February 2009 Grants

Adinoff, B., NIH, Stress, HPA Axis Dysfunction, and Relapse in Alcoholism, $207,386; Anderson, R., NIH, Caveolae Structure and Function, $278,135;  Brown, E. S., NIH, Development of a Model to Examine Corticosteroid Effects on the Hippocampus, $121,500;  Brown, E. S., NIH, Citicoline for Bipolar Disorder and Cocaine Dependence, $205,176;  Buchanan, G., NIH/UT Health Science Center at Houston, Region IV Comprehensive Hemophilia Program, $31,160.

Buchanan, G., NIH/UT Health Science Center at Houston, Prevention of the Complications of Bleeding Disorders through Hemophilia Treatment, $54,542; Burstein, E., NIH, Control of NF-KB and Inflammation by COMMD Proteins, $126,567;  Cadeddu, J., ETF/UTD, Future Semiconductor Commercialization (FUSION), $400,000; Chan, R., NIH/McGill University, Design, Construction and Evaluation of Implants for Vocal Fold Alternation and Reconstruction, $58,899; Chen, P., NIH, Epigenetic Gene Regulation by the Ocular Environment, $180,000. 

Cobb, M., NIH, Regulation and Function of ste20-Related Protein Kinases, $290,001; Diaz-Arrastia, R., NIH/University of California, San Diego, Immunoglobulin Intravenous (IgIV) for Treatment of Alzheimer’s Disease, $3,000; Dowling, M., NIH/The Children’s Hospital of Philadelphia, Validation of NIH Stroke Scale in Children, $15,984;  Freeman, A., NIH/University of California, San Francisco, A Community-Level HIV Prevention Intervention for Young Black Men, $74,726;  Garner, H., DOD/Lynntech, Inc. Expedited High-Affinity Ligand Generation from Biomarker Sequence by Integration of Data Mining with High-Throughput Screening, $2,500.

Garner, H., Texas AgriLife Research/Texas A & M University, The National Cener for Foreign Animal and Zoonotic Disease Defense, $58,800;  Gazdar, A., NIH/University of Cincinnati, Genetic Epidemiology in Lung Cancer, $38,776; Halm, E., NIH/The University of New Jersey, Self-Regulation and Self-Management in Older Asthmatics, $105,632; Hendrixson, D., NIH, Campylobacter Jejuni  Flagellar Regulation and Synthesis, $192,892; Hendrixson, D., USDA, Regulation of Capsular Polysaccharide Production in Campylobacter Jejuni and its Role in Host Interactions, $110,000. 

Hill, J., NIH, Calcineurin-Mediated Regulation of Cardiac Ca2 Channel, $213,341; Hill, J., NIH, HDAC Inhibition in Cardiac Hypertrophy and Failure, $250,000;  Huang, C.L., Nih, Membrane Trafficking of Renal Potassium Channel, $208,250; Huang, H., NIH/UT-Austin, Cerebellar Anatomic and Functional Connectivity in Autism Spectrum Disorders, $10,062; Jarrett, R., NIH, Cognitive Therapy for High Risk & Refractory Depression, $121,578.  

Jarrett, R., NIH, Are Cognitive Therapy’s AntidepressantEffects Durable? $197,742; Jin, E., NIH, Role of Excess Glycogenolysis in Fasting Hyperglycemia in Obesity-Associated T2DM, $80,112; Johnson, M., NIH/Yale University School of Medicine, Insulin Resistance Intervention after Stroke Trial (IRIS Study), $3,227.58; Karandikar, N., NIH, Dissecting the Immune Basis of Disease and Therapy, $169,004; Kernie, S., NIH, The Role of Neural Stem Cells in Traumatic Brain Injury, $196,628.

Liu, Y., NIH, Double-Stranded RNA-Mediated Signaling Pathway and Gene Silencing, $180,000; Liu, Y., NIH, Molecular Mechanisms of the Neurospora Circadian Clock, $174,780; MacDonald, R., NIH, Determining the Developmental Progression of PTF1 Targets by ChIP-Seq, $150,000;  McPhaul, M., R. L. Kirschstein T-35 to Support NHLBI-Focused Short-Term Predoctoral Training, $39,918;  Medin, P., NIH, Spinal Cord Tolerance to Radiosurgical Dose Delivery, $202,090; Mohan, C., NIH, NIAMS: CORT – Genetic Dissection of SLE – From Mouse to Man, $212,102;  Muallem, S., NIH, Signaling Mechanisms in Salivary Gland Cells, $215,850;  Nwariaku, F., NIH, Pathophysiological Biochemical Changes of Thermal Injury, $846,031.

