic: NAV1.8+ Visceral Afferent Neurons:  Roles in Metabolism & Inflammation
Mentor: Joel Elmquist, D.V.M, Ph.D.
Current Position: Resident, Internal Medicine
Current Affiliation: University of California at San Francisco Medical Center

Richard Voit
Dissertation Topic: Generation of HIV-Resistant T-cells & Correction of the Sickle Cell Mutation by Targeted Genome Engineering
Mentor: Matthew Porteus, M.D., Ph.D., Stanford University
Current Position: Resident, Pediatrics
Current Affiliation: Harvard University – Children’s Hospital, Boston

Koriand’r Williams
Dissertation Topic: Antagonistic Roles of MIR-199A-3P/MIR-214 and the MIR-200 Family in the Regulation of Uterine Contractility during Pregnancy and Labor
Mentor: Carole Mendelson, Ph.D.
Current Position: Resident, Physical Medicine & Rehabilitation
Current Affiliation: University of Arkansas School of Medicine, Little Rock

Dongbo Yu
Dissertation Topic: Using Chemically Modified Oligonucleotides to Modulate Gene Expression, Treat Genetic Diseases, and Probe Novel Mechanisms of RNA Interference
Mentor: David Corey, Ph.D.
Current Position: Resident, Internal Medicine
Current Affiliation: University of Chicago Medical Center

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Class of 2013

Ethan Baughman
Thesis Title: Neuroantigen-Specific CD8+Regulatory T-Cell Function is Deficient during Acute Exacerbation of Multiple Sclerosis
Mentor: Nitin Karandikar, M.D., Ph.D.
Current Position: Resident, Plastic Surgery
Current Affiliation: Washington University School of Medicine/Barnes – Jewish Hospital

Robert Li
Thesis Title: Essential Function of Ghrelin in Chronic Starvation
Mentors: Michael Brown, M.D. and Joseph Goldstein, M.D.
Current Position: Resident, Internal Medicine/PSTP
Current Affiliation: Northwestern University

Anna Patrick
Thesis Title: Co-translational Folding of CFTR
Mentor: Philip Thomas, Ph.D.
Current Position: Resident, Pediatrics
Current Affiliation: Vanderbilt School of Medicine

David Patrick
Thesis Title: Regulation of Cellular Growth and Differentiation by microRNAs-21 and -451
Mentor: Eric Olson, Ph.D.
Current Position: Resident, Internal Medicine
Current Affiliation: Vanderbilt School of Medicine

Brian Skaug
Thesis Title: Mechanisms Governing NF-KappaB Regulation by the Anti-Inflammatory Protein A20
Mentor: Zhijian Chen, Ph.D.
Current Position: Resident, Internal Medicine
Current Affiliation: UT Southwestern Medical Center

Christopher Smith
Thesis Title: Regulation of Cardiac Fibroblast and Coronary Vascular Smooth Muscle Development by Platelet Derived Growth Factor Receptors
Mentor: Michelle Tallquist, Ph.D.
Current Position: Resident, Pediatrics
Current Affiliation: Children’s Hospital, Philadelphia, PA

Jamie Walker
Thesis Title: NPAS1 and its Relation to Autism
Mentor: Steve McKnight, Ph.D.
Current Position: Resident, Pathology
Current Affiliation: University of Texas Southwestern Medical Center, Dallas, TX

Michael Wang
Thesis Title: The Hydrophobic Handoff of Cholesterol between NPC2 and the N-terminal Domain of NPC1in the Export of Cholesterol from Lysosomes
Mentors: Michael Brown, M.D. and Joseph Goldstein, M.D.
Current Position: Resident, Pathology
Current Affiliation: University of Michigan Hospitals, Ann Arbor, MI

Daniel Zeve
Thesis Title: Improved Glucose Homeostasis in a Metabolic Paradox
Mentor: Jon Graff, M.D., Ph.D.
Current Position: Resident, Pediatrics
Current Affiliation: Mount Sanai, Icahn School of Medicine

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Class of 2012

Mark Etherton
Dissertation Topic: Molecular Pathogenesis of Autism: A Role for Neurexin & Neuroligin
Mentor: Thomas Südhof, M.D. (Stanford University)
Current Position: Clinical Fellow, Neurology
Current Affiliation: Harvard University – Massachusetts General Hospital

Bret Evers
Dissertation Topic: Role of Insig-Mediated Cholesterol Homeostasis in the Development of the Palate & Hair Follicles in Mice
Mentors: Michael Brown, M.D., and Joseph Goldstein, M.D.
Current Position: Clinical Postdoctoral Trainee, Pathology
Current Affiliation: University of Texas Southwestern Medical Center, Dallas, TX

Midhat Farooqi
Dissertation Topic: The Role of Insig-Mediated Cholesterol Homeostasis in Mouse Hair Development
Mentors:  Michael Brown, M.D., and Joseph Goldstein, M.D.
Current Position: Clinical Postdoctoral Trainee, Pathology 
Current Affiliation: University of Texas Southwestern Medical Center, Dallas, TX

Rodney Infante
Dissertation Topic: Unraveling Niemann-Pick: A Disease of Cholesterol Transport
Mentors:  Michael Brown, M.D., and Joseph Goldstein, M.D.
Current Position: Clinical Fellow, Internal Medicine
Current Affiliation: Harvard/Massachusetts General Hospital

David Meredith
Dissertation Topic: Comparative Analysis of Developmental Programs Controlled by Ptfl a
Mentor: Jane Johnson, Ph.D.
Current Position: Clinical Fellow, Pathology
Current Affiliation: Harvard University – Brigham & Women’s Hospital

Anthony Orvedahl
Dissertation Topic: Autophagy in Antiviral Immunity
Mentor: Beth Levine, M.D.
Current Position: Resident, Pediatrics
Current Affiliation: Washington University School of Medicine – St. Louis Children’s Hospital

