Awards for June 2013

Federal Awards

Abrams, John, NIH, Genetics Training Program, $178,148; Alto, Neal, NIH, Bacterial Regulation of Eukaryotic Signaling Enzymes: Structure and Function, $19,637; Babb, Tony, NIH, Dyspnea on Exertion in Obesity: Effects of Exercise Training and Weight Loss, $22,339; Beutler, Bruce, NIH, Genetic Analysis of Resistance to Viral Infection, $2,470,019; Bibb, James, NIH, Role of Cdk5 in Stroke, $335,639; Bibb, James, NIH, Novel Signal Transduction Mechanisms in Learning and Memory, $23,611; Boothman, David, NIH, Use of Beta-Lapachone for Lung Cancer Chemotherapy, $335,140; Boothman, David, NIH, Ku70 Binding Protein-5 (KUB5), Novel Factor in Nonhomologous End Joining, $225,619; Bowers, Daniel, St. Jude Children’s Research Hosp./NIH, Childhood Cancer Survivor Study, $4,951; Brekken, Rolf, NIH, Axl as Target for Therapy of Pancreatic Cancer, $51,874; Brown, Kathlynn, NIH, Suite of Tumor-Targeting Peptides for Personalized Therapy of Lung Cancer, $232,597; Brown, Sherwood, NIH, Reversing Corticosteroid-Induced Memory Impairment, $14,166.

Burma, Sandeep, NIH, Molecular Mechanisms of GBM Radioresistance and Strategies for Radiosensitization, $145,167; Burstein, Ezra, NIH, Gastroenterology/Hepatology Research Training Program, $199,024; Butovich, Igor, NIH, Biochemistry and Biophysics of Preocular Tear Film, $15,244; Byerly, Matthew, Columbia Univ./NIH, 2/2: Comparison of Long-Acting Injectable Medication for Schizophrenia (ACLAIMS), $4,490; Cannon, Stephen, NIH, Disease Pathogenesis and Modification for CaV1.1-Associated Hypokalemic Periodic Paralysis, $357,921; Castrillon, Diego, NIH, Mouse Models and Translational Studies of Endometrial Cancer, $156,814; Chen, Benjamin, NIH, DNA-PKcs Phosphorylation on Hematopoietic Stem Cells Genome Maintenance, $161,664; Chen, Chuo, NIH, Identifying Molecular Targets and Biological Signatures of CAM Natural Products, $431,984; Chen, David, NIH, Pathway Choice of DNA Double-Strand Break Repair, $161,664; Chen, David, NIH, Functions of WRN in Response to DNA Double-Strand Breaks, $154,841.

Chen, Zhijian, NIH, Mechanisms of Protein Kinase Activation by Ubiquitin in NF-kB Pathways, $22,220; Chong, Benjamin, NIH, Molecular Markers in Discoid Lupus Erythematous, $123,012; Cowell, Lindsay, NIH, RepServer: Antigen Receptor Repertoire Analysis Pipelines Via the Worldwide Web, $27,132; Crandall, Craig (Z. Schlader, Fellow), NIH, Cognitive Function, Hyperthermia, and Aging, $49,214; Debose-Boyd, Russell, NIH, Dissecting ER-Associated Degradation of Membrane Protein in Drosophila S2 Cells, $296,207; Elmquist, Joel, Massachusetts Gen. Hosp./NIH, Neuroendocrine Response to Gastric Bypass in Nonhuman Primates - ARRA Stimulus RC4, $260,987; Farrar, John, NIH, Type 1 Interferon-Regulated T Helper Development, $14,167; Flores, Glenn, NIH, Randomized Trial of Effects of Parent Mentors on Insuring Minority Children, $522,913; Freeman, Anne, Centers for Disease Control & Prevention, STD/HIV Prevention Training Centers, $243,646; Freeman, Anne, Univ. of California, San Francisco/NIH, Multilevel HIV Prevention Intervention for Young African-American Men, $85,681.

