Awards for May 2013

Federal Awards

Ariizumi, Kiyoshi, NIH, DC-HIL in Cutaneous Immunity, $15,741; Baker, Linda, NIH, Near-Infrared Spectroscopy for Pediatric Acute Scrotum and Testicular Torsion, $191,794; Baum, Michel, NIH, Neonatal Proximal Tubular Acidification (MPI), $19,578; Bibb, James, NIH, NMDA Receptor Regulation in Addiction, $19,080; Bobulescu, Ion, NIH, Protein Phosphatase Regulation of Principal Renal Sodium Transporter NHE3, $86,847; Boothman, David, NIH, Ku70 Binding Protein-5 (KUB5), Novel Factor in Nonhomologous End Joining, $75,207; Brilakis, Emmanouil, NIH, Effect of Extended-Release Niacin on Saphenous Vein Graft Atherosclerosis, $237,505; Brown, Kathlynn, NIH, Suite of Tumor-Targeting Peptides for Personalized Therapy of Lung Cancer, $77,533; Brown, Sherwood, NIH, Antidepressant Treatment at Inner-City Asthma Clinic, $408,113; Brown, Sherwood, NIH, Attenuation of Corticosteroid-Induced Hippocampal Changes, $16,218; Brown, Sherwood, NIH, Attenuation of Corticosteroid-Induced Hippocampal Changes - Summer Supplement, $6,156.

Browning, Jeffrey, NIH, Role of Mitochondrial Dysfunction in Non-Alcoholic Fatty Liver Disease, $29,831; Burstein, Ezra, NIH, Control of NF-kB and Inflammation by COMMD Proteins, $22,479; Byerly, Matthew, Columbia Univ./NIH, 2/2: Comparison of Long-Acting Injectable Medication for Schizophrenia (ACLAIMS), $7,710; Casey, Brian, NIH, NICHD Maternal Fetal MED Units Network, $15,348; Castillo, Leticia, NIH, Parenteral Methionine Requirements in Septic Children, $333,722; Chen, Zhijian, NIH, Biochemical Dissection of RIG-I Antiviral Pathway, $15,900; Chuang, David, NIH, Structure and Function of Mitochondrial Protein Kinase, $322,966; Cobb, Melanie, NIH, Insulin-Regulated MAP Kinase Pathways, $479,800; Cobb, Melanie, NIH, MAP Kinase in Islet Function, $23,769; Conrad, Nicholas, NIH, Mechanisms of KSHV Post-Transcriptional Gene Regulation, $295,931; Conrad, Nicholas, NIH, Mechanisms of KSHV Post-Transcriptional Gene Regulation - Diversity Supplement, $58,017; Cullum, Munro, UT Dallas/U.S. Dept. of Defense, Novel Treatment of Emotional Dysfunction in PTSD-Cullum, $129,374.

Deberardinis, Ralph, NIH, Metabolic Regulators of Tumor Cell Growth, $77,533; Dowling, Michael, Univ. of Calif., San Francisco/NIH, Vascular Effects of Infection in Pediatric Stroke: VIPS, $39,564; Eastman, Alexander, Washington Univ. in St. Louis/NIH, Establishing Ethical Framework for Critical-Care Genetics, $81,068; Eisch, Amelia, NIH, Opiates and Adult Neurogenesis, $20,353; Eisch, Amelia, NIH, Opiates and Adult Neurogenesis - Diversity Supplement Rivera, $9,255; Elmquist, Joel, NIH, Leptin Action and Central Melanocortin Systems, $23,049; Falck, Russell, New York Med. Coll./NIH, Hormonal Regulation of Blood Pressure, $127,298; Garcia, Joseph, NIH, Molecular Mechanisms Dictating Sirt1/HIF-2 Signaling During Hypoxia, $323,442; Garrard, William, NIH, Function of Subunits of Eukaryotic Chromosomes, $300,004; Graff, Jonathan, NIH, Hormonal Regulation of Fat Deposition, $473,844; Graff, Jonathan, NIH, Adipocyte Development: Lineage Analysis and Molecular Characterization, $356,376; Greene, Robert, NIH, Glial Control of CNS State-Related Activity, $22,608.