Vera Paulson
Dissertation Topic: High-Resolution Array Comparative Genomic Hybridization Reveals Targets in Rhabdomyosarcoma
Mentor: Scott Cameron, M.D., Ph.D. (Novartis Institutes for Biological Research, Cambridge, Mass.)
Current Position: Clinical Fellow, Pathology
Current Affiliation: Harvard University – Brigham & Women’s Hospital

Alan Poole
Dissertation Topic: Collective Structural Modes in Proteins: A Case Study in the PDZ Domain
Mentor: Rama Ranganathan, M.D., Ph.D.
Current Position: Resident, Pediatrics
Current Affiliation: UT Southwestern

Nora Renthal
Dissertation Topic: The miR-200 Family and Targets, ZEB1 and ZEB2, Modulate Uterine Quiescence and Contractility during Pregnancy and Labor
Mentor
: Carole Mendelson, Ph.D.
Current Position: Resident, Pediatrics
Current Affiliation: University of Texas Southwestern Medical Center, Dallas, TX

Daniel Schmidt
Dissertation Topic: Bile Acids and Nuclear Receptors: Their Roles in Nutrition and Cancer
MentorDavid Mangelsdorf, Ph.D.
Current Position: Clinical Fellow, Radiation Oncology
Current Affiliation: Harvard University – Brigham & Women’s Hospital

Jason Tuckerman
Dissertation Topic: Heme-based Oxygen Sensors in Commensal and Pathogenic Bacteria
Mentor:  Marie-Alda Gilles-Gonzalez, Ph.D.
Current Position: Resident, Internal Medicine Research Pathway
Current Affiliation: Case Western Reserve University School of Medicine

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Class of 2011

John Astle
Dissertation Topic: Rapid Identification of Antigen Mimics from Millions of Synthetic Molecules through Coupled Bead Library Screening & Microarray Analysis
Mentor: Thomas Kodadek, Ph.D. (Scripps Research Institute)
Current Position: Resident, Pathology
Current Affiliation: Yale University School of Medicine

Abigail Nash
Dissertation Topic: Structural Basis for Signal Transduction in LOV Blue Light Photoreceptors
Mentor: Kevin Gardner, Ph.D.
Current Position: Resident, Psychiatry
Current Affiliation: Emory University School of Medicine

David Owen
Dissertation Topic: Hepatitis C Virus Entry into Hepatocytes and Engagement of Innate Immune Defenses
Mentor: Michael Gale, Ph.D. (University of Washington)
Current Position: Resident, Ob/Gyn
Current Affiliation: University of Texas Southwestern Medical Center, Dallas, TX

William Renthal
Dissertation Topic: Epigenetic Mechanisms in Drug Addiction
Mentor: Eric Nestler, M.D., Ph.D. (Mount Sinai School of Medicine)
Current Position: Resident, Neurology
Current Affiliation: University of Texas Southwestern Medical Center, Dallas, TX

Ameen Salahudeen
Dissertation Topic: FBXL5: Sensor & Regulator of Mammalian Iron Homeostasis
Mentor: Rick Bruick, Ph.D.
Current Position: Fellow, Hematology/Oncology 
Current Affiliation: Stanford Hospital and Clinics, Stanford, CA

Andrew Wang
Dissertation Topic: The Roles of Ly108, the Genetic Susceptibility Loci Sle3, and CXCR4/CXCL12 in Systemic Lupus Erythematosus
Mentor: Ward Wakeland, Ph.D.
Current Position: Clinical Fellow, Internal Medicine/Rheumatology
Current Affiliation: Yale University School of Medicine

Rebekkah Warren
Dissertation Topic: Genetic Reduction of Cholesterol Synthesis in the Mouse Brain does not affect Amyloid Formation in an Alzheimer’s Disease Model, but does Expand Lifespan
Mentor: David Russell, Ph.D.
Current Position: Resident, Surgery
Current Affiliation: Mayo Clinic, Rochester, MN

Kyle Wedin
Dissertation Topic: With No Lysine (WNK) Family Proteins and their Interactions with Downstream Kinases
Mentor: Melanie Cobb, Ph.D.
Current Position: Resident, Internal Medicine
Current Affiliation: Emory University School of Medicine, Atlanta, GA

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Class of 2010

David Benavides
Dissertation Topic: The Role of Cdk5 in the Regulation of Dopamine Neurotransmission, Neuronal Excitability, and Reward-Related Behavior
Mentor: James Bibb, Ph.D.
Current Position: Chief Resident, Neurology
Current Affiliation: Johns Hopkins University School of Medicine

Elizabeth Keohane-Bhoj
Dissertation Topic: Using Balance Translocation to Discover Novel Disease Causing Genes: Potential Involvement of Basonuclin 2 in Congenital Heart Disease and Palmitoylated Membrane Protein 7 in Mature-Onset Diabetes of the Young
Mentor: Andrew Zinn, Ph.D.
Current Position: PGY3 Resident, Pediatrics (Pediatric Genetics)
Current Affiliation: Children’s Hospital of Philadelphia

Vijay Bhoj
Dissertation Topic: Innate and Adaptive Immune Responses to Respiratory Syncytial Virus
Mentor: Zhijian (James) Chen, Ph.D.
Current Position: Resident, Pathology
Current Affiliation: Hospital of the University of Pennsylvania

Vaishnav “Kris” Krishnan
Dissertation Topic: Vulnerability and Resilience to Social Defeat: The Role of Neuroplasticity within the Mesolimbic Dopamine Circuit
Mentor: Eric Nestler, M.D., Ph.D. (Mount Sinai School of Medicine)
Current Position: Clinical Fellow, Adult Neurology
Current Affiliation: Harvard-Beth Israel Deaconess Medical Center (Adult Neurology)

