Awards for September 2013

Federal Awards – September 2013

September Awards

Adinoff, Bryon, NIH, Lidocaine as a Treatment for Cocaine Relapse and Craving, $224,408; Altschuler, Steven, NIH, Lung Cancer Heterogeneity and Its Impact on Drug Resistance, $423,044; Amatruda, James, Children’s Hosp of Philadelphia/NIH, NIH COG Chair Grant, $5,400; Attanasio, Massimo, NIH, Role of GLIS2 in Development of Cystic Kidney Disease, $333,722; Bachoo, Robert, NIH, Genetic Dissection of Glioblastoma: Cell of Origin, $329,873; Beutler, Bruce, Scripps Res Inst/NIH, Systems Approach to Immunity and Inflammation; Project 1, $829,734; Beutler, Bruce, Scripps Res Inst/NIH, Systems Approach to Immunity and Inflammation; Core A, $786,180; Beutler, Bruce, Scripps Res Inst/NIH, Systems Approach to Immunity and Inflammation; Core C, $306,173.

Booth, Timothy, Children’s Hosp of Philadelphia/NIH, Diagnostic Imaging Review: NIH COG Chair Grant, $80; Boothman, David, NIH, Ku70 Binding Protein-5 (KUB5), Novel Factor in Nonhomologous End Joining – Diversity Supplement, $74,450; Brown, Sherwood, NIH, Icariin to Prevent Corticosteroid-Related Memory Changes, $226,575; Brown, Sherwood, NIH, Antidepressant Treatment at Inner City Asthma Clinic, $20,578; Byerly, Matthew, Columbia Univ/NIH, 2/2: Comparison of Long-Acting Injectable Medication for Schizophrenia (ACLAIMS), $10,640; Carroll, Thomas, NIH, Interactions Between Stroma and Progenitor Cells During Kidney Development – Diversity Supplement, $16,064.

Chook, Yuh Min, Rockerfeller Univ/NIH, Nucleocytoplasmic Transport: Target for Cellular Control, $138,484; Cobb, Melanie (Fellow M. Kalwat), NIH, Role of isoxazole compounds in beta cell differentiation and function, $49,214; Dowling, Michael, Washington Univ in St. Louis/NIH, Silent Cerebral Infarct Multi-Center Clinical Trial – Neurology Committee, $1,979; Dowling, Michael, Washington Univ in St. Louis/NIH, Silent Cerebral Infarct Multi-Center Clinical Trial, $1,155; Elmquist, Joel (Fellow C. Javadi), NIH, Leptin and Insulin Responses in Hypothalamic NPY Neurons, $12,795; Euhus, David, Dana-Farber Cancer Inst/NIH, Novel Tools for Familial Risk Prediction, $24,354.

Falck, J Russell, Vanderbilt Univ/NIH, Role of Icosanoids in Renal Function – Core C, $39,019; Falck, J Russell, Med College of Wisconsin/NIH, ETT-Induced Cardioprotection: Role of Opoids and Nitric Oxide (NO), $23,578; Feranchak, Andrew, NIH, Mechanosensitive Signaling and Cholangiocyte Secretion, $318,000; Flores, Glenn, Amer Academy of Pediatrics/NIH, APA Research in Academic Pediatrics Initiative on Diversity (RAPID), $22,901; Frankel, Arthur, Advanced Targeting Systems/NIH, Development of Novel Cancer Pain Therapeutic – ARRA Stimulus BRDG-SPAN, $965,736; Galindo, Rene, NIH, Minority Predoctoral NLHBI Research Training at UT Southwestern, $5,682.

Gardner, Kevin, NIH, Mechanistic principles of signal detection and transmission in bacterial two-component systems, $325,438; German, Dwight, NIH, Diagnostic and prognostic biomarkers for Parkinson's disease (MPI), $677,884; Goldsmith, Elizabeth, NIH, Chloride Sensing by WNK Kinases, $278,250; Greenberg, David, Emory Univ/NIH, Tracking Human Cardiac Subtype Specification Using Molecular Beacons, $16,791; Hall, Christiana, Univ of Virginia/NIH, Stroke Hyperglycemia Insulin Network Effort (SHINE) Trial, $372,020; Hall, Christiana, Univ of Cincinnati/NIH, Ethnic/Racial Variation in Intracerebral Hemorrhage (ERICH), $53,047; Halm, Ethan, Agency for Healthcare Res & Qual, UT Southwestern Center of Patient-Centered Outcomes Research (PCOR), $999,997.

