Disease-Oriented Teams

At UT Southwestern’s Simmons Comprehensive Cancer Center, individual clinicians and researchers are woven into multidisciplinary teams that bring broad expertise to bear on scientific and clinical challenges unique to different cancers. The Cancer Center supports 10 such disease-oriented teams (DOTs), each of which focuses on a major cancer type and provides a comprehensive approach to the care of cancer patients.

DOTs coordinate and define standards of care at the Cancer Center for:

  • Breast cancer
  • Gastrointestinal cancers
  • Genitourinary cancers
  • Gynecologic malignancies
  • Head and neck cancers
  • Hematologic malignancies and stem cell transplantation
  • Lung cancer
  • Melanoma/sarcoma
  • Neurological cancers
  • Pediatric cancers

The DOTs are composed of medical, surgical, and radiation oncologists; pathologists; translational scientists; research nurses; study coordinators; clinical support personnel such as social workers and genetics counselors; and data specialists. Each team reviews clinical trial concepts, including investigator-initiated trials, cooperative group trials, and industry-sponsored studies, and prioritizes and monitors studies for their specific disease site. Clinical trials range from first-line treatments to advanced-stage cancer therapies, and also include prevention and new-agent trials.

These teams also are incubators for new ideas in the fight against cancer, including investigations in areas such as biomarkers and strategies to reduce cancer deaths. The DOTs work closely with basic science investigators to foster translational research, helping to develop promising discoveries made at UT Southwestern into practical treatment advances.