UT Southwestern Medical Center researchers have identified a feedback loop that precisely maintains levels of a metabolite essential for many cellular processes. Their basic science findings could have implications for many diseases, including cancer.
UTSW researchers have determined that cellular modifications of histones, a class of proteins that package our DNA, serve an unexpected metabolic function.
A study by UT Southwestern Medical Center scientists describes noncoding mutations in regulatory DNA sequences that protect against the adverse effects of pulmonary fibrosis, a lung disease.
UT Southwestern researchers have solved the crystal structure of the yeast version of a protein that is crucial for human development.
UT Southwestern Medical Center researchers have found that a small number of mutated RNA molecules can have major consequences on neurodegenerative conditions such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
Researchers at UT Southwestern Medical Center have demonstrated a pathway by which abdominal fat, in particular fat surrounding the internal organs, may lead to type 2 diabetes.
Researchers at the Peter O’Donnell Jr. Brain Institute at UT Southwestern Medical Center have compiled a review outlining how a specific form of protein increases the risk of developing Alzheimer’s disease.
A molecule that helps neurons communicate also controls how quickly brain cells reform neurotransmitter-storing packets needed to continue messaging with other cells, according to a new study from researchers at the Peter O’Donnell Jr. Brain Institute at UT Southwestern Medical Center.
Researchers at UT Southwestern Medical Center and collaborators report a significant advance in the synthesis of nitrogen-containing chemical compounds, which represent a majority of chemicals.
Researchers have identified a molecule in the skin that could strengthen the body’s immune response by repairing the thymus.