Hobbs, Helen (Fellow M. Mitsche), NIH, Determining Function of PNPLA3 Utilizing Metabolomics and Stable Isotope Labeling, $103,204; Hofmann, Sandra, Washington Univ in St. Louis/NIH, Pathophysiology and Novel Therapies for Batten's Disease, $62,656; Hooper, Lora (Fellow D. Propheter), NIH, Antibacterial function of Resistin-like molecule beta in the intestine, $52,190; Hsieh, Jer-Tsong, NIH, Developing targeted therapy with prostate cancer specific nanoMED, $327,859; Hu, Ming Chang, NIH, Klotho: Therapeutic Agent for Ischemia Reperfusion Induced Acute Kidney Injury, $333,722; Huber, Kimberly, NIH, Role of MEF2 and neural activity in cortical synaptic weakening and elimination, $415,385.

Igarashi, Peter, NIH, Renal Control of Body Composition and Blood Pressure (MPI), $96,647; Igarashi, Peter, NIH, UT Southwestern O'Brien Kidney Research Core Center – Summer Supplement, $25,920; Jarrett, Robin (Fellow A. Raja), Natl Science Fdn, Graduate Research Fellowship Program, $44,000; Kavalali, Ege (Fellow D. Crawford), NIH, Role of spontaneous neurotransmission in synaptic plasticity and behavior, $49,214; Kim, Taekyung, NIH, Epigenetic mechanism of enhancer RNA in behavioral plasticity, $347,813; Kowalske, Karen, U.S. Dept of Education, North Texas Burn Rehabilitation Model System, $383,000.

Kraus, William, NIH, Activity of Nuclear Receptor Coregulators with Chromatin, $383,072; Kutz, Joe, Nationwide Children’s Hosp/NIH, Virtual Temporal Bone Surgery: Defining and Translating Standardized Metrics to Automated Assessment Tool, $8,500; Lee, William, NIH, Multi-Center Group to Study Acute Liver Failure, $2,500,000; Lee, William, NIH, North Texas Hepatitis B Consortium: Clinical Site for Hepatitis B Network, $244,388; Levine, Benjamin, Natl Space Biomed Res Inst, Cardiovascular Imaging and Strategies to Mitigate Risk for Cardiac Events in Astronauts during Prolonged Spaceflight, $371,905; Levine, Benjamin, NASA, Cardiac Atrophy and Diastolic Dysfunction During and After Long Duration Spaceflight: Functional Consequences for Orthostatic Intolerance and Risk of Cardiac Arrhythmias, $157,221; Levine, Benjamin (Fellow J. Lawley), Natl Space Biomed Res Inst, Microgravity Induced Visual Alterations and Intracranial Pressure, $50,000.

Lu, Christopher, NIH, Mitochondrial AntiViral Signaling Protein, IRF1, and Ischemic AKI, $159,000; Lu, Hanzhang, UT Dallas/NIH, Neuroimaging of Dedifferentiation and Memory Across Lifespan, $18,252; Lu, Hanzhang, Baylor College of Med/NIH, Neurobehavioral Outcome of Head Injury in Children, $16,409; Lu, Richard, NIH, Molecular Mechanisms of Oligodendrocyte Differentiation and Myelination, $328,926; Macdonald, Raymond, Univ of Utah/NIH, Epigenetic switch controlling pancreatic cancer susceptibility, $34,583; Mangelsdorf, David, Univ of Michigan/NIH, Activation of Androgen Biosynthesis and Drug Metabolism by Cytochrome b5 – ARRA Stimulus Other, $10,303;

McCavit, Timothy, Washington Univ in St. Louis/NIH, Silent Cerebral Infarct Multi-Center Clinical Trial, $3,654; Mendell, Joshua, Johns Hopkins Univ/NIH, Functional Annotation of Pancreatic Cancer Genome, $119,848; Miller, Richard, NIH, Biophysical Properties of Renal Glomeruli and Podocytes, $501,982; Minna, John, NIH, SPORE in Lung Cancer – Supplement, $560,104; Monteggia, Lisa, NIH, MeCP2 Dependent Transcriptional Repression & Neurotransmission, $397,500; Muppidi, Srikanth, Univ of Miami/FDA, Effectiveness of Prednisone for Treatment of Ocular Myasthenia (EPITOME), $8,384.

