For 30 years, the General Clinical Research Center (GCRC) at UT Southwestern Medical Center provided a highly successful platform for translational research. GCRC investigators made major contributions to the therapeutic advancement of numerous commonly used drugs, including statins, 5-reductase inhibitors, and calcium supplements. In 2007, the GCRC was incorporated into the Clinical and Translational Research Center (CTRC), which greatly expanded the resources and facilities available to support clinical research. The major components of the CTRC are shown in the following figure.
The CTRC is a streamlined, consolidated, and centralized institutional and investigational resource. It assists investigators in all stages of protocol development and implementation.
The CTRC is an institutional resource for clinical and translational research available to UT Southwestern faculty physicians, residents, and fellows; medical and graduate students; and faculty and students from the Center for Translational Medicine's partnering institutions who wish to perform clinical research that requires a controlled environment for their investigations while supporting the safe and ethical conduct of clinical research and enhancing the quality of the research experience for study participants.
The Inpatient Clinic represents the facility that previously was the GCRC. Because of increased outpatient research at UT Southwestern, multiple outpatient clinics are now available to translational researchers.
The CTRC has recently been expanded to include Population Resources including the Dallas Heart Study and a Multiethnic Biobank. To make the CTRC more accessible to UT Southwestern investigators, a CTRC Laboratory has been added that provides phlebotomy services, processing of sample, and banking of body fluids, cells, and DNA and RNA.
The CTRC interacts with other Center for Translational Medicine programs as part of the latter’s efforts to provide the crucial infrastructure necessary for medical scientists to discover and apply new diagnostics and therapeutics for the detection, diagnosis, treatment, and prevention of disease and effective therapies.