James Lee
Dissertation Topic: Structural Insights into Bacterial Sporulation
Mentor: Kevin Gardner, Ph.D.
Current Position: Resident, Pathology
Current Affiliation: Harbor-UCLA Medical Center

Markey McNutt
Dissertation Topic: Characterization of the Non-Proteolytic Mechanism and Cellular Site of Action of PCSK9 Mediated Degradation of the Low-Density Lipoprotein Receptor
Mentor: Jay Horton, M.D.
Current Position: Postdoctoral Fellow, Internal Medicine/Endocrinology
Current Affiliation: University of Texas Southwestern Medical Center, Dallas, TX

Joseph Park
Dissertation Topic: Characterization of Factors Controlling Germline Stem Cell Maintenance in Drosophila melanogaster
Mentor: Dennis McKearin, Ph.D. (HHMI)
Current Position: Fellow, Pediatric Hematology/Oncology
Current Affiliation: Stanford University

Maggie Waung
Dissertation Topic: Rapid Protein Translation Governs Persistent Changes in Ampar Trafficking in a Form of Long-Term Synaptic Plasticity
Mentor: Kimberly Huber, Ph.D.
Current Position: Resident, Adult Neurology
Current Affiliation: University of California at San Francisco Medical Center

Nathan York
Dissertation Topic: CNS-specific, Autoreactive CD8+ T-cells have a Regulatory Role in Autoimmune Demyelination
Mentor: Nitin Karandikar, M.D., Ph.D.
Current Position: Pediatrician
Current Affiliation: Sunshine Valley Pediatrics, Las Vegas, NV

Bryan Young
Dissertation Topic: Histone Deacetylase 7 in Cardiovascular Development and Transcriptional Regulatory Networks of the Vascular Endothelium
Mentor: Eric Olson, Ph.D.
Current Position: Clinical Fellow, Internal Medicine/ Cardiology
Current Affiliation: Yale University Medical Center

Melissa Rasar Young
Dissertation Topic: Paxillin is a Novel Regulator of Xenopus Oocyte Maturation
Mentor: Stephen Hammes, Ph.D. (University of Rochester Medical Center)
Current Position: PGY4 Resident, Therapeutic Radiology/Radiation Oncology
Current Affiliation: Yale University Medical Center

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Class of 2009

Christian Gocke
Dissertation Topic: Regulation of Chromatin-Associated Proteins by Sumoylation
Mentor: Hongtao Yu, Ph.D.
Current Position: Fellow, Medicine, Hematology/Oncology
Current Affiliation: Johns Hopkins University

Ammar Hawasli
Dissertation Topic: Regulation of Excitatory Neurotransmission, Synaptic Plasticity, and Learning by Cyclin-Dependent Kinase 5
Mentor: James Bibb, Ph.D.
Current Position: Clinical Fellow, Neurosurgery
Current Affiliation: Washington University/Barnes-Jewish Hospital (St. Louis, MO)

Cindy Johnson
Dissertation Topic: Hepatitis C Virus NS3/4A Protease and the Intracellular Antiviral Response: Mapping Complex Virus-Host Interactions
Mentor: Michael Gale, Ph.D. (University of Washington)
Current Position: Clinical Fellow, Medicine, Infectious Diseases
Current Affiliation: Washington University/Barnes-Jewish Hospital (St. Louis, MO)

Brian Keller
Dissertation Topic: Insights into Virus-host Interactions: Regulation of Cytokine Signaling is a Virulence Determinant of West Nile Virus
Mentor: Michael Gale, Ph.D. (University of Washington)
Current Position: Clinical Fellow, Medicine, Pulmonary/Critical Care
Current Affiliation: Washington University/Barnes-Jewish Hospital (St. Louis, MO)

Christopher Larson
Dissertation Topic: Evolutionary Constraints Specifying Protein Folding and Function
Mentor: Rama Ranganathan, M.D., Ph.D.
Current Position: Postdoctoral Fellow, Tony Reid Lab
Current Affiliation: UC San Diego Medical Center

Amy Mellgren Archer
Dissertation Topic: PDGFR beta Signaling in Mouse Epicardial and Mural Cells Influences Blood Vessel Remodeling
Mentor: Michelle Tallquist-Seidel, Ph.D.
Current Position: Fellow, Rheumatology (2012-13 Driskill Fellow)
Current Affiliation: Northwestern University Feinberg School of Medicine, Chicago, IL

Alexis Melton
Dissertation Topic: Combinatorial Control of CD45 Signal-Induced Exon Repression by hnRNP L and PSF
Mentor: Kristen Lynch, Ph.D. (University of Pennsylvania)
Current Position: Clinical Fellow, Pediatric Hematology/Oncology
Current Affiliation: University of California at San Francisco Medical Center

Prashant Mishra
Dissertation Topic: Dynamic Scaffolding in a G-Protein Signaling Cascade
Mentor: Rama Ranganathan, M.D., Ph.D.
Current Position: Postdoctoral Scholar, Biology & Biological Engineering
Current Affiliation: California Institute of Technology – Laboratory of David Chan, M.D., Ph.D. (HHMI/Department of Biology)

Baochan Nguyen
Dissertation Topic: Protein Phosphatase Inhibitor-1 and CDK5: Of Molecules and Memory
Mentor: James Bibb, Ph.D.
Current Position: Assistant Professor, Ophthalmology
Current Affiliation: University of Texas Southwestern Medical Center, Dallas, TX

Brent Presley
Dissertation Topic: Novel Roles of Gastrin and Cholescystokinin in Islet Beta Cell Proliferation
Mentor: Christopher Newgard, Ph.D. (Duke)
Current Position: Clinical Postdoctoral Trainee, Pediatrics
Current Affiliation: University of Texas Southwestern Medical Center, Dallas, TX 

