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2024 Article Archive

Lung cancer treatment shows promise in tumor models

 

A molecule has demonstrated its ability to kill tumor cells and incite an immune response in preclinical models of small cell lung cancer (SCLC), according to UT Southwestern Medical Center researchers.

Simmons Cancer Center awarded nearly $19 million in CPRIT funding

 

Nine scientists and physicians in the Harold C. Simmons Comprehensive Cancer Center at UT Southwestern Medical Center have been awarded nearly $13 million in grants from the Cancer Prevention and Research Institute of Texas (CPRIT) to support research and prevention efforts on a wide range of cancer issues.

UTSW team’s new AI method may lead to ‘automated scientists’

 

UT Southwestern Medical Center researchers have developed an artificial intelligence (AI) method that writes its own algorithms and may one day operate as an “automated scientist” to extract the meaning behind complex datasets.

How an experimental drug reverses fatty liver disease

 

A drug in clinical trials as a treatment for metabolic dysfunction-associated steatotic liver disease (MASLD) works with a one-two punch that shuts down triglyceride production and fatty acid synthesis in liver cells, UT Southwestern Medical Center researchers show in a new study.

How gut bacteria become ‘persisters’ to avoid antibiotics

 

A subpopulation of gut bacteria given a commonly used antibiotic became “persisters” that were able to survive without developing true resistance, UT Southwestern Medical Center scientists discovered.

UT Southwestern finds genetic clues to complex infections

 

Treating complex bacterial infections with customized therapies tailored to the infection and the patient is closer to reality, thanks to researchers at UT Southwestern Medical Center.

UT Southwestern study shows glucagon is key for kidney health

 

Glucagon, a hormone best known for promoting blood sugar production in the liver, also appears to play a key role in maintaining kidney health.

Age, sex, race among top risk factors for revision knee surgery

 

Patients who are younger than about 40, male, or Black are among those most at risk for revision surgery after having had a total knee replacement, according to researchers at UT Southwestern Medical Center.

Experimental compound kills cancer, spares immune cells

 

UT Southwestern Medical Center researchers have identified a compound that selectively eliminates cancer cells while sparing immune cells in a form of cell death known as ferroptosis.

In Memoriam: Jonathan W. Uhr, M.D., renowned immunologist and longtime Chair of Microbiology

 

In Memoriam: Jonathan W. Uhr, M.D., renowned immunologist and longtime Chair of Microbiology