Frohman, Elliot, Southern Methodist Univ./NIH, Dynamic Blood Pressure Control and Orthostatic Tolerance in Individuals with MS at Rest and During Heat Stress, $58,269; Fullinwider, John, Houston Academy of Medicine/NIH, Building Partnerships for Community Health, $14,985; Garcia, Christine, NIH, Pulmonary Fibrosis and Telomerase Dysfunction, $19,863; Garcia, Christine, NIH, Pulmonary Fibrosis and Telomerase Dysfunction-Diversity Supplement, $2,781; Gardner, Kevin, NIH, Molecular Biophysics Predoctoral Training Program, $122,977; Getachew, Yonas, NIH, Drug-Induced Hepatotoxicity During Viral Hepatitis, $142,668; Goldstein, Joseph, NIH, Molecular Basis of Cholesterol Metabolism, $4,077,363; Graff, Jonathan, NIH, Invertebrate Models of Fat Storage, $355,190; Greilich, Philip, New England Research Inst./NIH, Transfusion MED/Hemostasis Clinical Trials Network (TMH), $31,590; Gumbo, Tawanda, Univ. of Pennsylvania/NIH, Immune Activation and Isoniazid Metabolism in HIV/TB, $24,772.

Hall, Christiana, Univ. of Cincinnati/NIH, Ethnic/Racial Variation in Intracerebral Hemorrhage (ERICH), $137,325; Hamra, Kent, NIH, Sperm Stem Cell Libraries for Biological Research (Prev. R24 RR032326), $539,237; Hamra, Kent, NIH, Molecular Mechanisms of Spermatogonial Development, $292,483; Hansen, Eric, NIH, Haemophilus Ducreyi Inhibits Phagocytosis, $15,900; Hansen, Eric, NIH, Surface Proteins of Moraxella Catarrhalis, $13,849; Herz, Joachim, NIH, Metabolism of the VLDL Receptor and ApoE Receptor 2, $20,670; Horton, Jay, Planet Biotechnology Inc. /NIH, Immunoadhesin for Treatment of Hypercholesterolemia (SBIR), $65,001; Hsia, Connie, NIH, Signals for Post-Pneumonectomy Compensatory Lung Growth, $22,147; Hsieh, Jer-Tsong, U.S. Dept. of Defense, Role of MicroRNA in Aggressive Prostate Cancer, $238,500; Husain, Mustafa, NIH, Prolonging Remission in Depressed Elderly (PRIDE), $13,861.

Idris, Ahamed, NIH, Resuscitation Outcomes Consortium Regional Clinical Center - DFWCRR, $8,268; Janowski, Bethany, NIH, Molecular Switches: Regulatory RNAs Targeting Nuclear Hormone Receptor Promoters, $237,584; Jarrett, Robin, NIH, 1/2 Preventing Perinatal Depression (PRE-D): Developing Tools and Interventions (MPI), $228,960; Jiang, Jin, NIH, Mechanism of Hedgehog Signal Transduction Across Plasma Membrane, $311,397; Jiang, Youxing, NIH, Molecular Mechanisms of Cation Channel Selectivity, $18,810; Johnson, Mark, Yale Univ./NIH, Insulin Resistance Intervention after Stroke (IRIS) Trial, $1,830; Kavalali, Ege, NIH, Cellular Biophysics of Neuron Training Program, $127,050; Khera, Amit, Yale Univ./NIH, Young Women with Acute Myocardial Infarction (VIRGO), $700; Konopka, Genevieve, NIH, FOXP2-Regulated Signaling Pathways Critical for Higher Cognitive Functions, $18,239; Lee, Simon, NIH, Interpersonal Framework for Lung Cancer Decision-Making in African-Americans, $38,955.

Levine, Benjamin, NIH, Aging, Fitness, & Failure: Mechanisms of Diastolic Dysfunction, $526,147; Levine, Benjamin, NIH, Aging, Fitness, & Failure: Mechanisms of Diastolic Dysfunction - Diversity Supplement, $83,457; Levine, Benjamin, Natl. Space Biomedical Research Inst., Team Leader for Cardiovascular Alterations Team, $60,000; Li, Wen-Hong, NIH, Photonic Probe and Techniques for Biological Imaging Applications, $322,214; Liu, Yi, NIH, Molecular Mechanisms of Neurospora Circadian Clock, $311,397; Liu, Zhi-Ping, NIH, Epigenetic Regulation of Cardiac Hypertrophy and Heart Failure, $20,670; Lum, Lawrence, NIH, Chemical Disruption of Wnt-Mediated Signal Transduction, $116,002; Macmillan, John, NIH, Marine Actinomycetes as Resource for Anticancer Natural Products, $300,825; Maher, Elizabeth, NIH, Defining Metabolic Phenotype of Low-Grade Gliomas in Vivo, $161,664; Martinez, Elisabeth, NIH, Characterization of Biological Activities of Novel Epigenetic Modulators, $156,814; Mason, Ralph, NIH, Hypoxia and Radiotherapy: Evaluation and Mitigation in Tumors, $140,812.