Paul Tannous
Dissertation Topic: Cardiomyocyte Autophagy is Induced by Protein Aggregation in Heart Disease
Mentor: Joseph Hill, M.D., Ph.D.
Current Position: Clinical Fellow, Pediatric Cardiology
Current Affiliation: Harvard University – Children’s Hospital of Boston

Mark Valasek
Dissertation Topic: The Regulation of Cholesterol Absorption: Nuclear Hormone Receptors and Niemann-Pick C1 Like 1
Mentor: Joyce Repa, Ph.D.
Current Position: Assistant Professor, Pathology
Current Affiliation: UC San Diego Medical Center

Jadon Webb
Dissertation Topic: Slow Inactivation of Sodium Channels: Structural Clues
Mentor: Stephen Cannon, M.D., Ph.D.
Current Position: Clinical Fellow, Psychiatry, Child Study Center
Current Affiliation: Yale University Medical Center

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Class of 2008

Michael Arnold
Dissertation Topic: The MEF2 Transcription Factor is an Essential Regulator of Bone Development
Mentor: Eric Olson, Ph.D.
Current Position: Faculty, Pediatric Pathology
Current Affiliation: Nationwide Children’s Hospital, Ohio State University, Wexner Medical Center, Columbus OH

Tracy Clyne Beswick
Dissertation Topic: Allosteric Regulation of S-Adenosylmethionine Decarboxylase from T. Cruzi
Mentor:
Meg Phillips, Ph.D.
Current Position: Dermatologist
Current Affiliation: Private Practice, Tulsa, OK

Nathan Bingham
Dissertation Topic: Loss of Ventromedial Hypothalamic Leptin Receptors Results in Increased Adiposity and a Metabolic Syndrome
Mentor: Keith Parker, M.D. (deceased)
Current Position: Assistant Professor, Pediatric Endocrinology
Current Affiliation: Cincinnati Children's Hospital - University of Cincinnati College of Medicine

Alice Chan
Dissertation Topic: In vivo identification of Sle1b: Ly108 mediates autoantibody production
Mentor: Ward Wakeland, Ph.D.
Current Position: Clinical Fellow, Pediatric Rheumatology & Allergy/Immunology
Current Affiliation: University of California at San Francisco Medical Center

Temekka Leday
Dissertation Topic: Use of an Animal Model of Group A Streptococcal Infection to Identify Factors Important for Virulence
Mentor: Kevin McIver, Ph.D. (University of Maryland)
Current Position: Pathologist
Current Affiliation: Private Practice, Lewisville, TX

Daniel Motola
Dissertation Topic: Identification of Ligands for the Orphan Nuclear Receptor DAF-12 that Govern Dauer Formation and Reproduction in C. elegans
Mentor: David Mangelsdorf, Ph.D.
Current Position: Research Fellow, Medicine
Current Affiliation: Harvard University - Massachusetts General Hospital

Bogachan Sahin
Dissertation Topic: Evaluation and Characterization of Novel Signal Transduction Pathways in the Striatum
Mentor: James Bibb, Ph.D.
Current Position: Fellow, Vacular Neurology
Current Affiliation: Johns Hopkins University School of Medicine

Nadia Tsankova
Dissertation Topic: The Role of Chromatin Remodeling in Hippocampus in Depression and Antidepressant Action
Mentor: Eric Nestler, M.D., Ph.D. (Mount Sinai School of Medicine)
Current Position: Assistant Professor, Pathology & Cell Biology
Current Affiliation: Columbia University Medical Center, New York, NY

Brant Ward
Dissertation Topic: Behavioral characteristics of Langerhans cells in vivo.
Mentor: Akira Takashima, M.D., Ph.D. (University of Toledo)
Current Position: Instructor, Internal Medicine, Allergy & Immunology
Current Affiliation: MCVH-Virginia Commonwealth University

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Class of 2007

James Battiste
Dissertation Topic: Mash1 Defines Lineage-Restricted Neuron and Oligodendrocyte Precursor Cells in Spinal Cord Development
Mentor: Jane Johnson, Ph.D.
Current Position: Neurologist, Peggy & Charles Stephenson Cancer Center
Current Affiliation: University of Oklahoma Medical Center, Oklahoma City, OK

Jing-Tzyh (Alan) Chiang
Dissertation Topic: Evolution of Pharyngeal Feeding Behaviors in Free-living Soil Nematodes
Mentor: Leon Avery, Ph.D. (Virgina Commonwealth University)
Current Position: PGY4 Resident, Radiology
Current Affiliation: University of California at San Diego Medical Center

Luke Engelking
Dissertation Topic: Insig-Mediated Regulation of Hepatic Lipid Synthesis
Mentor: Mike Brown, M.D. and Joe Goldstein, M.D.
Current Position: Postdoctoral Trainee, Internal Medicine, Digestive & Liver Diseases
Current Affiliation: University of Texas Southwestern Medical Center, Dallas, TX

Jamison Feramisco
Dissertation Topic: SCAP, INSIG, and Cholesterol Interactions in Mammalian Cells
Mentor: Mike Brown, M.D. and Joe Goldstein, M.D.
Current Position: Chief Scientific Officer (MEDgle), Physician-in-Chief (Scanadu), President & Chief Medical Office (Golden Healthcare) 
Current Affiliation: MEDgle, San Mateo, CA; Scanadu (NASA) Moffett Field, CA; Golden Healthcare, Temecula, CA

Eileen Foy
Dissertation Topic: Control of Innate Antiviral Defenses by the Hepatitis C Virus NS3/4A Protease
Mentor: Michael Gale, Ph.D. (University of Washington)
Current Position: Clinical Fellow, Pediatrics, Infectious Disease
Current Affiliation: University of California at San Francisco Medical Center