Gupta, Rana, NIH, Defining Adipocyte Progenitors and their Developmental Origins, $79,500; Hedayati, Susan, NIH, Randomized Trial of Sertraline Treatment of Depression in Chronic Kidney Disease, $22,479; Hooper, Lora, NIH, Bacterial Regulation of Intestinal Antimicrobial Defense, $315,194; Huang, Chou-Long, NIH, Regulation of Renal Calcium Transport, $21,230; Huber, Kimberly (N. Tsai, Fellow), NIH, Investigation of Protocadherin-10 in MEF2- and FMRP-Mediated Synapse Elimination, $55,670; Jiang, Qiu-Xing, NIH, Structural Study of a Kv Channel in Different Conformations in Membranes, $288,612; Johnson, Jane, NIH, Regulation and Function of Asc11 in Neural Development, $335,639; Johnson, Jane, NIH, bHLH Transcription Factors in Neural Development, $16,556; Kavalali, Ege, NIH, Role of SNARE Interactions in Central Synapse Function, $373,032; Kliewer, Steven, NIH, Regulation of Metabolism by Hormone FGF15/19, $21,754.

Konopka, Genevieve (D. Araujo, Fellow), Natl. Science Fndtn., Investigating Evolutionary Advantages of Human-Specific Amino Acid Substitutions in Transcription Factor FOXP2, $42,000; Kramer, Helmut, NIH, Genetics of Endocytic Trafficking in Drosophila Eye, $15,900; Kramer, Helmut (L. Tyra, Fellow), Natl. Science Fndtn., Fellowship for Lauren Tyra, $42,000; Kutz, Joe, Nationwide Children’s Hosp./NIH, Virtual Temporal Bone Surgery: Defining and Translating Standardized Metrics to Automated Assessment Tool, $8,500; Le, Lu, U.D. Dept. of Defense, Cell of Origin and Roles of Tumor Microenvironment in Dermal Neurofibroma Development and Therapeutics, $211,999; Lenkinski, Robert, GE Global Research Ctr./NIH, Improving Specificity of Breast MRI through Improved DWI, $176,500; Levine, Beth, NIH, Infectious Diseases Training Program, $128,699; Lin, Rueyling, NIH, Transcriptional Regulation by Wnt Effector POP-1, $15,520.

Lin, Weichun, NIH, Patterning and Formation of Neuromuscular Junction, $22,608; Lu, Qing, NIH, Chromatin Remodeling Control of CNS Myelination and Remyelination, $22,608; Lu, Qing, NIH, Novel Model of Medulloblastoma to Define Cancer Pathways and Molecular Targets, $22,608; Macdonald, Raymond, NIH, Transcriptional Regulators of Exocrine Pancreatic Development, $21,754; Mangelsdorf, David, NIH, Mechanisms of Drug Action and Disposition, $348,750; McKnight, Steven, NIH, Discovery, Characterization, and Preclinical Development of Pro-Neurogenic Drugs, $1,184,388; Meeks, Julian, NIH, Functional Organization of Neural Circuits in Mouse Accessory Olfactory Bulb, $12,426; Mendelson, Carole, NIH, Initiation of Human Labor: Prevention of Prematurity, $61,662; Mendelson, Carole, NIH, Cellular Mechanisms in Induction of Aromatase, $26,071; Miller, David, Gynecologic Oncology Group/NIH, Gynecologic Oncology Group Studies (Per Capita), $43,170.

Mitchell, Mack, Cleveland Clinic/NIH, Novel Therapies in Alcoholic Hepatitis, $352,506; Moe, Orson, NIH, Klotho and FGF23 in Chronic Kidney Disease: Pathogenesis and Potential Therapy, $22,479; Monteggia, Lisa, NIH, Antidepressants and Intracellular Signaling Linked to BDNF, $377,784; Morrison, Sean, NIH, Stem Cells in Peripheral Nervous System Development, $22,155; Mosconi, Matthew, NIH, Motor Control and Cerebellar Maturation in Autism, $157,148; Nedzi, Lucien, American Coll. of Radiology/NIH, Radiation Therapy Oncology Group (RTOG); Agreement No. 5915, $18,100; Nesbitt, Shawna, Minneapolis Med. Research Fndtn. /NIH, ASPirin in Reducing Events in Elderly – Admin. Supplement, $46,452; Nesbitt, Shawna, Minneapolis Med. Research Fndtn./NIH, ASPirin in Reducing Events in Elderly (ASPREE), $4,660; North, Carol, Washington Univ. in St. Louis/NIH, Multidisciplinary Evaluation of Chronic Pelvic Pain Syndrome, $9,535.