Michaely, Peter, NIH, Characterization of Role of ARH on LDLR Function, $12,402; Mootha, Venkateswara, NIH, Genetics and Genomics of Fuchs Endothelial Corneal Dystrophy, $15,900; Nesbitt, Shawna, Minneapolis Med. Research Fndtn./NIH, ASPirin in Reducing Events in Elderly (ASPREE), $11,980; Nesbitt, Shawna, UT HSC at Houston/NIH, Randomized Recruitment Intervention (RECRUIT), $3,000; Niederkorn, Jerry, NIH, Immunological Modulation of Ocular Tumor Metastases, $141,086; Niederkorn, Jerry, NIH, Transplant and Tumor Rejection Processes Within the Eye - Diversity Supplement, $92,821; Norgard, Michael, UT Med. Branch/NIH, Outer Membrane Proteins of Francisella Tularensis as Acellular Vaccines, $357,610; Norgard, Michael, NIH, Molecular Microbiology Training Grant, $268,180; Norgard, Michael, NIH, RpoN-RpoS Regulatory Pathway in Borrellia Burgdorferi, $15,741; Norgard, Michael, NIH, Structure and Function of Treponema Pallidum Lipoproteins, $15,388.

Nwariaku, Ohwofiemu, NIH, Training in Trauma, Inflammation, Sepsis, and Critical Care, $119,461; Olson, Eric, NIH, Heart Repair Through Reprogramming of Cardiac Cell Fate, $505,777; Olson, Eric, NIH, MicroRNA Control of Cardiac Gene Expression, Function, and Disease, $503,133; Olson, Eric, NIH, MicroRNA Control of Cardiac Gene Expression, Function, and Disease - Diversity Supplement, $53,184; Orth, Kim, NIH, Analysis of Orchestrated Cell Death Mediated by Vibrio Parahaemolytics T3SS1, $15,741; Otwinowski, Zbyszek, NIH, Crystallography of Macromolecules, $20,824; Parada, Luis, NIH, Genetic Mouse Models of Glioma, $190,382; Pearson, Gray, NIH, Investigating Breast Cancer Collective Invasion, $161,664; Powell, Craig, NIH, Neuroligin Function in Vivo: Implications for Autism and Mental Retardation, $23,314; Raskin, Philip, Case Western Reserve Univ./NIH, Epidemiology of Diabetes Interventions and Complications (EDIC), $251,171; Raskin, Philip, Univ. of South Florida/NIH, DPT-1 TrialNet Clinical Centers, $8,474.

Ready, Joseph, NIH, Synthesis and Evaluation of Biologically Active Natural Products, $294,701; Rice, Luke, NIH, Conformation and Recognition in Microtubule Dynamics, $291,527; Rosenberg, Roger, NIH, Neurobiology of Alzheimer’s Disease and Aging, $1,610,444; Ross, Elliott, NIH, G Protein-Coupled Receptors - Structure and Regulation, $25,838; Roth, Michael, NIH, Novel Inhibitors of Viral Replication (MPI), $377,242; Rothenfluh, Adrian, NIH, Control of Alcohol Responses by Actin-Regulating Genes, $10,888; Sanchez, Pablo, NIH, NICHD Cooperative Multicenter Neonatal Research Network, $15,346; Sanchez, Pablo, RTI Intl./NIH, NICHD Neonatal Research Network Capitation Funding, $13,227; Scaglioni, Pier, NIH, Characterization and Drug Targeting of PML Tumor Suppressor in Lung Cancer, $297,042; Schaffer, Joseph, RTI Intl./NIH, NICHD Pelvic Floor Disorders Network - Capitation Funding, $1,560.

