Health Watch - Fighting Cancer: Endometrial Cancer

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The war against cancer continues in laboratories and hospitals. This week on Health Watch, we’ll talk about some important victories in this war. Endometrial cancer is the most common cancer of the female reproductive tract, and it can kill within a year. A recent discovery may help improve treatment for some women.

Endometrial cancer affects the lining of the uterus and can develop into ovarian cancer. About a fifth of women with this cancer respond well to treatment with a particular class of drugs, but doctors didn’t know which women would respond. Researchers at
UT Southwestern Medical Center have found that a mutation in a single gene causes the kinds of cancer that respond to these drugs.

Dr. Diego Castrillon, a UT Southwestern pathologist, says this discovery could allow doctors to determine which patients are most likely to respond to treatment. This would also mean that women who aren’t likely to respond wouldn’t be subjected to unnecessary chemotherapy.


April 2010

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