Olson, Eric (D. Quiat, Fellow), NIH, Role of miR-210 in Cardiomyocyte Metabolism Following Myocardial Infarction, $11,971; Powell, Craig, NIH, Striatal Synaptic Abnormalities in Models of Autism, $381,600; Pride, Glenn, Med. Univ. of South Carolina/NIH, Stenting vs. Aggressive Medical Management for Preventing Recurrent Events in Intracranial Stenosis (SAMMPRIS), $9,498; Raskin, Philip, NIH, Type 1 Diabetes TrialNet: Clinical Centers (U01), $547,799; Raskin, Philip, Univ. of South Florida/NIH, DPT-1 TrialNet Clinical Centers, $10,526; Rethorst, Chad, NIH, Exercise Intervention to Prevent Interferon-Induced Depression in Hepatitis C Patients, $148,640; Rice, Luke, Natl. Science Fndtn., CAREER: Understanding Microtubule Dynamics Using Biochemically Defined Tubulin Mutants to Integrate Structure, Biochemistry and Kinetics – Admin. Supplement, $4,150; Rizo-Rey, Jose, NIH, Neurotransmitter Release Machinery: Structure and Function, $443,408.

Rizo-Rey, Jose, NIH, Synaptotagmin and C2-Domains: Structure & Function, $26,370; Rodriguez-Baez, Norberto, Johns Hopkins Univ./NIH, Effect of HBV DNA Methylation and Mutant 1762T/1764A on Viral Load and HCC, $231,480; Rodriguez-Baez, Norberto, Univ. of Pittsburgh/NIH, Multicenter Group to Study Acute Liver Failure in Children, $114,485; Roland, Peter, Duke Clinical Research Inst./NIH, CHEER Network: Creating Health Care Excellence through Education and Research, $2,000; Rosen, Michael, NIH, Structural Study of GTPase Regulators and Effectors, $20,751; Rosenfeld, Charles, NIH, Studies of Uteroplacental Circulation, $293,826; Roth, Michael, NIH, Lung Cancer Oncogenotype-Selective Drug Target Discovery (MPI), $526,754; Roth, Michael, NIH, Using Chemical Biology to Interfere with Influenza Virus Life Cycle (MPI), $369,914; Sakhaee, Khashayar, NIH, Pathogenesis of Idiopathic Uric Acid Nephrolithiasis and Renal Lipotoxicity, $322,966.

Sanchez, Pablo, RTI Intl./NIH, NICHD Neonatal Research Network Capitation Funding, $23,933; Schaffer, Joseph, RTI Intl./NIH, NICHD Pelvic Floor Disorders Network - Capitation Funding, $860; Scherer, Philipp, NIH, ACRP, A Protein Secreted From Adipose Tissue, $417,259; Schiller, Joan, Eastern Cooperative Oncology Group/NIH, ECOG Clinical Trials - Federal Payments, $2,350; Schneider, Jay, NIH, Microenvironmental Control of Progenitors in Organ Dysfunction and Repair (MPI), $1,138,045; Seemann, Joachim, NIH, Cell Cycle Regulation of Golgi Membrane Dynamics, $20,670; Self, David, NIH, Role of Endogenous Opiate Systems in Cocaine Relapse After Long-Term Abstinence, $20,560; Shaul, Philip, NIH, Oxysterols, Estrogen Receptor Antagonism and Vascular Disease, $373,458; Sherry, Dean (C. Khemtong, Fellow), U.S. Dept. of Defense, Hyperpolarized 15N Magnetic Resonance Imaging of Tumor Hypoxia in Prostate Cancer, $119,250.

Smith, Dean, NIH, Molecular Basis of Pheromone-Induced Behaviors in Drosophila, $19,875; Sperandio, Vanessa, NIH, Host Pathogen Signaling in Intestine, $185,611; Tambar, Uttam, NIH, Stereoselective Rearrangements for Synthesis of Bioactive Small Molecules, $299,198; Terman, Jonathan, NIH, Molecular Mechanisms of Axon Guidance and Neural Connectivity, $335,729; Terman, Jonathan, NIH, Molecular Mechanisms of Semaphorin/Plexin-Mediated Cytoskeletal Reorganization, $22,608; Timaran, Carlos, Univ. of Medicine and Dentistry of New Jersey/NIH, Carotid Revascularization Endarterectomy vs. Stent Trial (CREST), $4,000; Toto, Robert, Univ. of Utah/NIH, Pulse Wave Velocity and Central Aortic Pressure Outcome in SPRINT, $5,409; Trivedi, Madhukar, NIH, Clinical Trial Network: North Texas Node - Protocol Supplement No. 2, $626,297; Wan, Yihong, NIH, Connection of Mineral and Energy Metabolism by Nuclear Receptor PPAR-Gamma, $338,325.