Niederkorn, Jerry, NIH, Core Grant for Vision Research, $610,481; Nijhawan, Ank, LIFESPAN/NIH, Improving linkage to care following release from incarceration, $105,166; North, Carol, Texas Dept. of State Health Svc/CDC, 2012 Disaster Behavioral Health Training Conference, $600; Olson, Eric, NIH, Metabolic Control by Myogenic MicroRNAs, Mediator and Myokines (MPI), $473,800; O'Suilleabhain, Padraig, Massachusetts General Hosp/NIH, Coenzyme Q10 in Huntington's Disease, $1,270; Otwinowski, Zbyszek, Northwestern Univ/NIH, Center for Structural Genomics of Infectious Diseases, $28,858.

Potts, Ryan, U.S. Dept of Defense, Role of Germline MAGE Cancer-Testis Antigens in Colorectal Cancer, $159,000; Rakheja, Dinesh, Johns Hopkins Univ/NIH, Determining Roles of ATRX and DAXX Abnormalities in Cancer Telomere Biology, $13,343; Ramos-Roman, Maria, NIH, Effect of Lactation on Ectopic Lipid After Gestational Diabetes, $198,750; Rosen, Michael (Fellow C. Pak), NIH, Determining Structural Topology of Nephrin-Receptor-Signaling Complexes, $53,942; Scaglioni, Pier (Fellow J. Constanzo), NIH, SUMO Ligase PIAS1: An Unexpected Role In Mouse Embryogenesis and Cancer Survival, $29,744; Scherer, Philipp, NIH, Novel Mechanisms Regulating the Adipocyte-Brain Hepatocyte Axis (Project 2) – Diversity Supplement, $85,701; Scherer, Philipp (Fellow J. Xia), NIH, Intracrine metabolic effects of adiponectin mutants, $29,712.

Takarae, Yukari, NIH, Electrophysiological Correlates of Cognitive Control in Autism, $127,805; Teiber, John, U.S. Dept of Defense, Maintenance of Paraoxonase 2 Activity as Strategy to Attenuate P. Aeruginosa Virulence, $319,096; Toto, Robert, NIH, UT Southwestern Center for Translational MED – UL1, $2,972,396; Toto, Robert, NIH, UT Southwestern Center for Translational MED – KL2, $703,543; Toto, Robert, NIH, UT Southwestern Center for Translational MED – TL1, $105,899; Toto, Robert, Univ of Utah/NIH, Pulse Wave Velocity and Central Aortic Pressure Outcome in SPRINT, $1,080.

Tu, Benjamin, Johns Hopkins Univ/DARPA, CLIO Gene Guard Thrust, $102,759; Whitehurst, Angelique, NIH, Mechanistic Elaboration of Fragility in the Cancer Cell Mitotic Spindle, $267,939; Willson, James, Case Western Reserve Univ/NIH, Targeting 15-PGDH in Colon Cancer Prognosis, Prediction, Treatment and Prevention, $98,621; Willson, James, NIH, Cancer Center Support Grant – CTRP Data Registration Supplement, $75,000.

Wolf, Steven, U.S. Dept of Defense, Combination Therapies for Mitigation of Musculoskeletal Pathologic Damage in Novel Model of Severe Injury and Disuse, $159,206; Xiao, Guanghua, NIH, Integrative Analysis to Identify Therapeutic Targets for Lung Cancer, $329,925; Zhang, Song, Natl Science Fdn, III: Medium: Collaborative Research: Robust Large-Scale Electronic Medical Record Data Mining Framework to Conduct Risk Stratification for Personalized Intervention, $60,703; Zhu, Hao, NIH, Metabolic roles for Lin28-let-7 miRNA pathway in sarcoma tumorigenesis, $26,779.

Nonfederal Awards – September 2013

Ahn, Chul, CPRIT, C1: Biostatistical Core, $52,321; Amatruda, James, CPRIT, P3: Functional Validation of Actionable Mutations in Sarcoma Genetic Model Systems, $335,078; Amatruda, James, CPRIT, C1: Central Sarcoma Processing Core, $158,888; Amatruda, James (Fellow K. Chen), Damon Runyon Cancer Res Fdn, Dysregulation of the N-myc/Lin28/let-7 axis in childhood Wilms tumors, $62,000; Argenbright, Keith, Univ of North Texas Health Sci Ctr/CPRIT, Comprehensive Breast Cancer Prevention for High Risk Women in Dallas County, $106,844; Bai, Xiaoying, CPRIT, Recruitment of First-Time, Tenure-Track Faculty Members, $358,989.