Garrett Gotway
Dissertation Topic: The Role of Apobec2 in Striated Muscle Development and Function
Mentor: Deepak Srivastava, M.D. (UCSF)
Current Position: Assistant Professor, Pediatrics
Current Affiliation: University of Texas Southwestern Medical Center, Dallas, TX

Nathan Holladay
Dissertation Topic: Data-optimized Linear Predictors of Disorder in Proteins Yield Insight into Disorder Prediction and Physical Processes Underlying Disorder
Mentor: Nick Grishin, Ph.D.
Current Position: Clinical Assistant Professor, General Internal Medicine (last known position)
Current Affiliation: East Carolina University, Brody SOM, Greenville, NC

Christopher Jones
Dissertation Topic: Development and Analysis of an Animal Model of Autosomal Recessive Hypercholesterolemia
Mentor: Joachim Herz, M.D. and Helen Hobbs, M.D.
Current Position: Staff Physician, Internal Medicine
Current Affiliation: Platte Valley Medical Center, Brighton, CO<

Jason Mock
Dissertation Topic: The LspA Proteins of Haemophilus ducreyi: Extracellular Virulence Factors
Mentor: Eric Hansen, Ph.D.
Current Position: Clinical Fellow, Internal Medicine, Pulmonology/Respiratory
Current Affiliation: Johns Hopkins University School of Medicine

Charles Nguyen
Dissertation Topic: Haplotype-specific Effects of the SLAM/CD2 Family on the Immune Response
Mentor: Ward Wakeland, Ph.D.
Current Position: Hospitalist/Internist, Internal Medicine
Current Affiliation: Houston Northwest Medical Center/UT Health Science Center, Houston

Tim Rand
Dissertation Topic: A Biochemical Model for siRNA Loading and RISC activation in RNA interference
Mentor: Xiaodong Wang, Ph.D. (National Institute of Biological Sciences, Beijing)
Current Position: Staff Scientist, Dr. Shinya Yamanaka Lab
Current Affiliation: Gladstone Institutes/UCSF

Abhi Seth
Dissertation Topic: Autoinhibition Regulates the Actin Assembly Activity and Cellular Localization of Diaphanous-Related Formins
Mentor: Michael Rosen, M.D. and Helen Yin, M.D.
Current Position: Clinical Fellow, Internal Medicine, Rheumatology
Current Affiliation: Yale University School of Medicine

Tuhin Virmani
Dissertation Topic: Molecular And Functional Determinants Of Synaptic Vesicle Recycling In CNS Synapses
Mentor: Ege Kavalali, Ph.D.
Current Position: Postdoctoral Clinical Fellow/Assistant, Clinical Neurology
Current Affiliation: Columbia University Medical Center, New York

Jeff Waugh
Dissertation Topic:
 A Structural/Behavioral Analysis of Dopamine Regulation by the R7 RGS Subfamily
Mentor: Stephen Gold, Ph.D.
Current Position: 
Clinical Fellow, Neurology
Current Affiliation: Harvard University - Massachusetts General Hospital

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Class of 2006

Jeffrey B. Cheng 
Dissertation Topic: cDNA Cloning And Characterization Of Enzymes That Synthesize Bile Acids, Vitamin D And Waxes
Mentor: David Russell, Ph.D.
Current Position: Assistant Clinical Professor, Dermatology
Current Affiliation: University of California at San Francisco Medical Center

Jennifer Olson Graves
Dissertation Topic: The Molecular Mechanism of High Signaling Efficiency in Drosophila Photoreceptor Cells.
Mentor: Rama Ranganathan, Ph.D.
Current Position: Assistant Professor, Neurology (UCSF Adult & Pediatric MS Centers) 
Current Affiliation: UCSF Multiple Sclerosis Center, UC San Francisco Medical Center

Rohit Sharma
Dissertation Topic: The physical mechanism underlying long-range energetic interactions between sites in a protein.
Mentor: Rama Ranganathan, Ph.D.
Current Position: Resident, Clinical Genetics
Current Affiliation: Harvard University School of Medicine

Andrew I. Shulman
Dissertation Topic: Allosteric Communication in Retinoid X Receptor Heterodimers
Mentor: David Mangelsdorf, Ph.D.
Current Position: Staff Pediatric Rheumatologist
Current Affiliation: Children’s Hospital of Orange County (CHOC), Orange & Newport Beach, CA

Mark R. Steciuk
Dissertation Topic: The control of terminal bulb pumping in the nematodes C. elegans and P. redivivus
Mentor: Leon Avery, Ph.D. (Virgina Commonwealth University)
Current Position: Pathologist
Current Affiliation: Baptist Health, Jacksonville Pathology Consultants, PA , Jacksonville, FL

Rhea M. Sumpter, Jr.
Dissertation Topic: Viral and Host Genetic Determinants of Hepatitis C Virus Persistence and Interferon Resistance
Mentor: Michael Gale, Ph.D. (University of Washington)
Current Position: Instructor, Internal Medicine, Center for Autophagy Research
Current Affiliation: UT Southwestern

Elie A. Traer
Dissertation Topic: Regulation of cytochrome c release in UV-induced apoptosis
Mentor: Xiaodong Wang, Ph.D. (National Institute of Biological Sciences, Beijing)
Current Position: Instructor, Internal Medicine, Hematology & Medical Oncology
Current Affiliation: Oregon Health and Science University

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Class of 2005

Gene Devora
Dissertation Topic: Activating Murine NK Cell Receptors LY49H and LY49U and Their Potential Role in Friend Virus Resistance
Mentor: Michael Bennett, M.D.
Current Position: Allergist
Current Affiliation: Plano Internal Medicine Associates, Plano,TX

Ed Esplin
Dissertation Topic: Characterization of the Role of the PP2A-A Beta Gene, a Putative Tumor Suppressor, in Cell Growth and Tumorigenesis
Mentor: Glen Evans, M.D., Ph.D., and Marc Mumby, Ph.D.
Current Position: Clinical Scholar, Genetics
Current Affiliation: Stanford University