White, Michael, NIH, Components of RAS-Mediated Growth Control, $76,312; Wright, Tracey, Baylor Med. Ctr./NIH, Systems Biology Approach for Pediatric and Adult Autoimmune Diseases, $34,985; Wright, Woodring, NIH, Manipulating Telomerase Alternative Splicing for Cancer Therapy, $145,167; Yanagisawa, Hiromi, NIH, Protease Regulation and Integrity of Connective Tissues of Pelvic Floor, $300,575; Zhang, Chun-Li, NIH, Transcriptional Control of Adult Neural Stem Cells, $335,639; Zinn, Andrew, NIH, SIM1 Function in Feeding Regulation, $21,754.

Non-Federal Awards

Alto, Neal, Welch Fndtn., Post-Translational Modification of Host Enzymes by Bacterial Effector Proteins, $75,000; Altschuler, Steven, Welch Fndtn., Mechanism and Zonation of Hepatic Crosstalk between Lipogenesis and Canonical Wnt-Signaling, $60,000; Barton, Theresa, Texas Dept. of State Health Services, HIV and STD Program, $200,800; Bezprozvanny, Ilya, Welch Fndtn., Novel Amyloid-Binding Peptoid Ligands as Alzheimer’s Therapeutic, $60,000; Bowers, Daniel, St. Jude Children’s Research Hosp., Risk-Adapted Therapy for Children under 3 Years with Embryonal Brain Tumors, High-Grade Glioma, Choroid Plexus Carcinoma, or Ependymoma, $4,375; Brown, Kathlynn, Welch Fndtn., Design and Synthesis of Tumor-Targeted Drug Delivery Systems for Lung Cancer Therapy, $60,000; D’Orso, Ivan, Welch Fndtn., Cooperative Assembly of HIV Transcription Elongation Complexes, $60,000; Goldsmith, Elizabeth, Welch Fndtn., Docking Interactions Between MAP3Ks, ASK1/TAO2 and B-Raf with their Cognate MAP2Ks MEK6 and MK1, $75,000; Goodman, Joel, Texas Workforce Commission, Summer Merit Program, $60,459; Gumbo, Tawanda, Critical Path Inst./Gates Fndtn., Science-Based Approach to Demonstrate Utility of the Hollow-Fiber Model of Tuberculosis, $30,000; Hooper, Lora, Welch Fndtn., Biochemical and Structural Studies of Novel Retinoid Binding Protein Family, $60,000; Johnson, Jane, Fine Science Tools Inc., Fine Science Tools Travel Award, $1,000; Kim, Taekyung, Welch Fndtn., Biochemical Characterization of Novel Class of Noncoding RNAs, $60,000; Kliewer, Steven, Welch Fndtn., Characterization of Endogenous Ligand for Immunomodulatory Orphan Nuclear Receptor ROR, $100,000; Kurti, Laszlo, Welch Fndtn., Synthesis of Complex Natural Products via Novel C-C Bond-Forming Processes, $60,000; Lee, William (J. Mayberry, Fellow), Amer. Assn. for Study of Liver, 2013 AASLD NP/PA Clinical Hepatology Fellowship Program, $78,000.

Li, Bing, Welch Fndtn., Biochemical and Functional Analysis of Histone Clipping, $60,000; Liou, Jen, Welch Fndtn., Novel Imaging Probes for Investigating ER-Plasma Membrane Junctions, $60,000; Liu, Xin, Welch Fndtn., Structural and Biochemical Studies of Gene Repression by Polycomb Repressive Complex 2: Catalysis and Recruitment, $60,000; Liu, Yi, Welch Fndtn., Biochemical Mechanisms of Small RNA Production Pathways, $100,000; Mangelsdorf, David, Welch Fndtn., Ligand-Binding Properties of Nematode Orphan Nuclear Receptors, $100,000; Nijhawan, Deepak, Damon Runyon Cancer Research Fndtn., Using Chemistry to Identify New Targets in Lung Cancer, $150,000; Orth, Kim, Welch Fndtn., Elucidate Biochemical Mechanism Used by Vibrio VopQ to Induce Autophagy, $100,000; Radhakrishnan, Arun, Welch Fndtn., Fluorescent Sensors for Measuring Cholesterol in Live Cells, $60,000.