Chen, Zhijian, CPRIT, P3: Mechanisms Underlying Inflammation and Cell Death in Cancer, $301,952; Chen, Zhijian, CPRIT, C2: Proteomics Core, $204,831; Chen, Zhijian (Fellow J. Wu), Howard Hughes Med Inst, 2013 HHMI International Predoc Fellows, $43,000; Chen, Zhijian (Fellow X. Cai), Howard Hughes Med Inst, Regulation of MAVS in Antiviral Signaling, $43,000; Cheng, Edaire (Fellow N. Nguyen), Amer Academy of Pediatrics, Effects of proton pump inhibitor treatment on esophageal, $3,000; De Brabander, Jef, CPRIT, C1: Chemistry and Pharmacology Core, $209,970.

Euhus, David, CPRIT, Cancer Genetics Services for Rural and Underserved Populations in Texas, $529,112; Fontoura, Beatriz, CPRIT, P2: Intersections between Viral-Host Interactions and Oncogenic Pathways as Molecular Targets for Chemical Intervention, $315,789; Goodman, Joel, Amer Diabetes Assoc, The Cell Biology of Lipid Storage, $37,454; Gupta, Samir, CPRIT, Evidence-Based Colorectal Cancer Screening for Uninsured, $698,261; Hsieh, Jer-Tsong, CPRIT, C1: Translational Core, $203,871; Iannaccone, Susan, Nationwide Children’s Hosp/Muscular Dystrophy Assoc, MDA DMD Network, $60,000.

Iyengar, Puneeth, Sidney Kimmel Fndtn for Cancer Res, Development of Genomic Signature for Predicting Cachexia-Inducing Solid Tumors to Facilitate Early Therapeutic Intervention, $98,918; Jain, Raksha, Gilead Sciences Inc, Hormone Effects on Response to Pseudomonas Infection in Cystic Fibrosis, $65,000; Kittler, Ralf, CPRIT, P3: Characterization of Cancer-Specific Gene Programs Regulated by Nuclear Receptors and Co-Regulators, $160,004; Lavery, Lawrence, Hamad Med Corp, Novel Stimulator Socks for Improving Balance in Diabet, $143,574; Levine, Beth, CPRIT, P1: Selective Autophagy Molecules as Multifunctional Regulators of Innate Immunity and Oncogenesis, $315,264; Liu, Xin, CPRIT, Recruitment of First-Time, Tenure-Track Faculty Members, $500,000.

Liu, Zhi-Ping, CPRIT, P1: Targeting Epigenetic Co-Activators of Ar with Small Molecule Inhibitors, $209,216; Liu, Zhi-Ping, CPRIT, AC: Epigenetic Mechanisms and Therapeutic Strategies for Targeting Prostate Cancer, $46,973; Mangelsdorf, David, CPRIT, AC: Development of Nuclear Receptors and CoRegulators as Diagnostic and Therapeutic Targets in Breast and Lung Cancers, $56,143; Mason, Ralph, CPRIT, P3: Effects of Hypoxia, $245,561; Minna, John, CPRIT, P1: Characterization of Nuclear Receptor and Co-Regulator Expression and Function in Lung Cancers, $411,516; Mirzaei, Hamid, CPRIT, Recruitment of Missing Links, $300,000.

Morrison, Sean, CPRIT, Recruitment of Established Investigators, $2,000,000; Munshi, Nikhil, Burroughs Wellcome Fund, Genomic Approaches to Understanding Cis-Regulatory Architecture of Atrioventricular Node, $140,000; Potts, Ryan, CPRIT, Recruitment of First-Time, Tenure-Track Faculty Members, $465,000; Powell, Craig (Fellow H. Speed), AUTISM SPEAKS, Preclinical Therapeutic Target Validation of Glutamate Receptors in Shank3 Models of Autism, $58,900; Rizo-Rey, Jose, CPRIT, P3: Molecular and Structural Basis of Epigenetic Regulation of AR, $263,157; Roland, Peter, Duke Univ/Amer Acad of Otolaryngology, Sudden Hearing Loss Guideline (CHEER), $2,200.