Jimmy L. Holder
Dissertation Topic: The bHLH/PPAS Transcription Factor SIM1 is a Novel Obesity Gene
Mentor: Andrew Zinn, Ph.D.
Current Position: Assistant Professor, Pediatric Neurology
Current Affiliation: Baylor College of Medicine, Houston, TX

Irfan Kathiriya
Dissertation Topic: GATA Co-factors: Collaborators in Cardiac Development, Conspirators in Cardiac Disease
Mentor: Deepak Srivastava, M.D. (UCSF)
Current Position: Clinical Instructor, Pediatric Anesthesiology
Current Affiliation: University of California at San Francisco Medical Center

Deepak Nijhawan
Dissertation Topic: Biochemical Pathways in Apoptosis
Mentor: Xiaodong Wang, Ph.D. (National Institute of Biological Sciences, Beijing)
Current Position: Assistant Professor, Internal Medicine/Hematology & Biochemistry
Current Affiliation: University of Texas Southwestern Medical Center, Dallas, TX

John Peters
Dissertation Topic: Casein Kinase 1 Transduces Wnt Signals
Mentor: Jon Graff, Ph.D.
Current Position: Pathologist
Current Affiliation: ProPath Pathology Services, Dallas, TX

Katherine Steger
Dissertation Topic: Cholinergic Regulation of Feeding in C. elegans: Studies of a T-type Calcium Channel and Three Muscarinic Acetylcholine Receptors
Mentor: Leon Avery, Ph.D. (Virginia Commonwealth University)
Current Position: Faculty, Psychiatry – Douglas Mental Health University Institute
Current Affiliation: McGill University Health Centre (Montreal, QC, Canada)

Matthew Wieduwilt
Dissertation Topic: Smad3 in Embryonic Patterning, Mesoderm Induction, and Colorectal Cancer in the Mouse
Mentor: Jon Graff, Ph.D.
Current Position: Assistant Clinical Professor, Internal Medicine, Hematology/Oncology
Current Affiliation: University of California at San Francisco Medical Center

Jon Willie
Dissertation Topic: Lessons from Sleepy Mice: Narcolepsy and the Orexin Neuropeptide System
Mentor: Masashi Yanagisawa, Ph.D.
Current Position: Assistant Professor, Neurological Surgery & Neurology (Emory Program in Sleep)
Current Affiliation: Emory University

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Class of 2004

Dara Aisner
Dissertation Topic: Regulation of hTERT, the Catalytic Subunit of Human Telomerase
Mentor: Jerry Shay, Ph.D.
Current Position: Assistant Professor, Pathology
Current Affiliation: University of Colorado School of Medicine, Denver, CO 

Vivek Arora
Dissertation Topic: Identification and Characterization of a Nef-Associated Kinase
Mentor: Jose Victor Garcia-Martinez, Ph.D.
Current Position: Faculty, Genitourinary Oncology; Lab Member – Dr. Charles L. Sawyer’s Lab
Current Affiliation: Memorial Sloan-Kettering Cancer Center & Research Laboratories, New York, NY

Adrienne Hammill
Dissertation Topic: Asymetric Cell Division Results in Differential Apoptotic Cell Fates in a B-Cell Lymphoma Model of Tumor Dormancy
Mentor: Richard Scheuermann, Ph.D.
Current Position: Assistant Professor, Pediatrics, Pediatric Hematology/Oncology; Integrated Research Pathway
Current Affiliation: Cincinnati Children's Hospital - University of Cincinnati College of Medicine

Mark Hatley
Dissertation Topic: Allosteric Determinants of Guanine Nucleotide Binding Proteins and Methods to Crystallize the Cytosolic Domains of Adenylyl Cyclase
Mentor: Al Gilman, Ph.D.
Current Position: Assistant Member, Pediatrics
Current Affiliation: St. Jude's Research Hospital, Memphis, TN

Jennifer Hodges
Dissertation Topic: Differential Effects of Thiazolidinediones on Gene Expression in Mouse and Rat
Mentor: J. Denis McGarry, M.D. (deceased) and Victoria Esser, M.D.
Current Position: Assistant Professor, Obstetrics/Gynecology
Current Affiliation: University of Colorado School of Medicine, Denver, CO

Mahesh Karandikar
Dissertation Topic: A Study of Mekk1: Scaffolding Protein and Raf-1 Activator
Mentor: Melanie Cobb, Ph.D.
Current Position: Neurosurgeon (Spinal Disease)
Current Affiliation: Mountain View Regional Hospital, Casper WY

Rafal Kedzierski
Dissertation Topic: Cardiovascular Role of Endothelin-A Receptor: Studies in Conditional Gene Knockout Mice
Mentor: Masashi Yanagisawa, Ph.D.
Current Position: General Radiologist, MRI focus
Current Affiliation: Medical Regional Hospital, Memphis, TN

Thomas Kerr
Dissertation Topic: Cholesterol 25-Hydroxylase and the In Vivo Role of Short Heterodimer Partner (SHP) in Bile Acid Metabolism
Mentor: David W. Russell, Ph.D.
Current Position: Assistant Professor, Medicine, Gastroenterology Division
Current Affiliation: Washington University School of Medicine, Barnes-Jewish Hospital

Lily Li
Dissertation Topic: The Role of Endonuclease G, a Mitochondrial Nuclease in Apoptosis
Mentor: Xiaodong Wang, Ph.D. (National Institute of Biological Sciences, Beijing)
Current Position: Dermatologist
Current Affiliation: US Dermatology Medical Group, Arlington, TX 

Timothy Lu
Dissertation Topic: Nuclear Receptor Regulation of Bile Acid Metabolism
Mentor: David Mangelsdorf, Ph.D.
Current Position: Assistant Medical Director, Research & Early Development (gRED)
Current Affiliation: Genentech