Ranganathan, Rama, Welch Fndtn., Structural Principles of Protein Robustness and Evolvability, $100,000; Sanchez, Pablo (J. Cantey, Fellow), Gerber Fndtn., Use and Misuse of Antibiotic Therapy in Neonatal Intensive Care Unit, $12,471; Sun, Xiankai, Juvenile Diabetes Research Fndtn., Imaging Assessment of Pancreatic Beta-Cell Mass and Function, $443,409; Tambar, Uttam, Alfred P. Sloan Fndtn., Alfred P. Sloan Research Fellowship, $25,000; Tu, Benjamin, Welch Fndtn., Selective Regulation of Autophagy by Metabolic State, $60,000; Wu, Lani, Welch Fndtn., On Evolution of Drug-Resistant Lung Cancer Subpopulations, $75,000; Yarovinsky, Felix, Welch Fndtn., Structural Basis of Parasite Recognition by TLR11 and TLR12 Receptors, $60,000; Yu, Gang, Welch Fndtn., Atomic Structure and Mechanism of Gamma-Secretase Complex, $60,000; Yu, Yonghao, Welch Fndtn., Large-Scale Isolation and Identification of Poly-ADP-Ribosylated Proteins, $60,000; Zhang, Chun-Li, Welch Fndtn, Regulation of Orphan Nuclear Receptor TLX by Small Molecules, $60,000.

Industry Sponsored Awards, dollar amounts not available

Anderson, Larry, Phase 3 Study of Pomalidomide, Bortezomib and Low-Dose Dexamethsone vs Bortezomib and Low-Dose Dexamethasone in Subjects with Relapsed or Refractory Multiple Myeloma; Beg, Muhammad, Phase 1/2A Trial of NPC-1C in Adults with Recurrent, Locally Advanced Unresectable or Metastatic Pancreatic and Colorectal Cancer after Standard Therapy; Chin, Kelly, Phase 2 Study of AIR001 in Subjects with WHO Group 1 Pulmonary Arterial Hypertension; Chin, Kelly, Phase 2 Study in Subjects with Pulmonary Arterial Hypertension (PAH, WHO Group 1) and Pulmonary Hypertension Secondary to Idiopathic Pulmonary Fibrosis (PH-IPF WHO Group 3) Using Inhaled NITROSYL; Davis, Kathryn, Activation of Telomeraseby TA-65 in a Porcine Model; Friedman, Deborah, Non-Invasive Neurostimulation of Vagus Nerve with GammaCore® Device for Treatment of Cluster Headache; Greenberg, Benjamin, Study of Tysabri in Early Relapsing-Remitting Multiple Sclerosis in Anti-JCV Antibody Negative Patients.

Journeycake, Janna, Hemophilia Inhibitor PUP Study (HIPS); Lee, William, Phase 3 Study of BI 207127 with Faldaprevir and Ribavirin for Chronic Genotype 1 Hepatitis C Infection in Treatment-Naïve Patients Including those Ineligible for Peginterferon; Lee, William, Efficacy of N-Acetylcysteine (NAC) for Treatment of Acute Liver Failure/Acute Liver Injury; Raskin, Philip, Phase 3 Study of ITCA 650 in Patients with Type 2 Diabetes; Reimold, Andreas, Study of CNTO 136 (Sirukumab), Human Anti-IL-6 Monoclonal Antibody Administered Subcutaneously in Subjects with Active Rheumatoid Arthritis; Saxena, Ramesh, Observational Study of Patients with Atypical Hemolytic-Uremic Syndrome; Saxena, Ramesh, Phase 2 Study of Fresolimumab or Placebo in Patients with Steroid-Resistant Primary Focal Segmental Glomerulosclerosis; Seikaly, Mouin, Study of Sevelamer Carbonate in Hyperphosphatemic Pediatric Patients with Chronic Kidney Disease; Trivedi, Jaya, Study of Mexiletine in Patients with Sporadic Amyotrophic Lateral Sclerosis (SALS).