Sharma, Preeti, Cystic Fibrosis Fdn, Cystic Fibrosis Care, Teaching and Research Center, $110,470; Siegwart, Daniel, CPRIT, Recruitment of First-Time, Tenure-Track Faculty Members, $366,809; Skapek, Stephen, CPRIT, P2: High Throughput Screening for Sarcoma Cell Proliferation and Survival Factors, $268,800; Skapek, Stephen, CPRIT, AC: Molecularly Targeted Therapy for Soft Tissue Sarcoma in Texas, $130,430; Solberg, Timothy, CPRIT, C3: Image Guided Irradiation of Small Animals, $175,510; Tambar, Uttam, Amer Chemical Soc, Enantioselective Allylic Amination of Olefins, $50,000.

Thorpe, Philip, CPRIT, P4: Radiation-Guided Vascular Targeting of Lung Cancer, $262,827; Timmerman, Robert, CPRIT, AC: Exploiting Radiobiology of Stereotactic Ablative Radiotherapy for Lung Cancer, $61,192; Tu, Benjamin (Fellow C. Lee), Howard Hughes Med Inst, 2013 HHMI International Predoc Fellows, $43,000; Wang, Jing, Amer Cancer Soc, High Quality Low-dose CBCT for Image-Guided and Adaptive Radiation Therapy, $177,915; Wang, Zhigao, CPRIT, Recruitment of First-Time, Tenure-Track Faculty Members, $500,000; White, Michael, CPRIT, AC: Innate Immunity and Cancer, $78,947.

Word, Ann (Fellow M. Good), Amer Urogynecologic Soc Fndtn, Fibulin-5 Enhances Wound Healing in the Vaginal Vault, $25,000; Xie, Yang, CPRIT, C2: Biostatistics, Bioinformatics and Database Core, $149,988; Yu, Hongtao, CPRIT, P2: Mechanism and Inhibition of LSD1-Dependent Transcription of AR Target Genes in Prostate Cancer Cells, $270,839; Zhu, Hao, CPRIT, Recruitment of First-Time, Tenure-Track Faculty Members, $400,000.

Industry Sponsored Awards, dollar amounts not available – September 2013

Abu-Hijleh, Muhanned, Study to Evaluate IBV Valve System for Single-Lobe Treatment of Severe Emphysema; Beg, Muhammad, Ph2 Study of SGI-110 in Treatment of Advanced Hepatocellular Carcinoma (HCC) Sbjs Who Failed Prior Treatment With Sorafenib; Carr, Bruce, Ph2b Study of Elagolix in Premenopausal Women with Heavy Menstrual Bleeding Associated with Uterine Fibroids; Chin, Kelly, Phase 3b Study of Macitentan in Pts with Pulmonary Arterial Hypertension to psychometrically validate the PAH-SYMPACT instrument SYMPHONY; Emslie, Graham, Evaluation of Vilazodone in Adolescent Pts with Major Depressive Disorder; Hannan, Raquibul, Ph2 Trial of Sipuleucel-T and Stereotactic Ablative Body Radiation (SABR) for Pts with metastatic castrate-resistant Prostate Cancer (mCRPC).

Iannaccone, Susan, Phase 3 Study of Ataluren (PTC124) in Pts with Nonsense Mutation Dystrophinopathy; Jain, Mamta, EGRIFTA Long Term Observational Study; Mansour, John, Ph3 Study of Folfirinox With or Without HyperAcute-Pancreas Immunotherapy in Sbjs with Borderline Resectable or Locally Advanced Unresectable Pancreatic Cancer; Mayo, Marlyn, Ph2 Study of LUM001 in Combination with Ursodeoxycholic Acid in Pts with Primary Biliary Cirrhosis; Raskin, Philip, Sub-Study of ITCA 650 in Pts with Type 2 Diabetes with High Baseline HbA1c.

Schiller, Joan, Ph3b Trial of continuous bevacizumab treatment beyond progression of disease (PD) in pts with advanced non-squamous non-small lung cancer; Schiller, Joan, Ph2 Study of Neratinib and Neratinib Plus Temsirolimus in Pts with Non-Small Cell Lung Cancer Carrying Known HER2 Activating Mutations; Szmuk, Peter, Ph4 Study of Oxycodone Oral Solution in Pediatric and Adolescent Subjects; Welch, Babu, Surpass Intracranial aneurysm Embolization System Pivotal Trial to Treat Large or Giant Wide Neck Aneurysms (The SCENT Trial).