David McFadden
Dissertation Topic: Control of Cardiac and Limb Development by the bHLH Transcription Factors dHAND and eHAND
Mentor: Eric Olson, Ph.D.
Current Position: Instructor, Medicine, Endocrine Unit
Current Affiliation: Harvard University - Massachusetts General Hospital

Timothy Niacaris
Dissertation Topic: Serotonergic and G-Protein Mediated Regulation of the C. Elegans Pharyngeal Muscle Action Potential
Mentor: Leon Avery, Ph.D. (Virginia Commonwealth University)
Current Position: Assistant Professor, Orthopedic Surgery
Current Affiliation: University of North Texas Health Science Center, Forth Worth, TX

Adam Seegmiller
Dissertation Topic: Feedback Regulation of Lipid Biosynthesis by Drosophila Sterol Regulatory Element Binding Protein (dSREBP)
Mentors: Michael Brown, M.D. and Joseph Goldstein, M.D.
Current Position: Assistant Professor, Pathology, Microbiology & Immunology
Current Affiliation: Vanderbilt University Medical Center

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Class of 2003

Jared Abbott
Dissertation Topic: Active Site Analysis of Trypanosoma Brucei γ-Glutamylcysteine Synthetase 
Mentor: Meg Phillips, Ph.D.
Current Position: Dermatopathologist, Anatomic Pathology
Current Affiliation: Iowa Pathology Associates (Des Moines, IA)

Priscilla Chang
Dissertation Topic: Muscle-Specific Regulation of Serum Response Factor by Differential DNA Binding Affinity and Cofactor Interactions
Mentor: Eric Olson, Ph.D.
Current Position: Pathologist, Anatomic and Clinical Pathology/Hematopathology
Current Affiliation: Pathology Sciences Medical Group, Chico, CA 

Narimon Honarpour
Dissertation Topic: The Requirement of Apoptotic Protease Activating Factor-1 (APAF-1) for Mammalian Development
Mentor: Joachim Herz, Ph.D.
Current Position: Clinical Instructor, Medicine
Current Affiliation: University of California at Los Angeles Medical Center

Michael Lutter
Dissertation Topic: The Role of Mitochondrial Contact Sites in Bid Mediated Cytochrome C Release
Mentor: Xiaodong Wang, Ph.D. (National Institute of Biological Sciences, Beijing)
Current Position: Assistant Professor, Psychiatry
Current Affiliation: University of Iowa Carver College of Medicine

Holt Oliver
Dissertation Topic: Genetic and Biochemical Analyses of the Necessity for Caspase Activation by the Ced4-Domain Proteins, Apaf-1 and DARK
Mentor: Xiaodong Wang, Ph.D. (National Institute of Biological Sciences, Beijing)
Current Position:  Vice-President, Parkland Center for Clinical Innovation
Current Affiliation: Parkland Memorial Hospital, Dallas, TX

Gail Streater
Dissertation Topic: Elucidation of Functionally Important Amino Acids in the DNA DSBR and V(D)J Recombination Protein XRCC4
Mentor: Kathy Meek, D.V.M.
Current Position: Pediatrician, OSF Hospitalist Service
Current Affiliation: OSF St. Francis Medical Center (Peoria IL)

Renee Valdez
Dissertation Topic: Myogenic BHLH Transcription Factors: Their Overlapping Functions and Direct Regulation of MEF2C Provide a Regulatory Network for the Maintenance and Amplification of Vertebrate Myogenesis
Mentor: Eric Olson, Ph.D.
Current Position: Clinical Assistant Professor, Psychiatry & Behavioral Sciences
Current Affiliation: Baylor College of Medicine, Houston, TX 

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Class of 2002

Kevin Berman
Dissertation Topic: Studying Stress Responsive Signaling Pathways in C. elegans and Mammals
Mentor: Melanie Cobb, Ph.D.
Current Position: Dermatologist
Current Affiliation: Atlanta Center for Dermatologic Diseases, PA

Mickie Cheng
Dissertation Topic: Regulation of meiosis and cell cycle in the developmental context of spermatogenesis of Drosophila.
Mentor: Steve Wasserman, Ph.D.
Current Position: Assistant Adjunct Professor, Diabetes Center and Department of Medicine
Current Affiliation: University of California at San Francisco School of Medicine

Katrina Voe Cotton
Dissertation Topic: Translational regulation of HMG CoA reductase by a mevalonate-derived product
Mentors: Michael Brown, M.D. and Joseph Goldstein, M.D.
Current Position: Anesthesiologist
Current Affiliation: Medical City Dallas

Amber Luong
Dissertation Topic: Study of the regulation of 2 isoforms of the transcription factor, SREBP-1
Mentors: Michael Brown, M.D. and Joseph Goldstein, M.D.
Current Position: Assistant Professor, Otorhinolaryngology and Immunology
Current Affiliation: University of Texas Health Science Center, Houston - MD Anderson Cancer Center

David Myers
Dissertation Topic: Mapping the Energetics of Dimerization of Trypanosoma brucei Ornithine Decarboxylase.
Mentor: Meg Phillips, Ph.D.
Current Position: Clinical Assistant Professor, Internal Medicine - Pulmonary Division
Current Affiliation: UT Southwestern

Ben Ohlstein
Dissertation Topic: A role for the Drosophila Bag-of-Marbles and Benigh Gonial Cell Neoplasm genes in the differentiation of cystocytes from germline stem cells.
Mentor: Dennis McKearin, Ph.D. (HHMI)
Current Position: Assistant Professor, Genetics and Development
Current Affiliation: Columbia University Medical Center, New York, NY

