Research at Simmons Comprehensive Cancer Center

The Simmons Comprehensive Cancer Center is a “matrix” cancer center, which fosters routine interaction across scientific disciplines. This ensures research discoveries are broadly leveraged to promote new progress in the fight against cancer.

These transdisciplinary interactions, along with overall depth and breadth of research, are key attributes underlying Simmons’ designation by the National Cancer Institute as one of a select group of “Comprehensive” U.S. cancer centers.

The Simmons Cancer Center has more than 180 full members. Member scientists include one Nobel Laureate, nine members of the National Academy of Sciences, four members of the National Academy of Medicine (formerly the Institute of Medicine), and nine Howard Hughes Medical Institute investigators.

The Cancer Center benefits from a broad base of institutional, philanthropic, community, and governmental support. Since 2010 a unique state agency, the Cancer Prevention and Research Institute of Texas, has fueled vigorous scientific efforts against cancer across the state. To date, funding from the institute to support UT Southwestern cancer research and prevention initiatives has surpassed $315 million.

Scientific Programs

Five Scientific Programs, supported by a Cancer Center Support Grant from the National Cancer Institute, are at the heart of the Simmons Comprehensive Cancer Center’s research endeavors:

Other Research

Investigators at Simmons Comprehensive Cancer Center are driving innovative research and developing new standards in cancer care across disciplines and cancer types:

Shared Resources

In addition to a Clinical Research Office, six Shared Resources support Simmons Comprehensive Cancer Center members conducting basic, translational, or clinical research. These resources provide cost-effective access to cutting-edge expertise and technology: 

Members also have access to a range of University-wide supported cores.

Specialized Programs of Research Excellence (SPOREs)

Simmons Comprehensive Cancer Center is home to two SPOREs, programs that are funded by the National Cancer Institute to promote collaborative, interdisciplinary translational research focused on specific organ sites or groups of related cancers:

Clinical Trials

The clinical research infrastructure at Simmons Comprehensive Cancer Center includes a Phase I Clinical Trials Unit that helps shepherd the most promising potential cancer therapies through early-stage development. The Cancer Center has a broad range of clinical trials open to eligible patients.