Peng F., NIH, Human Copper Transporter 1 as Reporter Gene for Imaging, $93,587;  Porteus, M., NIH, Using Zinc Finger Nucleases to Stimulate Gene Targeting in HSC, $218,475; Porteus, M., NIH/Georgia Institute of Technology, Nanomedicine Center for Nucleoprotein Machines, $114,650;  Ready, J., NSF, CAREER:  Selective Functionalization of Alkynes, $85,987; Rodriquez-Baez, N., NIH/Children’s Hospital of Pittsburgh of UPMC, A Multi-Center Group to Study Acute Liver Failure in Children, $20,342. 

Ross, E., NIH, G Protein-Coupled Receptors – Structure and Regulation, $220,500;  Scheuermann, R.,   NIH/Northrop Grumman Information Systems, Bioinformatics Resource Centers for Biodefense and Emerging/Re-Emerging Infectious Diseases, $146,355;

Self, D., NIH, VTA Ionotropic Glutamate Receptors in Cocaine Addiction, $208,659;  Stull, J., NIH, Roles of Myosin Light Chain Kinases in the Heart, $242,750;  Stull, J., NIH, Myosin Light Chain Kinase Function in Smooth Muscle, $237,045.

Velez, N., Targeting Trypanosoma Brucei S-adenosylmethionine Decarboxylase in Drug Discovery, $28,332;  Wakeland, E., NIH, Genetic Pathways Contributing to SLE Pathogenesis, $263,688;  Wetherington, C., NIH/Cincinnati Childrens’s Hospital Medical Center, Promoting Treatment Adherence in Adolescent Leukemia, $70,110;  Winkler, W., NIH/UT Health Science Center at Houston, Regulation of Ethanolamine Utilization in E.faecalis and Atypical Riboswitch, $15,802;  Wright, W., NIH/Boston Biomedical Research Institute,  Biomarkers for Therapy of FSHD, $95,000. 

Yin, Y., DOD, Androgen Deprivation Therapy Induces a Marker for Immunotherapy of Prostate Cancer, $56,392; Zhang, H., NIH/Burnham Institute for Medical Research, Targeting Cofactor Biosynthesis in Biodefense Pathogens, $41,591.

Nonfederal Grants 

Buszczak, M., March of Dimes Birth Defects Foundation, Systematic Characterization of Histone Demethylases in Drosophila Stem Cells, $68,181; Feranchak, A., Cystic Fibrosis Foundation, Regulation of Biliary Secretion by Mechanosensitive Pathways, $90,000; Garg, V., The Children’s Heart Foundation, Genetics of Hypoplastic Left Heart Syndrome, $70,000; Li, W. H., Juvenile Diabetes Research Foundation, Measuring Beta Cell Function in Human Islets by MRI, $218,284; Mohan. C., Alliance for Lupus Research Kallikreins in Lupus Nephritis, $219,902.

Rahn, D., The American Urogynecologic Society, Effect of Preoperative Estrogen Treatment on Connective Tissues of the Pelvic Floor, $15,000; Starr, A., Orthopaedic Trauma Association, Early Psychiatric Intervention after Orthopaedic Trauma:  A Prospective Randomized Double-Blinded Placebo Controlled Trial, $49,602;  Wyckoff, M., American Academy of Pediatrics, Effectiveness of Plastic Lined Hats for Prevention of Hypothermia in Premature Newborns in the Delivery Room,  $7,500, (Fellow – L. St. John);  Zhang, C., March of Dimes Birth Defects Foundation, Study of Hematopoietic Stem Cells and Their Intrinsic Control, $68,182. 
 

Pharmaceutical studies,  dollar amounts not available

Byerly, M., A Randomized, Double-Blind, Parallel-Group, Flexible-Dose Study Exploring the Neurocognitive Effect of Sertindole versus Quetiapine in Patients with Schizophrenia Using the MATRICS Consensus Cognitive Battery (MCCB^™);  Huo, M., A Phase 4, Multicenter, Open-Label, Observational Study Assessing the Impact of Exposure to Study Drug on Coagulation Parameters;  Journeycake, J., An Open-Label Study to Evaluate Prophylaxis Treatment, and to Characterize the Efficacy, Safety, and Pharmacokinetics of study drug in Children with Hemophilia A.

Raskin, P., A Randomized, Blinded, Placebo Controlled, Safety and Pharmacodynamic Study of Study Drug with Open Label Cross-Over in Subjects with Type I Diabetes Mellitus; Torres, F., A Single-Dose, Dose-Escalating Study Exploring the Safety, Pharmacokinetics, and Inhalation Device in Patients with Pulmonary Hypertension Associated with Idiopathic Pulmonary Fibrosis.