Schmid, Sandra, NIH, Mechanisms Regulating Clathrin-Mediated Endocytosis, $27,249; Schmid, Sandra, NIH, Clathrin-Coated Vesicle Cycle, $27,215; Schmid, Sandra, NIH, Defining the Role of Dynamin in Endocytosis, $24,847; Schwarz, Margaret, NIH, EMAP II: Pulmonary Vascular Mediator, $423,493; Sherry, Dean, NIH, PARACEST Agents for Molecular Imaging of Cancer by MRI, $131,309; Slone, Tamra, Children’s Hosp. and Health System/NIH, COG CHOP Cancer Control Grant, $7,433; Souza, Rhonda, NIH, Basic and Clinical Studies on Role of Bile Acids in Barrett’s Esophagus (MPI), $124,268; Sperandio, Vanessa, NIH, Quorum Sensing Regulation of EHEC Virulence Genes, $19,078; Sperandio, Vanessa, NIH, SdiA Regulation of EHEC Virulence, $15,121; Thankavel, Poonam, New England Research Inst./NIH, Pediatric Echocardiography Z-Score and Electrocardiogram, $1,612; Tiro, Jasmin, NIH, Developing a Self-Persuasion Intervention Promoting Adolescent HPV Vaccination, $447,634.

Trivedi, Madhukar, Massachusetts Gen. Hosp./NIH, Rapidly Acting Treatments for Treatment-Resistant Depression (RAPID), $194,644; Trivedi, Madhukar, Massachusetts Gen. Hosp./NIH, Rapidly Acting Treatments for Treatment-Resistant Depression (RAPID), $32,434; Turley, Stephen, NIH, Disordered Cellular Cholesterol Movement, Cell Death, and Multisystem Disease, $827,892; Udugamasooriya, Damith, NIH, Phosphatidylserine-Targeted Tumor Cell Lytic Peptoids, $98,217; Wang, David, NIH, Hedgehog Signaling in the Development of Barrett’s Esophagus, $287,096; Wolf, Matthias, NIH, Role of Uromodulin in Regulation of Renal Calcium Channel TRPV5, $145,331; Xie, Yang, NIH, Predicting Adjuvant Chemotherapy Response in Lung Cancer, $164,662; Yan, Nan, NIH, HIV Subversion of Innate Immunity, $15,900; Yanagisawa, Hiromi, NIH, Loss of Matrix Regulation and Aortic Aneurysm Development in Vivo, $20,699.

Yarovinsky, Felix, NIH, Cellular and Molecular Mechanisms of Host Resistance to Toxoplasma Gondii, $15,741; Ye, Jin, NIH, Regulated Intramembrane Proteolysis of CREB3L1 in Innate Antiviral Response, $369,914; Zhu, Hao, NIH, Metabolic Roles for Lin28-let-7 MicroRNA Pathway in Sarcoma Tumorigenesis, $161,460; Zigman, Jeffrey, NIH, Ghrelin’s Role in Mood, $23,611.

Non-Federal Awards

Bradley-Guidry, Carolyn, Susan G. Komen for the Cure, Screening Our Sisters, $14,514; Carroll, Thomas, March of Dimes Fndtn., Delineating Role for Non-Canonical WNT Signaling in Kidney Morphogenesis, $111,575; Cobb, Melanie, CPRIT, Coordination of Inputs from Taste Receptors and Ras/ERK1/2 Axis to mTORC1: Mechanisms and Pathway Interactions in Cancer, $405,000; Fu, Qi, American Heart Assn. Southwest Affiliate, Neural Mechanisms in Gestational Hypertension and Preeclampsia, $70,000; Gao, Jinming, CPRIT, Beta-Lapachone Nanotherapeutics for NQO1-Targeted Therapy of Cancer, $333,127; Herz, Joachim, Univ. of California, San Francisco, Consortium for Frontotemporal Dementia Research, $264,000; Huber, Kimberly (W. Guo, Fellow), Fraxa Research Fndtn., Evaluation of CamKll Dependent Regulation of mGluR5-Homer Scaffolds as Potential Therapeutic for Fragile X Syndrome, $45,000; Liu, Qinghua, American Heart Assn. Southwest Affiliate, Novel Regulators of Human RNAi and MicroRNA Pathways, $70,000.

Olson, Daiwai, UT System, Quality Care Improvement with Nursing-Driven Acute Stroke Care, $29,949; Parada, Luis, Johns Hopkins Univ., Primary Plexiform Neurofibroma Cell Culture Model for Use in Cell-Based High-Throughput Screens, $165,000; Parada, Luis (W. Mo, Fellow), Children’s Tumor Fndtn., Identify the Cancer Stem Cells in MPNSTs, $52,750; Parada, Luis (X. Xie, Fellow), American Brain Tumor Assn., Investigating the Role of Cancer Stem Cells in a Mouse Model of Glioblastoma, $50,000; Skapek, Stephen, Seattle Children’s Research Inst./St. Baldrick’s Fndtn., Prognostic Significance of Fusion Status in Low- and High-Risk Rhabdomyosarcoma, $3,477; Story, Michael, CPRIT, P1: Enhancing Identification of Markers and Potential Therapeutic Targets for Improving Tumor Response via MIRNA and DNA Methylation Analysis, $283,755.