Andrew Rozelle
Dissertation Topic: Phosphatidylinositol 4,5 bisphosphate induces actin-based movement of endocytic and exocytic vesicles enriched in sphingolipid: Cholesterol rafts through WASP family proteins and the Arp 2/3 complex.
Mentor: Helen Yin, Ph.D.
Current Position: Rheumatologist
Current Affiliation: Palo Alto Medical Foundation (Palo Alto, CA/Fremont, CA)

Jason Walenta
Dissertation Topic: Hooking Organelles to Microtubules
Mentor: Helmut Krämer, Ph.D.
Current Position: Psychiatrist (last known)
Current Affiliation/Location: Reno, NV

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Class of 2001

Hal Berman
Dissertation Topic: Regulation of glucose disposal in hepatocytes and Islets of Langerhans studied by metabolic engineering
Mentor: Chris Newgard, Ph.D. (Duke)
Current Position: Assistant Professor, Surgical Pathology and Cancer Research
Current Affiliation: University of Toronto Medical Center

Derek Byers
Dissertation Topic: The cytotoxic T lymphocyte response to a viral peptide presented by H2-M3
Mentor: Kirsten Fischer Lindahl, Ph.D.
Current Position: Assistant Professor of Internal Medicine, Division of Pulmonary and Critical Care Medicine
Current Affiliation: Washington University School of Medicine

Tom D'Orazio
Dissertation Topic: A study of the camerosplenic axis of Anterior Chamber-Associated Immune Deviation (ACAID)
Mentor: Jerry Niederkorn, Ph.D.
Current Position: Ophthalmologist; Clinical Staff
Current Affiliation: Crossroads Eye Care Associates (McMurray, PA); University of Pittsburgh Medical Center, Shadyside Hospital

Alex Duncan
Dissertation Topic: A biochemical dissection of the heterotrimeric G protein thioacylation cycle
Mentor: Al Gilman, Ph.D.
Current Position: Clinical Assistant Professor, Internal Medicine, Division of Infectious Diseases
Current Affiliation: University of North Carolina School of Medicine

David Edwards
Dissertation Topic: Intracellular protein-protein interactions involved in the establishment of dorsoventral polarity during Drosophila melanogaster embryogenesis
Mentor: Steven Wasserman, Ph.D. (UCSD)
Current Position: Cardiologist
Current Affiliation: Johns Hopkins University School of Medicine 

Greg Goldmakher
Dissertation Topic: Electrophysiological characterization of the voltage- and GABA-induced currents of periglomerular neurons of the rat accessory olfactory bulb
Mentor: Robert Moss, Ph.D. (Deceased)
Current Position: Associate Director, Medical Affairs (Radiology)
Current Affiliation: ICON Medical Imaging, Warrington, PA

Adrian Goldstein
Dissertation Topic: CAATT displacement protein regulates B-lymphocyte and T-lymphocyte development
Mentor: Richard Scheuermann, Ph.D.
Current Position: Director, Dermatopathology
Current Affiliation: D-PATH, Memphis, TN 

Greg Hosler
Dissertation Topic: Minimal residual disease evaluation as a prognostic indicator in T Cell acute lymphoblastic leukemia
Mentor: Richard Scheuermann, Ph.D.
Current Position: Clinical Assistant Professor, Pathology and Dermatology
Current Affiliation: UT Southwestern

Laura Klesse
Dissertation Topic: Neurotrophin signaling cascades
Mentor: Luis Parada, Ph.D.
Current Position: Assistant Professor of Pediatrics (Pediatric Hematology/Oncology)
Current Affiliation: UT Southwestern-Children’s Medical Center

Bobby Korn
Dissertation Topic: SCAP, A sterol sensing protein that regulates cholesterol homeostatis in the liver
Mentors: Michael Brown, M.D. and Joseph Goldstein, M.D.
Current Position: Assistant Clinical Professor of Ophthalmology (Orbit and Reconstructive Surgery)
Current Affiliation: University of California at San Diego Medical Center School of Medicine

Steven Russell
Dissertation Topic: Role of the proteasome in gene transcription and DNA repair
Mentor: Stephen Johnston, Ph.D. (Arizona State University Biodesign Institute)
Current Position: Instructor, Internal Medicine, Division of Endocrinology
Current Affiliation: Harvard University - Massachusetts General Hospital

Greg Van Dyke
Dissertation Topic: Study of the mechanisms by which CD8 T lymphocytes suppress the replication of HIV in CD4 T cells
Mentor: Ellen Vitetta, Ph.D.
Current Position: Assistant Clinical Professor, Medicine and Pathology
Current Affiliation: University of California at Los Angeles Medical Center School of Medicine

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Class of 2000

Beth Duncan
Dissertation Topic: Identification and characterization of the sites of regulated proteolysis in SREBP-2
Mentors: Michael Brown, M.D. and Joseph Goldstein, M.D.
Current Position: Fellow in Allergy and Immunology Departments 
Current Affiliation: University of North Carolina School of Medicine

Alex Faulkner Lazar
Dissertation Topic: A New Family of Lipid Phosphate Phosphatases: What DO they Do
Mentor: Paul Sternweis, Ph.D.
Current Position: Associate Professor of Pathology; Director, Sarcoma Molecular Diagnostics; Director, Soft Tissue Pathology Fellowship Program; Sarcoma Research Center
Current Affiliation: University of Texas Health Science Center, Houston - MD Anderson Cancer Center

Rene Galindo
Dissertation Topic: Genetic and molecular analysis of dorsoventral signaling in the Drosophila embryo
Mentor: Steven Wasserman, Ph.D.
Current Position: Assistant Professor of Pediatric Pathology and Molecular Oncology
Current Affiliation: UT Southwestern

Richard (Dick) Kibbey
Dissertation Topic: The LDL receptor clustering motif interacts with the clathrin terminal domain in a reverse turn conformation.
Mentor: RGW Anderson. M.D.
Current Position: Assistant Professor of Internal Medicine (Section of Endocrinology) and Cellular