Wu, Jiang, American Cancer Society, Epigenetic Regulation of Mammalian Sonic Hedgehog Signaling Pathway, $180,000; Wu, Jiang, March of Dimes Birth Defects Fndtn., Decoding Chromatin Regulation of Sonic Hedgehog Signaling with Proteomic Approaches, $110,167; Yarovinsky, Felix, Burroughs Wellcome Fund, New Arm of Innate Immunity: TLR-Independent Neutrophil-IFN-Gamma in Host Protection Against Microbial Infection, $100,000.

Industry Sponsored Awards, dollar amounts not available

Anderson, Larry, Prospective Research Assessment in Multiple Myeloma: Observational Evaluation (PREAMBLE); Banerjee, Subhash, XLPAD Study; Carr, Bruce, Extension Study of Elagolix in Subjects with Moderate to Severe Endometriosis-Associated Pain; Choe, Kevin, Trial of NovoTTF-100A Together with Temozolomide Compared to Temozolomide Alone in Patients with Newly Diagnosed GBM; Collins, Robert, Phase 3 Study of Inotuzumab Ozogamicin Compared to Defined Investigator’s Choice in Adult Patients with Relapsed or Refractory CD22-Positive Acute Lymphoblastic Leukemia(ALL); Courtney, Kevin, Phase 2 Study of PSMA ADC in Subjects with Castration-Resistant Metastatic Prostate Cancer (CRMPC); Frohman, Elliot, Phase 4 Trial of Neuroprotection with ACTH in Acute Optic Neuritis; Haley, Barbara, Phase 2 Study of BKM120 Plus Paclitaxel in Patients with HER2-Negative Inoperable Locally Advanced Metastatic Breast Cancer; Haley, Barbara, Phase 2 Study of BKM120 with Fulvestrant in Postmenopausal Women with Hormone Receptor-Positive HER2-Negative AI Treated, Locally Advanced, or Metastatic Breast Cancer Who Progressed on or after mTOR Inhibitor-Based Treatment.

Jain, Mamta, EGRIFTA Diabetic Retinopathy Study; Joglar, Jose, Quadripolar Pacing Post-Approval Study (QUAD PAS); Lavery, Lawrence, Effects of Topical Application of GSK1278863 in Healthy Volunteers and in Diabetic Patients for Treatment of Diabetic Foot Ulcers; Lee, William, SQUELCH-C: Study of Quadruple Therapy with Eltrombopag for Chronic Hepatitis C; Mitchell, Ron, Trial of Ciprofloxacin .3% plus Fluocinolone Acetonide .025% Otic Solution Compared to Ciprofloxacin .3% Otic Solution and to Fluocinolone Acetonide .025% Otic Solution in Treatment of AOMT in Pediatric Patients; Naina, Harris, Phase 3 Study of Dinaciclib or Ofatumab in Subjects with Refractory Chronic Lynphocytic Leukemia; O'Suilleabhain, Padraig, Study of 18F-AV-133 PET Imaging to Identify Subjects with Dopaminergic Degeneration Among Subjects Presenting to Movement Disorders Specialty Clinic with Uncertain Diagnosis; Raj, Ganesh, Targeted Disruption of Androgen Receptor and Cofactors; Reimold, Andreas, Phase 3b Study of Subcutaneous LY2127399 in Patients with Systemic Lupus Erythematosus (SLE) (ILLUMINATE-X).

Rodriguez-Baez, Norberto, Phase 1/2 Study of Telaprevir in Combination with Peginterferon alfa-2b and Ribavirin in Pediatric Subjects Aged 3-17 Infected with Genotype 1 Hepatitis C Virus; Roland, Peter, Electrode Insertion Temporal Bone Study; Saxena, Ramesh, Phase 3 Study of Belimumab vs. Placebo for Standard Care of Adult Subjects with Active Lupus Nephritis; Story, Michael, Novocure TTF and TTF plus Radiation; Phase 1 in Vitro Studies; Teotia, Sumeet, Trial Using Dissolved Oxygen Enriched Dressing in Nipple-Sparing Mastectomies; Timaran, Carlos, Carotid Artery Stenting Outcomes in Standard Risk Population for Carotid Endarterectomy-(CANOPY).